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Recombinant Mouse CD147/Basigin Protein (aa 22-325, His Tag)

  • Cat.No.:PKSM041223

  • Expression host: HEK293 Cells

To Purchase PKSM041223

Size:
  • 10µg
  • 50µg
Price: $111
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Description

Synonyms Basigin;Basic immunoglobulin superfamily;HT7 antigen;Membrane glycoprotein gp42;CD147;Bsg;AI115436;AI325119;EMMPRIN;HT-7
Species Mouse
Expression_host HEK293 Cells
Sequence Ala22-Arg325
Accession P18572
Mol_Mass 34.1 kDa
AP_Mol_Mass 45-60 kDa
Tag C-His

Properties

Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin level < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.

Background

Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.

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