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MutS Protein Homolog 6(MSH6) Monoclonal Antibody

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      Catalog number:PA6196

      Size:
      • 3mL
      • 6mL
      • 100μL
      • 200μL
      Qty:
      - +
      Price: $200

      Reactivity: Human

      Applications: IHC-P

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      Overview

      Size 3mL/6mL(Ready-to-Use)     100μL/200μL(Concentrated)
      Source Mouse
      Clone No. YN01136m
      Reactivity Human
      Application IHC-P
      Background MSH6, known as MutS homolog 6 (E.coli), is a mismatch repair gene. DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite's reproducibility is caused by the slippage of the hinge misalignment during DNA replication, which is also called microsatellite instability. Mutant mismatch repair proteins are often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal cancer (HNPCC), and sporadic (MSI-H) colorectal cancer. MLH1, MSH2, MSH6 antibodies can be used to screen the disease in patients and their families.

      Images

      Immunohistochemistry of paraffinembedded Human colon cancer tissue with MutS Protein Homolog 6(MSH6) Monoclonal Antibody(Antigen repaired by EDTA).

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      MSDS for ELISA ISO 9001

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