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QuicKey Human VEGF-A(Vascular Endothelial Growth Factor A) ELISA Kit

  • Cat.No.:E-TSEL-H0026

  • Reactivity: Human

To Purchase E-TSEL-H0026

Size:
  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $390
Qty:

Product Details

QuicKey Series

Get more sensitive and precise results with saving at least 1h comparing to traditional ELISA Kits. The new developed technology in house will help to accelerate your science research in a more efficient way.

Properties

Assay type Sandwich-ELISA
Format 96T/48T
Assay time 2.5h
Detection range 0.04-10 ng/mL
Sensitivity 0.03 ng/mL
Sample type &Sample volume serum and plasma; 50μL
Specificity This kit recognizes Human VEGF-A in samples. No significant or interference between Human VEGF-A and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of Human VEGF-A concentrations in serum and plasma.Please consult technical support for the applicability if other biological fluids need to be tested.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human VEGF-A. Samples (or Standards) and biotinylated detection antibody specific for Human VEGF-A are added to the micro ELISA plate wells. Human VEGF-A would combine with the specific antibody. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human VEGF-A, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 ± 2 nm. The OD value is proportional to the concentration of Human VEGF-A. You can calculate the concentration of Human VEGF-A in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for six months. After test, the unused wells and reagents should be stored according to the table below.
ItemSpecificationsStorage conditions after test
Micro ELISA Plate (Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips
2-8℃, 1 month
Reference Standard 96T: 2 vials
48T: 1 vial
Discard unused reconstituted standard and dilutions
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8℃
Biotinylated Detection Ab Working Solution 1 vial, 6 mL
HRP Conjugate Diluent 1 vial, 14 mL
Concentrated Wash Buffer (25×) 1 vial, 30 mL
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
2-8℃ (Protect from light)
Substrate Reagent 1 vial, 10 mL
Stop Solution 1 vial, 10 mL 2-8℃
Plate Sealer 5 pieces
Product Description 1 copy
Certificate of Analysis 1 copy

Technical Data

Sample Values

sandwich-Ab-ELISA-Elabscience

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human VEGF-A were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human VEGF-A were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (ng/mL) 0.48 1.13 4.28 0.42 1.19 4.51
Standard deviation 0.03 0.05 0.21 0.02 0.06 0.22
CV (%) 6.25 4.42 4.91 4.76 5.04 4.88

Recovery

The recovery of Human VEGF-A spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 86-97 91
EDTA plasma(n=8) 82-96 90

Linearity

Samples were spiked with high concentrations of Human VEGF-A and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

sandwich-Ab-ELISA-Elabscience

Target Information

Background

Vascular endothelial growth factor A(VEGF-A) is a multifunctional cytokine that exerts in vivo a key role in physiological and pathological neoangiogenesis by stimulating endothelial cell proliferation and vessel hyperpermeability.[1] It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. In human, VEGF-A is produced by a group of isoforms as a result of alternative splicing and VEGF189, VEGF165, VEGF121 are widely expressed. Elevated levels of this protein is linked to POEMS syndrome, mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy.[2] VEGF-A also has a major role in the pathogenesis of many other diseases including hypervascularized tumors, rheumatoid arthritis, cutaneous diseases. [3]
1. Murphy J F , Fitzgerald D J . Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor[J]. The FASEB Journal, 2001, 15(9):1667-1669.
2. Watanabe D, Suzuma K, Suzuma I, et al. Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy[J]. American journal of ophthalmology, 2005, 139(3): 476-481.
Database LinksSwissProt: P15692
Entrez Gene: 7422
SynonymsVEGF-A, VEGFA, MVCD1, VPF
Research AreaCancer, Cardiovascular, Metabolism, Developmental biology, Signal transduction

Assay Procedures

step01

1. Add 50μL standard or sample to the wells, immediately add 50μL Biotinylated Detection Ab working solution to each well. Incubate for 90 min at 37°C

step02

2. Aspirate and wash the plate for 3 times

step03

3. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times

step04

4. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C

step05

5. Add 50μL Stop Solution

step06

6. Read the plate at 450nm immediately. Calculation of the results

Citations

  1. BIOMATERIALS (2022) IF: 15.304
    Sequential oxygen supply system promotes peripheral nerve regeneration by enhancing Schwann cells survival and angiogenesis

    DOI: 10.1016/j.biomaterials.2022.121755

    PMID: 36049427

    Sample: HUVEC
  2. CHEMICAL ENGINEERING JOURNAL (2022) IF: 13.273
    Regulation of macrophage subtype via injectable micro/nano-structured porous microsphere for reprogramming osteoimmune microenvironment

    DOI: 10.1016/j.cej.2022.135692

    Sample: HUVECs
  3. JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
    Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke

    DOI: 10.1186/s12951-022-01461-2

    PMID: 35642036

    Sample: PLGA-FE
  4. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
    HIF1α lactylation enhances KIAA1199 transcription to promote angiogenesis and vasculogenic mimicry in prostate cancer

    DOI: 10.1016/j.ijbiomac.2022.10.014

    PMID: 36209908

    Sample: PC-3 cells,DU145 cells
  5. Cell Death & Disease (2022) IF: 8.4689
    A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer

    DOI: 10.1038/s41419-022-04734-8

    PMID: 35365616

    Sample: HCT-116 cell,HT-29 cell
  6. CELL PROLIFERATION (2022) IF: 8.7550
    Tetrahedral framework nucleic acids promote diabetic wound healing via the Wnt signalling pathway

    DOI: 10.1111/cpr.13316

    PMID: 35869570

    Sample: HDFs
  7. CLINICAL CANCER RESEARCH (2019) IF: 8.911
    Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine–Paracrine Loop

    DOI: 10.1158/1078-0432.CCR-18-2544

    Sample: tumor-infiltrating neutrophils (TINs),neutrophils
  8. CANCER LETTERS (2020) IF: 7.36
    Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner

    DOI: 10.1016/j.canlet.2020.08.030

    PMID: 32860852

    Sample: Cell culture supernatant
  9. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    Early Osteogenic Marker Expression in hMSCs Cultured onto Acid Etching-Derived Micro- and Nanotopography 3D-Printed Titanium Surfaces

    DOI: 10.3390/ijms23137070

    PMID: 35806083

    Sample: hBM-MSCs
  10. Frontiers in Oncology (2021) IF: 6.244
    Single-Cell Transcriptomics Reveals the Complexity of the Tumor Microenvironment of Treatment-Naive Osteosarcoma

    DOI: 10.3389/fonc.2021.709210

    PMID: 34367994

    Sample: MG63 cells,U-2 OS cells,Saos-2 cells, 143B cells,K
  11. Frontiers in Oncology (2021) IF: 6.244
    LncRNA MALAT1 Promotes Tumor Angiogenesis by Regulating MicroRNA-150-5p/VEGFA Signaling in Osteosarcoma: In-Vitro and In-Vivo Analyses

    DOI: 10.3389/fonc.2021.742789

    PMID: 34692524

    Sample: SaOS2 cell,MG63 cell
  12. Food & Function (2022) IF: 6.317
    Sesamin inhibits hypoxia-stimulated angiogenesis via NF-κB p65/HIF-1α/VEGFA signaling pathway in human colorectal cancer

    DOI: 10.1039/D2FO00345G

    Sample: HCT116 cell,SW480 cell
  13. International Journal of Nanomedicine (2022) IF: 6.4
    Self-Assembled Nano-Peptide Hydrogels with Human Umbilical Cord Mesenchymal Stem Cell Spheroids Accelerate Diabetic Skin Wound Healing by Inhibiting Inflammation and Promoting Angiogenesis

    DOI: 10.2147/IJN.S363777

    Sample: hUC-MSCs
  14. INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022) IF: 6.51
    Efficient Delivery of VEGF-A mRNA for Promoting Diabetic Wound Healing via Ionizable Lipid Nanoparticles

    DOI: 10.1016/j.ijpharm.2022.122565

    Sample: Human Umbilical Vein Endothelial Cells (HUVECs)
  15. Cancers (2022) IF: 6.575
    Homo and Heterotypic Cellular Cross-Talk in Epithelial Ovarian Cancer Impart Pro-Tumorigenic Properties through Differential Activation of the Notch3 Pathway

    DOI: 10.3390/cancers14143365

    PMID: 35884426

    Sample: SNFT cell
  16. Acta Biomaterialia (2019) IF: 6.638
    A collagen scaffold loaded with human umbilical cord-derived mesenchymal stem cells facilitates endometrial regeneration and restores fertility

    DOI: 10.1016/j.actbio.2019.05.012

    PMID: 31075515

    Sample: Cell culture supernatant
  17. Stem Cell Research & Therapy (2022) IF: 6.832
    Therapeutic effect of adipose stromal vascular fraction spheroids for partial bladder outlet obstruction induced underactive bladder

    DOI: 10.1186/s13287-022-02739-w

    PMID: 35139904

    Sample: Human umbilical endothelial cells (HUVEC)
  18. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022) IF: 5.062
    An effective VEGF-siRNA delivery via folic acid decorated and pegylated silica nanoparticles

    DOI: 10.1016/j.jddst.2022.103828

    Sample: MDA-MD-231 cell,HeLa cell
  19. iScience (2022) IF: 5.458
    GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis

    DOI: 10.1016/j.isci.2022.104509

    PMID: 35733790

    Sample: HEMECs
  20. INDUSTRIAL CROPS AND PRODUCTS (2022) IF: 5.645
    Preparation and evaluation of photoprotective kenaf seed oil nanocarriers-based cream of tocotrienol-rich fraction

    DOI: 10.1016/j.indcrop.2022.115164

    Sample: Normal human dermal fibroblasts (NHDF)
  21. Aging-US (2021) IF: 5.682
    MiR-195-5p and miR-205-5p in extracellular vesicles isolated from diabetic foot ulcer wound fluid decrease angiogenesis by inhibiting VEGFA expression

    DOI: 10.18632/aging.203393

    PMID: 34370714

    Sample: HUVEC
  22. Nutrients (2021) IF: 5.719
    Tocotrienol-Rich Vitamin E (Tocovid) Improved Nerve Conduction Velocity in Type 2 Diabetes Mellitus Patients in a Phase II Double-Blind, Randomized Controlled Clinical Trial

    DOI: 10.3390/nu13113770

    PMID: 34836025

    Sample: serum
  23. Nutrients (2021) IF: 5.719
    A Phase IIb Randomized Controlled Trial Investigating the Effects of Tocotrienol-Rich Vitamin E on Diabetic Kidney Disease

    DOI: 10.3390/nu13010258

    PMID: 33477404

    Sample: Serum
  24. Frontiers in Pharmacology (2022) IF: 5.988
    Aconiti lateralis radix praeparata total alkaloids exert anti-RA effects by regulating NF-κB and JAK/STAT signaling pathways and promoting apoptosis.

    DOI: 10.3389/fphar.2022.980229

    Sample: MH7A cell
  25. MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020) IF: 4.102
    Melatonin stimulates VEGF expression in human granulosa-lutein cells: A potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome

    DOI: 10.1016/j.mce.2020.110981

    PMID: 32791190

    Sample: Follicular Fluid
  26. Scientific Reports (2018) IF: 4.122
    Activation of the complement system in an osteosarcoma cell line promotes angiogenesis through enhanced production of growth factors

    DOI: 10.1038/s41598-018-23851-z

    Sample: Cell culture supernatant
  27. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020) IF: 4.192
    Chrysin Inhibits Melanoma Tumor Metastasis via Interfering with the FOXM1/β-Catenin Signaling

    DOI: 10.1021/acs.jafc.0c03123

    PMID: 32797754

    Sample: Cell culture medium
  28. Stem Cell Research & Therapy (2017) IF: 4.211
    Adult human periodontal ligament-derived stem cells delay retinal degeneration and maintain retinal function in RCS rats

    DOI: 10.1186/s13287-017-0731-y

    Sample: human periodontal ligament-derived stem cells (hPD
  29. TOXICOLOGY (2016) IF: 4.221
    NLRC5 promotes cell proliferation via regulating the AKT/VEGF-A signaling pathway in hepatocellular carcinoma

    DOI: 10.1016/j.tox.2016.06.012

    Sample: Cell culture supernatant
  30. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2021) IF: 4.291
    Comparison of Serum VEGF, IGF-1, and HIF-1α Levels in Children with Autism Spectrum Disorder and Healthy Controls

    DOI: 10.1007/s10803-020-04820-w

    PMID: 33389301

    Sample: Serum
  31. Cancer Biomarkers (2021) IF: 4.388
    The expression and diagnostic value of serum levels of EphA2 and VEGF-A in patients with colorectal cancer

    DOI: 10.3233/CBM-201745

    PMID: 34092605

    Sample: Serum
  32. International Journal of Nanomedicine (2019) IF: 4.471
    Anti-Angiogenic Activity Of Bevacizumab-Bearing Dexamethasone-Loaded PLGA Nanoparticles For Potential Intravitreal Applications

    DOI: 10.2147/IJN.S217038

    Sample: HUVECs cells
  33. Cancer Medicine (2022) IF: 4.711
    LncRNA SPRY4-IT1 facilitates cell proliferation and angiogenesis of glioma via the miR-101-3p/EZH2/VEGFA signaling axis

    DOI: 10.1002/cam4.5517

    Sample: U87 cells,SNB19 cells,U118 cells
  34. MOLECULES (2019) IF: 3.06
    Effect of Diosmin Administration in Patients with Chronic Venous Disorders on Selected Factors Affecting Angiogenesis

    DOI: 10.3390/molecules24183316

    Sample: serum
  35. BIOLOGICAL RESEARCH (2020) IF: 3.092
    REC8 suppresses tumor angiogenesis by inhibition of NF-κB-mediated vascular endothelial growth factor expression in gastric cancer cells

    DOI: 10.1186/s40659-020-00307-1

    PMID: 32958054

    Sample: Cell lysate
  36. JOURNAL OF THERMAL BIOLOGY (2023) IF: 3.189
    Associations among serum VEGF and CGRP levels with the peripheral vascular blood flow of the skin of the hands in women with Fibromyalgia

    DOI: 10.1016/j.jtherbio.2023.103469

    Sample: Serum
  37. LIFE SCIENCES (2018) IF: 3.234
    The relationship of plasma miR-503 and coronary collateral circulation in patients with coronary artery disease

    DOI: 10.1016/j.lfs.2018.06.001

    Sample: Plasma
  38. Journal of Clinical Medicine (2020) IF: 3.303
    Association of rs699947 (−2578 C/A) and rs2010963 (−634 G/C) Single Nucleotide Polymorphisms of the VEGF Gene, VEGF-A and Leptin Serum Level, and Cardiovascular Risk in Patients with Excess Body Mass: A Case–Control Study

    DOI: 10.3390/jcm9020469

    Sample: Serum
  39. BIOORGANIC & MEDICINAL CHEMISTRY (2022) IF: 3.461
    Efficient Delivery of VEGFA mRNA for Promoting Wound Healing via Ionizable Lipid Nanoparticles

    DOI: 10.1016/j.bmc.2022.117135

    Sample: Human Umbilical Vein Endothelial Cells (HUVECs)
  40. MICROVASCULAR RESEARCH (2022) IF: 3.514
    Context dependent role of p53 during the interaction of hepatocellular carcinoma and endothelial cells

    DOI: 10.1016/j.mvr.2022.104374

    PMID: 35523268

    Sample: HepG2 cell
  41. LIFE SCIENCES (2020) IF: 3.647
    Melatonin regulates tumor angiogenesis via miR-424-5p/VEGFA signaling pathway in osteosarcoma

    DOI: 10.1016/j.lfs.2020.118011

    Sample: Cell lysate
  42. JOURNAL OF ETHNOPHARMACOLOGY (2020) IF: 3.69
    Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways

    DOI: 10.1016/j.jep.2020.113039

    PMID: 32497675

    Sample: Serum,Cell culture supernatant
  43. BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
    Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro

    DOI: 10.1016/j.biopha.2019.108706

    PMID: 30844656

    Sample: Wound drainage fluid
  44. MICROVASCULAR RESEARCH (2022) IF: 3.75
    Evaluation of serum vascular endothelial growth factor level and findings of nailfold capillaroscopy by dermatoscope in the differential diagnosis of palmoplantar psoriasis and palmoplantar eczema

    DOI: 10.1016/j.mvr.2022.104441

    PMID: 36195239

    Sample: serum
  45. CELLULAR SIGNALLING (2017) IF: 3.937
    Identification of NCK1 as a novel downstream effector of STAT3 in colorectal cancer metastasis and angiogenesis

    DOI: 10.1016/j.cellsig.2017.04.020

    Sample: Cell culture supernatant
  46. COLLOIDS AND SURFACES B-BIOINTERFACES (2018) IF: 3.997
    The effects of biomimetically conjugated VEGF on osteogenesis and angiogenesis of MSCs (human and rat) and HUVECs co-culture models

    DOI: 10.1016/j.colsurfb.2018.04.060

    Sample: VEGF solution after immobilization
  47. JOURNAL OF MEDICAL VIROLOGY (2020) IF: 2.021
    Comparison of VEGF‐A Values between Pregnant Women with COVID‐19 and Healthy Pregnancies and Its Association with Composite Adverse Outcomes

    DOI: 10.1002/jmv.26631

    Sample: Whole Blood
  48. TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2020) IF: 2.074
    The Prognostic Value of Circulating VEGF-A Level in Patients With Hepatocellular Cancer:

    DOI: 10.1177/1533033820971677

    Sample: plasma
  49. Biomed Research International (2016) IF: 2.134
    Reduced Plasma miR-146a Is a Predictor of Poor Coronary Collateral Circulation in Patients with Coronary Artery Disease

    DOI: 10.1155/2016/4285942

    Sample: Plasma
  50. BMC Ophthalmology (2021) IF: 2.209
    Increased serum concentration of netrin-1 after intravitreal bevacizumab injection: is it a compensatory mechanism to counteract drug side effects?

    DOI: 10.1186/s12886-021-01989-1

    PMID: 34058994

    Sample: Serum
  51. Experimental and Therapeutic Medicine (2022) IF: 2.447
    Sinensetin suppresses angiogenesis in liver cancer by targeting the VEGF/VEGFR2/AKT signaling pathway

    DOI: 10.3892/etm.2022.11287

    PMID: 35493423

    Sample: HepG2/C3A cell
  52. International Journal of Rheumatic Diseases (2021) IF: 2.454
    Serum VEGF-A and VEGFR-1 levels in patients with adult immunoglobulin A vasculitis

    DOI: 10.1111/1756-185X.14115

    PMID: 33890417

    Sample: Serum
  53. International Journal of General Medicine (2016) IF: 2.466
    Thicker carotid intima-media thickness and increased plasma VEGF levels suffered by post-acute thrombotic stroke patients

    DOI: 10.2147/IJGM.S114577

    PMID: 28008280

    Sample: Plasma
  54. BMC Neurology (2022) IF: 2.474
    Changes of biochemical biomarkers in the serum of children with convulsion status epilepticus: a prospective study

    DOI: 10.1186/s12883-022-02686-2

    PMID: 35624413

    Sample: serum
  55. Reproductive Sciences (2020) IF: 2.616
    Maternal Serum VEGF Predicts Abnormally Invasive Placenta Better than NT-proBNP: a Multicenter Case-Control Study

    DOI: 10.1007/s43032-020-00319-y

    PMID: 33025531

    Sample: Serum
  56. INVESTIGATIONAL NEW DRUGS (2019) IF: 2.663
    The rhenium(I)-diselenoether anticancer drug targets ROS, TGF-β1, VEGF-A, and IGF-1 in an in vitro experimental model of triple-negative breast cancers

    DOI: 10.1007/s10637-019-00727-1

    PMID: 30632005

    Sample: Cell culture medium
  57. JOURNAL OF DIABETES AND ITS COMPLICATIONS (2021) IF: 2.852
    Relationship between elevated microRNAs and growth factors levels in the vitreous of patients with proliferative diabetic retinopathy

    DOI: 10.1016/j.jdiacomp.2021.108021

    PMID: 34420810

    Sample: vitreous sample
  58. LIFE SCIENCES (2017) IF: 2.936
    The relationship of plasma decoy receptor 3 and coronary collateral circulation in patients with coronary artery disease

    DOI: 10.1016/j.lfs.2017.09.025

    Sample: Plasma
  59. ACTA DIABETOLOGICA (2019) IF: 2.996
    polymorphisms with diabetic retinopathy in Pakistani population

    DOI: 10.1007/s00592-019-01407-5

    Sample: Serum
  60. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2017) IF: 1.679
    The Antiangiogenesis Effect of Pirfenidone in Wound Healing In Vitro

    DOI: 10.1089/jop.2017.0007

    Sample: Cell culture supernatant
  61. Jornal de Pediatria (2019) IF: 1.689
    Vascular endothelial growth factor and pulmonary hypertension in children with beta thalassemia major

    DOI: 10.1016/j.jped.2018.05.003

    Sample: Serum
  62. THERAPEUTIC APHERESIS AND DIALYSIS (2021) IF: 1.762
    Angiogenic markers predict kidney injury and obstetric complications in women with preeclampsia and pregnancy-related acute kidney injury

    DOI: 10.1111/1744-9987.13633

    PMID: 33533567

    Sample: Serum
  63. International Journal of Ophthalmology (2019) IF: 1.779
    Autophagy: a new mechanism for regulating VEGF and PEDF expression in retinal pigment epithelium cells

    DOI: 10.18240/ijo.2019.04.05

    Sample: ARPE-19 cells
  64. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Expression and predictive value of HIF‑1α and VEGF in patients with burns following treatment

    DOI: 10.3892/etm.2020.9270

    Sample: Serum
  65. Expert Review of Pharmacoeconomics & Outcomes Research (2018) IF: 1.797
    Clinical outcome and prognostic analysis of meningeal carcinomatosis treated by intrathecal chemotherapy

    DOI: 10.1080/14737167.2018.1467269

    Sample: cell
  66. GROWTH FACTORS (2018) IF: 1.8
    Evaluation of the growth factors VEGF-a and VEGF-B in the vitreous and serum of patients with macular and retinal vascular diseases

    DOI: 10.1080/08977194.2018.1477140

    Sample: Serum
  67. Journal of Ophthalmology (2021) IF: 1.909
    Comparison between Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor Levels in Rhegmatogenous Retinal Detachment

    DOI: 10.1155/2021/2688837

    PMID: 34912575

    Sample: serum
  68. OPHTHALMOLOGICA (2020) IF: 1.926
    Apelin-13: A Promising Biomarker for Age-Related Macular Degeneration?

    DOI: 10.1159/000513050

    Sample: serum
  69. Cellular Reprogramming (2021) IF: 1.987
    Comparison of the Cytokine Profile in Mesenchymal Stem Cells from Human Adipose, Umbilical Cord, and Placental Tissues

    DOI: 10.1089/cell.2021.0043

    PMID: 34677101

    Sample: mesenchymal stem cells (MSCs)
  70. Clinical Ophthalmology (2020)
    Vitreous and Serum Concentrations of Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor in Proliferative Diabetic Retinopathy

    DOI: 10.2147/OPTH.S248812

    Sample: vitreous,serum
  71. SAGE Open Medicine (2022)
    The effects of vitamin E on non-proliferative diabetic retinopathy in type 2 diabetes mellitus: Are they sustainable with 12 months of therapy:

    DOI: 10.1177/20503121221095324

    Sample: serum
  72. JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2020) IF: 0.8070
    Serum levels of vasoactive factors in HIV-infected pre-eclamptic women on HAART

    DOI: 10.1080/01443615.2020.1755626

    Sample: serum
  73. Balkan Medical Journal (2018) IF: 0.887
    Serum Angiogenic and Anti-angiogenic Markers in Pregnant Women with Placenta Percreta

    DOI: 10.4274/balkanmedj.2016.1890

    PMID: 28903888

    Sample: Serum
  74. Cutaneous and Ocular Toxicology (2018) IF: 0.888
    Osmolyte taurine induction in UVA exposed human retinal pigment epithelial cells

    DOI: 10.1080/15569527.2018.1465078

    Sample: Cells
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