Alternate Names	Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα
Swissprot	P16871
Gene ID	3575
References	1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125. 2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503. 3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610. 4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403. 5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707. 6. Liu W, et al. 2006. J. Exp. Med. 203:1701.

Product Details

Form	Liquid
Clone No.	A019D5
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	Biotin Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09793B]
Reactivity	Human
Application	FCM
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Biotin

How to select the appropriate detection channel through the spectrogram?

Background

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
FITC Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
PE Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
APC Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® Violet 450 Anti-Human CD127/IL-7RA Antibody[A019D5]	20Tests, 100Tests, 100Tests×2	Check More

Reviews/Q&A

Show all
Reviews
Q&A

... Show All Show Less

*Product Name:
*Catalog Number:
*Name:
*Email:
*Message:
*Country:
*When will you use it?	Within 1 month In 2 to 3 month In 4 to 6 month 6 months later
*Captcha:	Click to load Captcha