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Recombinant Human Cyclophilin D/PPID Protein (His Tag)

Uniprot : Q08752

Cat.No.:PKSH032874
Expression host: E.coli

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Description

Synonyms	Peptidyl-Prolyl Cis-Trans Isomerase D;PPIase D;40 kDa Peptidyl-Prolyl Cis-Trans Isomerase;Cyclophilin-40;CYP-40;Cyclophilin-Related Protein;Rotamase D;PPID;CYP40;CYPD
Species	Human
Expression_host	E.coli
Sequence	Met 1-Ala370
Accession	Q08752
Mol_Mass	43.9 kDa
AP_Mol_Mass	40 kDa
Tag	N-His & C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
Reconstitution	Not Applicable

Background

Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.

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