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Recombinant Human Cathepsin B/CTSB Protein (His Tag)

Uniprot : P07858
  • Cat.No.:PKSH032179

  • Expression host: HEK293 Cells

To Purchase PKSH032179

  • 10μg
  • 50μg
Price: $223


Synonyms Cathepsin B;APP Secretase;APPS;Cathepsin B1;CTSB;CPSB
Species Human
Expression_host HEK293 Cells
Sequence Arg18-Ile339
Accession AAH10240.1
Mol_Mass 36.9 kDa
AP_Mol_Mass 34&38-50 kDa
Tag C-His


Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, 8% Sucrose, 0.05% Tween 80, pH7.4.
Reconstitution Not Applicable


Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes



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