SARS-CoV-2 ELISA Kit

SARS-CoV-2 is a virus that can cause severe acute respiratory failure and spread on a large scale in the population. Its existence and transmission pose a serious threat to human life and physical health, and it has caused the most serious public health incident in the world in recent years.

SARS-CoV-2 has several structural proteins including spike (S), envelope (E), membrane (M) and nucleocapsid (N). The spike protein (S) contains a receptor-binding domain (RBD), which is responsible for recognizing the cell surface receptor, angiotensin converting enzyme-2 (ACE2). It is found that the RBD of the SARS-CoV-2 S protein strongly interacts with the human ACE2 receptor leading to endocytosis into the host cells of the deep lung and viral replication.

To effectively and quickly screen out SARS-CoV-2 asymptomatic, severely ill patients and recovered patients among large-scale populations, the application of molecular biology and immunology technology is particularly important. In order to help the SARS-CoV-2 research, Elabscience has developed 9 types of SARS-CoV-2 related antigen and antibody ELISA kits, which can meet customer research needs.

The neutralizing antibody detection is mainly for the detection of neutralizing epitope, spike protein S1 RBD antibodies to SARS-CoV-2, which aims to test whether recovered patients and vaccinators have immunity to SARS-CoV-2.

Antigen detection includes the quantitative detection of SARS-CoV-2 spike protein S1 RBD and SARS-CoV-2 nucleocapsid protein, which is mainly used for screening asymptomatic infections and patients with mild or severe illness.

Antibody detection includes five types: SARS-CoV-2 spike protein IgM, SARS-CoV-2 spike protein IgG, SARS-CoV-2 spike protein total antibody, SARS-CoV-2 nucleocapsid protein IgM, SARS-CoV-2 nucleocapsid protein IgG. The qualitative detection of antibodies is mainly used for screening asymptomatic infections, mild and severe patients, and recovered patients, especially the spike protein total antibody test, which can screen patients at different stages of infection and minimize false negatives cases.