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Cat.No.:E-AB-F1235B
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Alternate Names | Integrin alpha-V,αV integrin,Vitronectin Receptor,Integrin αV chain,ITGAV |
Swissprot | P43406 |
Gene ID | 16410 |
References |
1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Maxfield SR, et al. 1989. J. Exp. Med. 169:2173. 3. Piali L, et al. 1995. J. Cell Biol. 130:451. |
Form | Liquid |
Clone No. | RMV-7 |
Host | Rat |
Isotype | Rat IgG1, κ |
Isotype Control | Biotin Rat IgG1, κ Isotype Control[HRPN] [Product E-AB-F09823B] |
Reactivity | Mouse |
Application | FCM |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | Biotin |
How to select the appropriate detection channel through the spectrogram?
CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Product Name | Sizes | Price |
PE Anti-Mouse CD51 Antibody[RMV-7] | 50Tests, 100Tests, 100Tests×2 | Check More |
APC Anti-Mouse CD51 Antibody[RMV-7] | 50Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | 50Tests, 100Tests, 100Tests×2 | Check More |
PE Anti-Mouse CD51 Antibody[RMV-7] | 25μg, 100μg | Check More |
APC Anti-Mouse CD51 Antibody[RMV-7] | 25μg, 100μg | Check More |
PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] | 25μg, 100μg | Check More |