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Cardiovascular diseases (CVDs) as the leading cause of death worldwide involve the disorders of the heart and blood vessels. Investigation into the cardiovascular system will help scientists better understand the underlying mechanisms during diseases development. A lot of studies will be required to create effective treatments against cardiovascular diseases (CVDs).
P53 is a tumor suppressor protein that regulates the expression of a variety of genes, including apoptosis, growth inhibition, inhibition of cell cycle progression, differentiation and acceleration of DNA repair.
Adenylate-activated protein kinase (AMPK) is a key molecule in the regulation of bioenergy metabolism which exists as a heterotrimeric complex consist of an α-catalytic subunit, a β-regulatory subunit, and a γ-regulatory the composition of subunits.