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QuicKey Pro Rat T(Testosterone)ELISA Kit

Cat.No.:E-OSEL-R0003
Reactivity: Rat

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96T
48T
24T
96T*5
96T*10

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Product Details

Properties

Assay type	Competitive-ELISA
Format	96T/48T/24
Assay time	1.5h
Detection range	0.16-10 ng/mL
Sensitivity	0.07 ng/mL
Sample type &Sample volume	serum and plasma; 50μL
Specificity	This kit recognizes T in samples. No significant cross-reactivity or interference between T and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are < 10%.
Application	This ELISA kit applies to the in vitro quantitative determination of T concentrations in serum and plasma.

Test Principle

This ELISA kit uses the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with Rat T. Samples (or Standards) and Horseradish Peroxidase (HRP) linked antibody specific for Rat T are added to the micro ELISA plate wells. Rat T in samples (or standards) competes with a fixed amount of T on the solid phase supporter for sites on the HRP linked detection antibody specific to T. Excess conjugate and unbound sample or standard are washed from the plate. The substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450±2 nm. The concentration of Rat T in the samples is then determined by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 6 months. After test, the unused wells and reagents should be stored according to the table.

Item	Specifications	Storage
Micro ELISA Plate(Dismountable)	96T: 8 wells ×12 strips 48T: 8 wells ×6 strips 24T: 8 wells ×3 strips 96T*5: 5 plates, 96T	2-8℃, 1 months
Reference Standard	96T: 2 vials 48T/24T: 1 vial 96T*5: 10 vials	2-8℃, use the reconstituted standard within 24h
Concentrated HRP Linked Detection Ab(100×)	96T: 1 vial, 60 μL 48T/24T: 1 vial, 30 μL 96T*5: 5 vials, 60 μL	2-8℃(Protect from light)
Reference Standard & Sample Diluent	96T/48T/24T: 1 vial, 20 mL 96T*5: 5 vials, 20 mL	2-8℃
HRP Linked Ab Diluent	96T/48T/24T: 1 vial, 14 mL 96T*5: 5 vials, 14 mL
Concentrated Wash Buffer(25×)	96T/48T/24T: 1 vial, 30 mL 96T*5: 5 vials, 30 mL
Substrate Reagent	96T/48T/24T: 1 vial, 10 mL 96T*5: 5 vials, 10 mL	2-8℃(Protect from light)
Stop Solution	96T/48T/24T: 1 vial, 10 mL 96T*5: 5 vials, 10 mL	2-8℃
Plate Sealer	96T/48T/24T: 5 pieces 96T*5: 25 pieces
Product Description	1 copy
Certificate of Analysis	1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level T were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level T were tested on 3 different plates, 20 replicates in each plate.

	Intra-assay Precision			Inter-assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (ng/mL)	0.51	1.16	4.19	0.46	1.22	4.60
Standard deviation	0.03	0.06	0.22	0.02	0.07	0.22
CV (%)	5.82	5.07	5.36	5.37	5.48	4.74

Recovery

The recovery of T spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	91-102	96
EDTA plasma(n=8)	86-102	93

Linearity

Samples were spiked with high concentrations of Rat T and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Synonyms	Testosterone，T
Research Area	Signal Transduction, Signal Transduction, Epigenetics and Nuclear Signaling, Developmental Biology

Assay Procedures

Citations

CARBOHYDRATE POLYMERS (2022) IF: 9.381

Butylated starch alleviates polycystic ovary syndrome by stimulating the secretion of peptide tyrosine-tyrosine and regulating faecal microbiota

DOI: 10.1016/j.carbpol.2022.119304
PMID: 35422283	Sample: serum

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022) IF: 7.129

Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats

DOI: 10.1016/j.ecoenv.2022.114249
PMID: 36323150	Sample: testis

Oxidative Medicine and Cellular Longevity (2022) IF: 7.31

Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats

DOI: 10.1155/2022/2113293
	Sample: serum

Antioxidants (2022) IF: 7.675

Kelulut Honey Ameliorates Oestrus Cycle, Hormonal Profiles, and Oxidative Stress in Letrozole-Induced Polycystic Ovary Syndrome Rats

DOI: 10.3390/antiox11101879
PMID: 36290602	Sample: serum

SCIENCE OF THE TOTAL ENVIRONMENT (2021) IF: 7.963

Effects of acute exposure to microcystins on hypothalamic-pituitary-adrenal (HPA), -gonad (HPG) and -thyroid (HPT) axes of female rats

DOI: 10.1016/j.scitotenv.2021.145196
PMID: 34030373	Sample: Serum

International Journal of Nanomedicine (2021) IF: 6.4

Development and Evaluation of Curcumin Encapsulated Self-assembled Nanoparticles as Potential Remedial Treatment for PCOS in a Female Rat Model

DOI: 10.2147/IJN.S302161
PMID: 34531655	Sample: serum

BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53

Diacerein ameliorates letrozole-induced polycystic ovarian syndrome in rats

DOI: 10.1016/j.biopha.2022.112870
PMID: 35367769	Sample: serum

Oxidative Medicine and Cellular Longevity (2021) IF: 6.543

Curcumin in Combination with Aerobic Exercise Improves Follicular Dysfunction via Inhibition of the Hyperandrogen-Induced IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in PCOS-Like Rats

DOI: 10.1155/2021/7382900
	Sample: serum

ENVIRONMENTAL POLLUTION (2020) IF: 6.793

Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury

DOI: 10.1016/j.envpol.2020.113911
PMID: 31923814	Sample: Tissue homogenate

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2022) IF: 5.011

Acetate: A therapeutic candidate against renal disorder in a rat model of polycystic ovarian syndrome

DOI: 10.1016/j.jsbmb.2022.106179
PMID: 36150640	Sample: plasma

LIFE SCIENCES (2022) IF: 5.037

Studies on testicular ultrastructural and hormonal changes in type-2 diabetic rats treated with highly active antiretroviral therapy conjugated silver nanoparticles

DOI: 10.1016/j.lfs.2022.120498
PMID: 35341824	Sample: serum

LIFE SCIENCES (2021) IF: 5.037

Evaluation of maternal high-fat diet and Quercetin-3-O-rutinoside treatment on the reproductive profile of diet naïve male offspring

DOI: 10.1016/j.lfs.2021.119179
PMID: 33577849	Sample: Tissue homogenate

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2021) IF: 5.098

Pathological changes and oxidative stress of the HPG axis in hypothyroid rat

DOI: 10.1530/JME-21-0095
PMID: 34270447	Sample: serum

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017) IF: 5.104

Protective Effects of Fluvastatin on Reproductive Function in Obese Male Rats Induced by High-Fat Diet through Enhanced Signaling of mTOR

DOI: 10.1159/000457881
	Sample: Serum

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2022) IF: 5.19

Dietary myricetin assuages atrazine-mediated hypothalamic-pituitary–testicular axis dysfunction in rats

DOI: 10.1007/s11356-022-23033-5
	Sample: serum,intra-testicular

EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 5.195

Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats

DOI: 10.1016/j.ejphar.2022.175258
PMID: 36096157	Sample: serum

Reproductive Biology and Endocrinology (2021) IF: 5.211

Icariin improves testicular dysfunction via enhancing proliferation and inhibiting mitochondria-dependent apoptosis pathway in high-fat diet and streptozotocin-induced diabetic rats

DOI: 10.1186/s12958-021-00851-9
PMID: 34753504	Sample: serum

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31

Oxidized high-density lipoprotein enhances endocrine disorders and ovarian damage in rats

DOI: 10.1111/jcmm.16197
PMID: 34346538	Sample: serum

Food & Function (2022) IF: 5.396

Lactiplantibacillus plantarum CCFM1019 attenuate polycystic ovary syndrome through butyrate dependent gut–brain mechanism

DOI: 10.1039/D1FO01744F
PMID: 35044398	Sample: serum

Artificial Cells Nanomedicine and Biotechnology (2021) IF: 5.678

Effects of vancomycin linoleic acid nanoparticles on male reproductive indices of Sprague–Dawley rats

DOI: 10.1080/21691401.2021.1968883
	Sample: serum

Aging-US (2021) IF: 5.682

Paeoniflorin attenuates DHEA-induced polycystic ovary syndrome via inactivation of TGF-β1/Smads signaling pathway in vivo

DOI: 10.18632/aging.202564
PMID: 33638949	Sample: Serum

Frontiers in Pharmacology (2022) IF: 5.811

Proteomic Study on the Reproductive Toxicity of Tripterygium Glycosides in Rats

DOI: 10.3389/fphar.2022.888968
PMID: 35668950	Sample: serum

Frontiers in Pharmacology (2021) IF: 5.811

Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway

DOI: 10.3389/fphar.2021.720387
	Sample: serum

Frontiers in Pharmacology (2021) IF: 5.811

Edible Bird’s Nest Supplementation Improves Male Reproductive Parameters of Sprague Dawley Rat

DOI: 10.3389/fphar.2021.631402
	Sample: serum

Frontiers in Pharmacology (2022) IF: 5.988

Andrographolide exerted anti-inflammatory effects thereby reducing sex hormone synthesis in LPS-induced female rats, but had no effect on hormone production in healthy ones.

DOI: 10.3389/fphar.2022.980064
	Sample: serum

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2022) IF: 4.052

Evaluation of testicular torsion management in Ogbomoso, South-Western Nigeria and surgical detorsion-augmented treatment with phytochemical fractions of Corchorus olitorius leaf in experimental rats

DOI: 10.1016/j.sjbs.2022.103495
	Sample: testicular tissue

BIOCHIMIE (2021) IF: 4.079

Rescue effect of sodium acetate in diabetes mellitus-associated testicular dysfunction is accompanied by PCSK9 modulation

DOI: 10.1016/j.biochi.2021.02.004
PMID: 33581194	Sample: Serum

BIOLOGICAL TRACE ELEMENT RESEARCH (2023) IF: 4.081

Therapeutic Potential of Selenium Nanoparticles on Letrozole-Induced Polycystic Ovarian Syndrome in Female Wistar Rats

DOI: 10.1007/s12011-023-03579-2
	Sample: Serum

TOXICOLOGY (2020) IF: 4.099

Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats

DOI: 10.1016/j.tox.2020.152556
PMID: 32758512	Sample: Serum,Tissue homogenate

Journal of Translational Medicine (2020) IF: 4.124

Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis

DOI: 10.1186/s12967-020-02249-4
	Sample: serum

BIOLOGY OF REPRODUCTION (2022) IF: 4.161

Maternal exposure of rats to sodium saccharin during gestation and lactation on male offspring

DOI: 10.1093/biolre/ioac190
PMID: 36219170	Sample: Plasma

Food & Function (2020) IF: 4.171

Lactic acid bacteria alleviate polycystic ovarian syndrome by regulating sex hormone related gut microbiota

DOI: 10.1039/C9FO02554E
PMID: 32441726	Sample: Serum

Frontiers in Pharmacology (2020) IF: 4.225

Wuzi Yanzong Pill—Based on Network Pharmacology and In Vivo Evidence—Protects Against Spermatogenesis Disorder via the Regulation of the Apoptosis Pathway

DOI: 10.3389/fphar.2020.592827
	Sample: serum

Toxin Reviews (2021) IF: 4.266

Benzo-a-pyrene-induced reproductive toxicity was abated in rats co-treated with taurine

DOI: 10.1080/15569543.2021.1949617
	Sample: serum

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2021) IF: 4.31

Bee bread mitigates downregulation of steroidogenic genes, decreased spermatogenesis, and epididymal oxidative stress in male rats fed with high-fat diet

DOI: 10.1152/ajpendo.00093.2021
PMID: 34229480	Sample: serum,testis

JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36

In vivo and in vitro protective effects of the Wuzi Yanzong pill against experimental spermatogenesis disorder by promoting germ cell proliferation and suppressing apoptosis

DOI: 10.1016/j.jep.2021.114443
PMID: 34302943	Sample: serum

TOXICOLOGY LETTERS (2017) IF: 4.374

Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models

DOI: 10.1016/j.toxlet.2017.11.034
	Sample: Serum

Scientific Reports (2022) IF: 4.38

Testicular ultrastructure and hormonal changes following administration of tenofovir disoproxil fumarate-loaded silver nanoparticle in type-2 diabetic rats

DOI: 10.1038/s41598-022-13321-y
PMID: 35688844	Sample: serum

MOLECULES (2021) IF: 4.412

The Physicochemical Characteristics of Gelam Honey and Its Outcome on the Female Reproductive Tissue of Sprague–Dawley Rats: A Preliminary Study

DOI: 10.3390/molecules26113346
	Sample: serum

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2018) IF: 4.414

Sodium acetate and androgen receptor blockade improve gestational androgen excess-induced deteriorated glucose homeostasis and antioxidant defenses in rats: roles of adenosine deaminase and xanthine oxidase activities

DOI: 10.1016/j.jnutbio.2018.08.018
	Sample: plasma

NUTRITION (2022) IF: 4.893

Acetate circumvents impaired metabolic switch in skeletal muscle of letrozole-induced PCOS rat model by suppression of PDK4/NLRP3

DOI: 10.1016/j.nut.2022.111914
	Sample: plasma

Journal of Clinical Medicine (2022) IF: 4.964

Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome

DOI: 10.3390/jcm11195584
PMID: 36233452	Sample: serum

EXPERIMENTAL BIOLOGY AND MEDICINE (2019) IF: 3.005

Candesartan in a rat model of testicular toxicity: New insight on its protective mechanism:

DOI: 10.1177/1535370219842149
	Sample: serum

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020) IF: 3.056

The gut-microbiota-testis axis mediated by the activation of the Nrf2 antioxidant pathway is related to prepuberal steroidogenesis disorders induced by di-(2-ethylhexyl) phthalate

DOI: 10.1007/s11356-020-09854-2
PMID: 32588312	Sample: Serum,Tissue homogenate

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020) IF: 3.056

Synergic effects of aerobic exercise and eugenol supplement on germ cell development and testicular tissue structure in chlorpyrifos-treated animal model

DOI: 10.1007/s11356-020-08222-4
	Sample: serum

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020) IF: 3.056

Kolaviron suppresses dysfunctional reproductive axis associated with multi-walled carbon nanotubes exposure in male rats

DOI: 10.1007/s11356-020-10324-y
PMID: 32812151	Sample: Serum,Tissue homogenate

Reproductive Sciences (2021) IF: 3.06

Reproductive Effects of Nicotinamide on Testicular Function and Structure in Old Male Rats: Oxidative, Apoptotic, Hormonal, and Morphological Analyses

DOI: 10.1007/s43032-021-00647-7
PMID: 34101148	Sample: testicular

BRAIN RESEARCH BULLETIN (2019) IF: 3.103

The role of gonadal hormones in the hypoglossal discharge activity of rats exposed to chronic intermittent hypoxia

DOI: 10.1016/j.brainresbull.2019.04.017
	Sample: serum

BRAIN RESEARCH (2018) IF: 3.125

Intracerebroventricular injection of histamine induces the hypothalamic-pituitary-gonadal axis activation in male rats

DOI: 10.1016/j.brainres.2018.08.020
	Sample: plasma

REPRODUCTIVE TOXICOLOGY (2022) IF: 3.143

Bisphenol A exposure advances puberty onset by changing Kiss1 expression firstly in arcuate nucleus at juvenile period in female rats

DOI: 10.1016/j.reprotox.2022.04.005
PMID: 35429613	Sample: serum

Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2021) IF: 3.168

The Effect of Rooibos (Aspalathus linearis), Honeybush (Cyclopia intermedia) and Sutherlandia (Lessertia frutescens) on Testicular Insulin Signalling in Streptozotocin-Induced Diabetes in Wistar Rats

DOI: 10.2147/DMSO.S285025
	Sample: Plasma

HUMAN & EXPERIMENTAL TOXICOLOGY (2023) IF: 3.247

Thymol co-administration abrogates hexachlorobenzene-induced reproductive toxicities in male rats

DOI: 10.1177/09603271221149201
	Sample: serum

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2022) IF: 3.255

Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats

DOI: 10.1016/j.ygcen.2022.114138
PMID: 36202220	Sample: serum

International Journal of Endocrinology (2022) IF: 3.257

Harmful Consequences of Proton Pump Inhibitors on Male Fertility: An Evidence from Subchronic Toxicity Study of Esomeprazole and Lansoprazole in Wistar Rats

DOI: 10.1155/2022/4479261
PMID: 35529080	Sample: serum

CHEMICO-BIOLOGICAL INTERACTIONS (2019) IF: 3.407

Very low dose spironolactone protects experimentally-induced polycystic ovarian syndrome from insulin-resistant metabolic disturbances by suppressing elevated circulating testosterone

DOI: 10.1016/j.cbi.2019.108742
	Sample: plasma

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2015) IF: 3.412

Protective effects of metformin on reproductive function in obese male rats induced by high-fat diet

DOI: 10.1007/s10815-015-0506-2
	Sample: Serum

LIFE SCIENCES (2019) IF: 3.448

Protective role of glutamine against cadmium-induced testicular dysfunction in Wistar rats: Involvement of G6PD activity

DOI: 10.1016/j.lfs.2019.117250
PMID: 31899225	Sample: Serum

European Review for Medical and Pharmacological Sciences (2022) IF: 3.507

Spirulina therapeutic potentiality in polycystic ovarian syndrome management using DHEA-induced rat model.

DOI: 10.26355/eurrev_202204_28604
	Sample: serum

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020) IF: 3.606

Ameliorating effects of agomelatine on testicular and epididymal damage induced by methotrexate in rats

DOI: 10.1002/jbt.22445
PMID: 31975554	Sample: Serum

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021) IF: 3.652

Abatement of the dysfunctional hypothalamic–pituitary–gonadal axis due to ciprofloxacin administration by selenium in male rats

DOI: 10.1002/jbt.22741
	Sample: Serum

BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738

Aluminum Chloride–Induced Reproductive Toxicity in Rats: the Protective Role of Zinc Oxide Nanoparticles

DOI: 10.1007/s12011-021-03010-8
	Sample: serum

FOOD AND CHEMICAL TOXICOLOGY (2019) IF: 3.775

Cadmium exposure during prenatal development causes testosterone disruption in multigeneration via SF-1 signaling in rats

DOI: 10.1016/j.fct.2019.110897
PMID: 31654709	Sample: Serum

REPRODUCTION (2021) IF: 3.906

Parents ethanol use impairs ethanol-naive offspring development and reproduction

DOI: 10.1530/REP-20-0316
PMID: 33434152	Sample: Plasma

REPRODUCTION (2021) IF: 3.906

CXCL12 and its receptors regulate granulosa cell apoptosis in PCOS rats and human KGN tumor cells

DOI: 10.1530/REP-20-0451
PMID: 33258800	Sample: Serum,Cell culture supernatant(ovarian granulosa c

Scientific Reports (2020) IF: 3.998

Reproductive effects of subchronic exposure to acetamiprid in male rats

DOI: 10.1038/s41598-020-65887-0
PMID: 32488017	Sample: Plasma,Tissue homogenate

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2020) IF: 2.05

Spironolactone reversed hepato-ovarian triglyceride accumulation caused by letrozole-induced polycystic ovarian syndrome: tissue uric acid—a familiar foe

DOI: 10.1007/s00210-020-01809-1
	Sample: plasma

INTEGRATIVE CANCER THERAPIES (2020) IF: 2.379

Ginkgo biloba Extract Attenuates Methotrexate-Induced Testicular Injury in Rats: Cross-talk Between Oxidative Stress, Inflammation, Apoptosis, and miRNA-29a Expression:

DOI: 10.1177/1534735420969814
	Sample: Serum

Experimental and Therapeutic Medicine (2018) IF: 2.447

Analysis of gene expression and functional changes of adrenal gland in a rat model of kidney yang deficiency syndrome treated with Sini decoction

DOI: 10.3892/etm.2018.6521
PMID: 30214533	Sample: Serum

International Journal of Environmental Research and Public Health (2019) IF: 2.468

Effects of 220 MHz Pulsed Modulated Radiofrequency Field on the Sperm Quality in Rats

DOI: 10.3390/ijerph16071286
	Sample: serum

Journal of Ovarian Research (2019) IF: 2.469

Abnormal expression of HSP70 may contribute to PCOS pathology

DOI: 10.1186/s13048-019-0548-7
	Sample: serum

BMC Complementary and Alternative Medicine (2019) IF: 2.479

Cannabinoid-deficient Benin republic hemp ( Cannabis sativa L.) improves semen parameters by reducing prolactin and enhancing anti-oxidant status

DOI: 10.1186/s12906-019-2541-5
	Sample: plasma

ENVIRONMENTAL TOXICOLOGY (2018) IF: 2.491

Di‐(2‐ethylhexyl) phthalate (DEHP)‐induced testicular toxicity through Nrf2‐mediated Notch1 signaling pathway in Sprague–Dawley rats

DOI: 10.1002/tox.22559
	Sample: Tissue homogenate

Iranian Journal of Basic Medical Sciences (2023) IF: 2.532

Inhibitory effects of Calocybe indica macrofungi on experimental benign prostatic hyperplasia in rats

DOI: 10.22038/IJBMS.2022.64972.14309
	Sample: serum

ENVIRONMENTAL TOXICOLOGY (2019) IF: 2.649

Nano‐selenium attenuates nickel‐induced testosterone synthesis disturbance through inhibition of MAPK pathways in Sprague‐Dawley rats

DOI: 10.1002/tox.22768
	Sample: serum

Journal of Experimental Zoology Part A-Ecological and Integrative Physiology (2022) IF: 2.693

Ameliorative effect of Vitis vinifera (Linn.) seed extract on lead acetate induced oxidative damage on testis and sperm quality in Wistar rats

DOI: 10.1002/jez.2672
	Sample: serum

JOURNAL OF FOOD BIOCHEMISTRY (2021) IF: 2.72

Chlorogenic acid co-administration abates tamoxifen-mediated reproductive toxicities in male rats: An experimental approach

DOI: 10.1111/jfbc.13615
PMID: 33491243	Sample: Serum

ANDROLOGIA (2021) IF: 2.775

Cysteamine mitigates torsion/detorsion-induced reperfusion injury via inhibition of apoptosis, oxidative stress and inflammatory responses in experimental rat model

DOI: 10.1111/and.14243
PMID: 34498746	Sample: serum

ANDROLOGIA (2021) IF: 2.775

Achillea millefolium alleviates testicular damage in paclitaxel-intoxicated rats via attenuation of testicular oxido-inflammatory stress and apoptotic responses

DOI: 10.1111/and.14028
PMID: 33650701	Sample: Serum

Journal of Ginseng Research (2015) IF: 2.815

In vitro and in vivo evaluation of tissue-cultured mountain ginseng on penile erection

DOI: 10.1016/j.jgr.2015.10.003
	Sample: Serum

Andrology (2020) IF: 2.86

Orlistat attenuates obesity‐induced decline in steroidogenesis and spermatogenesis by up‐regulating steroidogenic genes

DOI: 10.1111/andr.12824
	Sample: Tissue homogenate

JOURNAL OF APPLIED TOXICOLOGY (2018) IF: 2.909

Maternal di‐(2‐ethylhexyl) phthalate exposure alters hepatic insulin signal transduction and glucoregulatory events in rat F1 male offspring

DOI: 10.1002/jat.3764
	Sample: Serum

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2019) IF: 2.914

Isolation, characterization, and therapeutic activity of bergenin from marlberry (Ardisia colorata Roxb.) leaf on diabetic testicular complications in Wistar albino rats

DOI: 10.1007/s11356-019-04139-9
PMID: 30648235	Sample: Serum

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2019) IF: 2.914

Attenuation potentials of royal jelly against hydroxyurea-induced infertility through inhibiting oxidation and release of pro-inflammatory cytokines in male rats

DOI: 10.1007/s11356-019-05521-3
	Sample: serum

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019) IF: 2.928

Mitochondria-targeted antioxidant therapy for an animal model of PCOS-IR

DOI: 10.3892/ijmm.2018.3977
PMID: 30431108	Sample: Serum

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019) IF: 2.928

Expression of FKBP52 in the ovaries of PCOS rats

DOI: 10.3892/ijmm.2018.3998
PMID: 30483787	Sample: Serum

Molecular Medicine Reports (2016) IF: 2.952

Curcumin ameliorates high‑fat diet‑induced spermatogenesis dysfunction

DOI: 10.3892/mmr.2016.5712
	Sample: Serum

Journal of Ovarian Research (2020) IF: 2.989

The effect of glutamine on Dehydroepiandrosterone-induced polycystic ovary syndrome rats.

DOI: 10.1186/s13048-020-00650-7
	Sample: Serum

Romanian Journal of Morphology and Embryology (2021) IF: 1.033

Carvacrol treatment opens Kir6.2 ATP-dependent potassium channels and prevents apoptosis on rat testis following ischemia–reperfusion injury model

DOI: 10.47162/RJME.62.1.17
	Sample: serum

Experimental and Therapeutic Medicine (2018) IF: 1.41

Asiatic acid attenuates high-fat diet-induced impaired spermatogenesis

DOI: 10.3892/etm.2017.5672
	Sample: serum

ZYGOTE (2021) IF: 1.442

GPR120 agonist ameliorated insulin resistance and improved ovarian function

DOI: 10.1017/S0967199421000873
PMID: 34879886	Sample: serum

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2015) IF: 1.562

Brain thromboxane A2 via arachidonic acid cascade induces the hypothalamic–pituitary–gonadal axis activation in rats

DOI: 10.1016/j.autneu.2015.02.005
	Sample: Plasma

Systems Biology in Reproductive Medicine (2018) IF: 1.582

Grape seed procyanidins extract attenuates Cisplatin-induced oxidative stress and testosterone synthase inhibition in rat testes

DOI: 10.1080/19396368.2018.1450460
	Sample: serum

JOURNAL OF FOOD BIOCHEMISTRY (2020) IF: 1.662

Ferulic acid influences Nrf2 activation to restore testicular tissue from cadmium‐induced oxidative challenge, inflammation, and apoptosis in rats

DOI: 10.1111/jfbc.13505
	Sample: Serum,Tissue homogenate

JOURNAL OF FOOD BIOCHEMISTRY (2020) IF: 1.662

Berberine mitigates oxidative damage associated with testicular impairment following mercury chloride intoxication

DOI: 10.1111/jfbc.13385
	Sample: Tissue homogenate

Journal of Applied Biomedicine (2018) IF: 1.783

Pre-pregnancy stress suppressed the reproductive systems in parents and changed sex ratio in offspring

DOI: 10.1016/j.jab.2018.08.002
	Sample: Plasma

Evidence-based Complementary and Alternative Medicine (2020) IF: 1.813

Duzhong Butiansu Prescription Improves Heat Stress-Induced Spermatogenic Dysfunction by Regulating Sperm Formation and Heat Stress Pathway

DOI: 10.1155/2020/6723204
PMID: 32184896	Sample: Serum

ANDROLOGIA (2019) IF: 1.84

High dose of standardised extract of Costus afer leaves potentiates cadmium reproductive toxicity in Wistar rats

DOI: 10.1111/and.13360
	Sample: plasma

ANDROLOGIA (2019) IF: 1.84

Effects of N‐nitro L‐arginine methyl ester and α‐tocopherol on testicular oxidative stress caused by exposure to cigarette smoke

DOI: 10.1111/and.13355
	Sample: serum

ANDROLOGIA (2020) IF: 1.951

Selenium attenuates diclofenac‐induced testicular and epididymal toxicity in rats

DOI: 10.1111/and.13669
	Sample: Sperm

Heliyon (2021)

Treatment with acetate during late pregnancy protects dams against testosterone-induced renal dysfunction

DOI: 10.1016/j.heliyon.2021.e05920
	Sample: plasmsa

Toxicology Reports (2021)

Sildenafil augments fetal weight and placental adiponectin in gestational testosterone-induced glucose intolerant rats

DOI: 10.1016/j.toxrep.2021.06.011
	Sample: plasma，placental

Heliyon (2021)

Sildenafil ameliorates leptin resistance and normalizes lipid handling in the hypothalamic and adipose tissues of testosterone-exposed pregnant rats

DOI: 10.1016/j.heliyon.2021.e07574
	Sample: plasma

Veterinary World (2020)

Black soybean tempeh and purple sweet potato improve sperm quality in streptozotocin-induced diabetic rats

DOI: 10.14202/vetworld.2020.2534-2540
	Sample: serum

International Journal of Fertility & Sterility (2017)

Aluminium-Induced Oxidative Stress, Apoptosis and Alterations in Testicular Tissue and Sperm Quality in Wistar Rats: Ameliorative Effects of Curcumin

DOI: 10.22074/ijfs.2017.4859
	Sample: plasma

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