Elabscience Ready-to-Use Antibodies

Recombinant Proteins

Recombinant protein is a manipulated form of protein produced through recombinant DNA technology. By inserting the DNA encoding the protein into bacterial or mammalian cells, we can get quantities of target proteins after amplifying expression and purification. Elabscience® offers a diverse selection of more than 4000 proteins for your research, including cytokines, growth factors, immune checkpoint proteins, CD antigen, FC Receptor, enzymes, hormone, etc.

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Elabscience® also provides Protein Expression and Purification Services, Peptide Synthesis Service to help you obtain the protein that is not in the catalog.

Advantages of Elabscience® Recombinant Protein

Advantages of Elabscience<sup>® Recombinant Protein
  • Active Proteins
  • Cytokines
  • Immune Checkpoint Proteins

Active Proteins

Elabscience® offers over 1000 different active proteins ready for experimental usage. There are a wide range of biological assay methods to measure the bioacitivity of a recombinant protein, including proliferation assay, cytokine induction assay, chemotaxis assay, cell proliferation assay, enzyme assay, funtional ELISA , etc. The recombinant proteins that validated bioactivity are available for cell culture, drug target research, candidate drugs, structural study, protein-protein interaction study and many other research fields.

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Featured Data

Annexin V
Detection of Apoptotic Camptothecin-treated Jurkat by Annexin V Staining. 

Jurkat were left untrated (left) or treated with 1 μM Camptothecin treated for 4 h (right) and then stained using Annexin V-APC. The combination of Annexin V(PKSH033460), APC labeled allows for the distinction between apoptotic cells (Annexin V-APC positive) and viable cells (unstained).

PKSH033611

Recombinant human IL-6(PKSH033611) was measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 20-100pg/ml.

Immune Checkpoint Proteins

Immune checkpoints are regulators of the immune activation. They consist of stimulatory and inhibitory pathways that maintain self-tolerance and assist with immune response. Stimulatory Immune checkpoints augment immunological responses against pathogens. On the contrary, inhibitory Immune checkpoints negatively regulate T-cell activation. In cancer, immune checkpoint mechanisms are often activated to suppress the nascent anti-tumor immune response, and PD-1, PD-L1, CTLA-4, CD28, OX40 are hot targets for cancer immunotherapy.

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Stimulatory Checkpoint Proteins Inhibitory Checkpoint Proteins OX40 OX40L ? VISTA ICOS ICOSL VISTA HVEM TIM-3 Galectin 9 TIGIT PVR TIGIT Nectin-2 PD-1 PD-L2 PD-1 PD-L1 LIGHT HVEM LAG3 MHCⅠ /MHCⅡ GITR GITRL DR3 TL1A DNAM-1 Nectin-2 DNAM-1 PVR CD96 Nectin-1 CD96 PVR ? PD-L2 ? IDO1 CTLA4 CD86 CTLA4 CD80 CD47 SIRPG CD47 SIRPA BTLA HVEM ? B7-H4 ? B7-H3 ? PD-L1 CD48 2B4 CD40 CD40L CD30 CD30L CD28 CD86 CD28 CD80 CD27 CD70 4-1BB 4-1BBL

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