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Recombinant Human PPIase/FKBP7 Protein (aa 24-222, His Tag)

Uniprot : Q9Y680

Cat.No.:PKSH032878
Expression host: HEK293 Cells

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Description

Synonyms	Peptidyl-Prolyl Cis-Trans Isomerase FKBP7;PPIase FKBP7;23 kDa FK506-Binding Protein;23 kDa FKBP;FKBP-23;FK506-Binding Protein 7;FKBP-7;Rotamase;FKBP7;FKBP23
Species	Human
Expression_host	HEK293 Cells
Sequence	Gln24-Leu222
Accession	Q9Y680
Mol_Mass	23.9 kDa
AP_Mol_Mass	25-32 kDa
Tag	C-His

Properties

Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin level	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM CaCl₂, 10% Glycerol, pH 7.5.
Reconstitution	Not Applicable

Background

Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.

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