Estrogen Receptor α(ER) Monoclonal Antibody

Name: Estrogen Receptor α(ER) Monoclonal Antibody
Brand: Elabscience
SKU: PA6541
Price: 315 USD
Availability: InStock

Catalog number:PA6541

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Price: $315

Reactivity: Human

Applications: IHC-P

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Size	3mL/6mL(Ready-to-Use) 100μL/200μL(Concentrated)
Source	Mouse
Clone No.	YN00806m
Reactivity	Human
Application	IHC-P
Background	Estrogen receptor (ER) is a steroid receptor of nuclear receptor superfamily, which consists of 553 aa. ER have three domains: the central domain of DNA binding, the hormone binding domain of C-terminal and the transcriptional activation domain of N-terminal. ER is involved in the regulation of female sex hormones, mainly mediating the growth, differentiation and other functions of 17 (E2) on several target tissues . ER α is expressed in the nucleus of epithelial cells of normal breast and endometrium, and also in breast cancer. Immunohistochemistry analysis showed that the overall survival rate of steroid positive prediction is good. RE α can also be used as a tumor marker combined with anti-progesterone receptor antibody.

Immunohistochemistry of paraffinembedded Human breast cancer tissue with Estrogen Receptor α(ER) Monoclonal Antibody(Antigen repaired by EDTA).

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Cat. No	PA6541
Application