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Recombinant Human Cathepsin L/CTSL Protein (His Tag)

Uniprot : P07711
  • Cat.No.:PKSH032182

  • Expression host: Human Cells

To Purchase PKSH032182

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  • 10µg
  • 50µg
Price: $223
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Description

Synonyms Cathepsin L1; Major Excreted Protein; MEP; CTSL1; CTSL
Species Human
Expression_host Human Cells
Sequence Thr18-Val333
Accession P07711
Mol_Mass 36.9 kDa
AP_Mol_Mass 34 kDa
Tag C-6His

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per µg as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Formulation Supplied as a 0.2 μM filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
Reconstitution Not Applicable

Background

Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.

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