Form	Liquid
Host	Goat
Reactivity	Rabbit
Application	WB,IHC,ELISA (See the Application Description)
Storage Buffer	PBS with 0.02% sodium azide,1% protective protein and 50% glycerol
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at -20℃. Avoid freeze / thaw cycles. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	HRP

How to select the appropriate detection channel through the spectrogram?

Protocols & Troubleshootings

Related Protocols	Staining Intracellular Antigens for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Citations

Aging-US (2020) IF: 4.831

K63 ubiquitin chains target NLRP3 inflammasome for autophagic degradation in ox-LDL-stimulated THP-1 macrophages

DOI: 10.18632/aging.102710
PMID: 32003754	Sample: Cell Culture Supernatant

Frontiers in Molecular Biosciences (2021) IF: 5.246

X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca2+ Influx in Rat Brain Microvascular Endothelial Cells

DOI: 10.3389/fmolb.2021.646730
	Sample: Bmec

Frontiers in Cellular and Infection Microbiology (2022) IF: 6.073

Sodium houttuyfonate effectively treats acute pulmonary infection of Pseudomonas aeruginosa by affecting immunity and intestinal flora in mice

DOI: 10.3389/fcimb.2022.1022511
	Sample: Lung

Food Science and Human Wellness (2021) IF: 5.154

Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway

DOI: 10.1016/j.fshw.2021.04.008
	Sample: Colon

Aging-US (2020) IF: 4.831

The endothelial nitric oxide synthase/cyclic guanosine monophosphate/protein kinase G pathway activates primordial follicles

DOI: 10.18632/aging.202235
PMID: 33291075	Sample: Cell Culture Supernatant

Frontiers in Microbiology (2022) IF: 6.064

E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway

DOI: 10.3389/fmicb.2022.944101
PMID: 35992663	Sample: Corneal Tissue,Human Corneal Epithelial Cell (Hcec

MOLECULAR NUTRITION & FOOD RESEARCH (2022) IF: 6.575

Effect of Xuanwei Ham Proteins with Different Ripening Periods on Lipid Metabolism, Oxidative Stress and Gut Microbiota in Mice

DOI: 10.1002/mnfr.202101020
	Sample: Liver Tissue

CHEMICO-BIOLOGICAL INTERACTIONS (2022) IF: 5.168

The involvement of gut microbiota in the anti-tumor effect of carnosic acid via IL-17 suppression in colorectal cancer

DOI: 10.1016/j.cbi.2022.110080
PMID: 35926579	Sample: Colorectal Tissue

Frontiers in Pharmacology (2022) IF: 5.811

Calf Thymus Polypeptide Restrains the Growth of Colorectal Tumor via Regulating the Intestinal Microbiota-Mediated Immune Function

DOI: 10.3389/fphar.2022.898906
PMID: 35662701	Sample: Colorectum,Heart,Liver,Spleen,Kidney,,Lung Specime

CARBOHYDRATE POLYMERS (2019) IF: 6.044

Studies on characteristics and anti-diabetic and -nephritic effects of polysaccharides isolated from Paecilomyces hepiali fermentation mycelium in db/db mice

DOI: 10.1016/j.carbpol.2019.115766
PMID: 31952583	Sample: Tissue Homogenate

Frontiers in Cardiovascular Medicine (2022) IF: 6.05

Parathyroid Hormone Promotes Human Umbilical Vein Endothelial Cell Migration and Proliferation Through Orai1-Mediated Calcium Signaling

DOI: 10.3389/fcvm.2022.844671
PMID: 35369318	Sample: Huvecs

Frontiers in Cardiovascular Medicine (2021) IF: 6.05

Oral Supplementation With Butyrate Improves Myocardial Ischemia/Reperfusion Injury via a Gut-Brain Neural Circuit

DOI: 10.3389/fcvm.2021.718674
PMID: 34631821	Sample: Heart Tissue

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020) IF: 5.162

Calf thymus polypeptide improved hematopoiesis via regulating colony-stimulating factors in BALB/c mice with hematopoietic dysfunction

DOI: 10.1016/j.ijbiomac.2020.03.041
	Sample: K562 Cell,Chrf Cell,Primary Bone Marrow Cell

EUROPEAN JOURNAL OF PHARMACOLOGY (2023) IF: 5.195

Puerarin protects against sepsis-associated encephalopathy by inhibiting NLRP3/Caspase-1/GSDMD pyroptosis pathway and reducing blood-brain barrier damage

DOI: 10.1016/j.ejphar.2023.175616
	Sample: Brain Tissue,Ht22 Cell

Frontiers in Pharmacology (2021) IF: 5.811

The Protection of Crocin Against Ulcerative Colitis and Colorectal Cancer via Suppression of NF-κB-Mediated Inflammation

DOI: 10.3389/fphar.2021.639458
	Sample: Colon Tissue

Molecular and Clinical Oncology (2023)

Stathmin1 promotes lymph node metastasis in hypopharyngeal squamous cell carcinoma via regulation of HIF‑1α/VEGF‑A axis and MTA1 expression

DOI: 10.3892/mco.2023.2617
	Sample: Fadu Cell

International Journal of Ophthalmology (2019) IF: 1.189

Inhibition of LOX-1 alleviates the proinflammatory effects of high-mobility group box 1 in Aspergillus fumigatus keratitis

DOI: 10.18240/ijo.2019.06.03
	Sample: Raw264.7 Cells

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2020) IF: 1.287

Melatonin attenuates AFB1-induced cardiotoxicity via the NLRP3 signalling pathway:

DOI: 10.1177/0300060520952656
	Sample: Cell Lysate

MOLECULAR BIOLOGY (2021) IF: 1.374

A Luciferase-EGFP Reporter System for the Evaluation of DNA Methylation in Mammalian Cells

DOI: 10.1134/S0026893321040099
PMID: 34226765	Sample: 293T Cells

Experimental and Therapeutic Medicine (2019) IF: 1.448

Effect of PI3K/Akt/mTOR signaling pathway on JNK3 in Parkinsonian rats

DOI: 10.3892/etm.2018.7120
PMID: 30783448	Sample: Tissue Homogenate

PHARMACOLOGY (2019) IF: 1.615

Gastrodin Alleviates Vascular Dementia in a 2-VO-Vascular Dementia Rat Model by Altering Amyloid and Tau Levels

DOI: 10.1159/000504056
PMID: 31752010	Sample: Tissue Homogenate

Oncology Letters (2018) IF: 1.664

Dihydroartemisinin triggers c‑Myc proteolysis and inhibits protein kinase B/glycogen synthase kinase 3β pathway in T‑cell lymphoma cells

DOI: 10.3892/ol.2018.9450
	Sample: Cells

JOURNAL OF SPINAL CORD MEDICINE (2019) IF: 1.711

Assessment of the neuroprotective effects of (-)-epigallocatechin-3-gallate on spinal cord ischemia-reperfusion injury in rats

DOI: 10.1080/10790268.2019.1691862
PMID: 31809244	Sample: Tissue

BIOTECHNIC & HISTOCHEMISTRY (2022) IF: 1.718

Cholesterol crystals activate NLRP3 inflammasomes and promote gallstone formation by increasing mucin secretion

DOI: 10.1080/10520295.2022.2036813
PMID: 35227133	Sample: Gallbladder Tissue,Hibepic Biliary Epithelial Cell

Odontology (2020) IF: 1.84

Morpho-functional effects of different universal dental adhesives on human gingival fibroblasts: an in vitro study

DOI: 10.1007/s10266-020-00569-x
PMID: 33211211	Sample: Human Gingival Fibroblasts

HUMAN & EXPERIMENTAL TOXICOLOGY (2018) IF: 1.84

Influence of hypothyroidism on testicular mitochondrial oxidative stress by activating the p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase signaling pathways in rats:

DOI: 10.1177/0960327118781927
	Sample: Tissue Homogenate

Molecular Medicine Reports (2019) IF: 1.851

Ginsenoside Rg5 induces apoptosis in human esophageal cancer cells through the phosphoinositide‑3 kinase/protein kinase B signaling pathway

DOI: 10.3892/mmr.2019.10093
	Sample: Cell Lysate

Molecular Medicine Reports (2019) IF: 1.851

C‑type natriuretic peptide prevents angiotensin II‑induced atrial connexin 40 and 43 dysregulation by activating AMP‑activated kinase signaling

DOI: 10.3892/mmr.2019.10744

Oncology Letters (2019) IF: 1.871

Exosome‑delivered TRPP2 siRNA inhibits the epithelial‑mesenchymal transition of FaDu cells

DOI: 10.3892/ol.2018.9752
	Sample: Fadu Cells

Oncology Letters (2019) IF: 1.871

Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma

DOI: 10.3892/ol.2019.10374
	Sample: Hela Cells

Toxicology Research (2018) IF: 1.89

Roles of ERK1/2 and PI3K/AKT signaling pathways in mitochondria-mediated apoptosis in testes of hypothyroid rats

DOI: 10.1039/C8TX00122G
PMID: 30542605	Sample: Tissue Homogenate

Journal of Ophthalmology (2023) IF: 1.974

Pirfenidone Attenuates the EMT Process and the Secretion of VEGF in TGF-β2-Induced ARPE-19 Cells via Inhibiting the Activation of the NF-κB/Snail Signaling Pathway

DOI: 10.1155/2023/4798071
	Sample: Retinal Pigment Epithelial (Rpe) Cell

Cell Journal (2019) IF: 2.046

Phospholipase-Cγ1 Signaling Protein Down-Regulation by Oligoclonal-VHHs based Immuno-Liposome: A Potent Metastasis Deterrent in HER2 Positive Breast Cancer Cells.

DOI: 10.22074/cellj.2020.6704
	Sample: Skbr3 Cells,Bt-474 Cells,Skbr3 Cells

IET Nanobiotechnology (2023) IF: 2.05

Anionic liposomes prepared without organic solvents for effective siRNA delivery

DOI: 10.1049/nbt2.12117
	Sample: Hela Cell

HUMAN & EXPERIMENTAL TOXICOLOGY (2020) IF: 2.067

SIRT4 prevents excitotoxicity via modulating glutamate metabolism in glioma cells:

DOI: 10.1177/0960327120907142
	Sample: Cell Lysate

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2019) IF: 2.14

Studies on the Neuroprotection of Osthole on Glutamate-Induced Apoptotic Cells and an Alzheimer’s Disease Mouse Model via Modulation Oxidative Stress

DOI: 10.1007/s12010-019-03101-2
	Sample: Cell Lysate

NEUROSCIENCE LETTERS (2019) IF: 2.173

PI3K/Akt signaling pathway may be involved in MCP-1-induced P2X4R expression in cultured microglia and cancer-induced bone pain rats

DOI: 10.1016/j.neulet.2019.02.024
PMID: 30776493	Sample: Tissue Homogenate

NEUROSCIENCE LETTERS (2019) IF: 2.173

Intrathecal administration of SRT1720 relieves bone cancer pain by inhibiting the CREB/CRTC1 signalling pathway

DOI: 10.1016/j.neulet.2019.134623
PMID: 31722235	Sample: Tissue Homogenate

TOXICON (2019) IF: 2.276

Botulinum toxin type A ameliorates adjuvant-arthritis pain by inhibiting microglial activation-mediated neuroinflammation and intracellular molecular signaling

DOI: 10.1016/j.toxicon.2019.12.153
PMID: 32250746	Sample: Tissue Homogenate

International Journal of Endocrinology (2020) IF: 2.299

Peripheral Spexin Inhibited Food Intake in Mice

DOI: 10.1155/2020/4913785
	Sample: Hypothalamus Tissue

MOLECULAR BIOLOGY REPORTS (2021) IF: 2.316

Alteration of gene expression in reactive astrocytes induced by Aβ1-42 using low dose of methamphetamine

DOI: 10.1007/s11033-021-06629-x
PMID: 34374897	Sample: Astrocyte Cell

CURRENT MICROBIOLOGY (2023) IF: 2.343

Inhibitory Effects of Bacillus Coagulans TL3 on the Ileal Oxidative Stress and Inflammation Induced by Lipopolysaccharide in Rats

DOI: 10.1007/s00284-022-03171-2
	Sample: Ileum

Experimental and Therapeutic Medicine (2022) IF: 2.447

Salvianolic acid A promotes mitochondrial biogenesis and function via regulating the AMPK/PGC‑1α signaling pathway in HUVECs

DOI: 10.3892/etm.2022.11412
	Sample: Primary Huvecs

Neural Regeneration Research (2019) IF: 2.472

GLYX-13 pretreatment ameliorates long-term isoflurane exposure-induced cognitive impairment in mice

DOI: 10.4103/1673-5374.264466
	Sample: Hippocampi

JOURNAL OF MEDICINAL FOOD (2022) IF: 2.786

Does Resveratrol Prevent Sevoflurane Toxicity in Newborn Rats?

DOI: 10.1089/jmf.2021.0154
PMID: 35420459	Sample: Brain Tissue

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2021) IF: 2.802

Nicotinamide nucleotide transhydrogenase mutation analysis in Chinese patients with thyroid dysgenesis

DOI: 10.1002/ajmg.a.62493
PMID: 34545694	Sample: Nthy-Ori 3.1 Cell

Chemical Biology & Drug Design (2021) IF: 2.817

Alginate oligosaccharide alleviates senile osteoporosis via the RANKL-RANK pathway in D-galactose-induced C57BL/6J mice

DOI: 10.1111/cbdd.13904
PMID: 34145772	Sample: Femur

Journal of Pain Research (2023) IF: 2.832

The Role of IL-6 and TMEM100 in Lumbar Discogenic Pain and the Mechanism of the Glycine-Serine-Threonine Metabolic Axis: A Metabolomic and Molecular Biology Study

DOI: 10.2147/JPR.S400871
	Sample: Dorsal Root Ganglion (Drg) Tissue,Intervertebral

Molecular Medicine Reports (2022) IF: 2.952

Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects

DOI: 10.3892/mmr.2022.12704
PMID: 35362542	Sample: Colon Tissues,Colorectal Cancer (Crc) Tissue,Ulcer

BEHAVIOURAL BRAIN RESEARCH (2020) IF: 2.977

Non-selective orexin-receptor antagonist attenuates stress-re-stress-induced core PTSD-like symptoms in rats: Behavioural and neurochemical analyses

DOI: 10.1016/j.bbr.2020.113015
PMID: 33212086	Sample: Plasma,Cerebrospinal Fluid

Pharmacological Reports (2021) IF: 3.027

Development and treatment of cognitive inflexibility in sub-chronic stress–re-stress (SRS) model of PTSD

DOI: 10.1007/s43440-020-00198-9
	Sample: Tissue Homogenate

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2023) IF: 3.195

Glycoside combinations of Buyang Huanwu decoction ameliorate atherosclerosis via STAT3, HIF-1, and VEGF

DOI: 10.1007/s00210-023-02389-6
	Sample: Rat Thoracic Aortic Endothelial Cells (Rtaec)

NEUROSCIENCE LETTERS (2022) IF: 3.197

Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice

DOI: 10.1016/j.neulet.2022.136842
PMID: 35995304	Sample: Brain

Animals (2022) IF: 3.231

gga-miR-449b-5p Regulates Steroid Hormone Synthesis in Laying Hen Ovarian Granulosa Cells by Targeting the IGF2BP3 Gene

DOI: 10.3390/ani12192710
PMID: 36230451	Sample: Granulosa Cells (Gcs)

Biomed Research International (2022) IF: 3.246

Electroacupuncture Activates Neuroplasticity in the Motor Cortex and Corticospinal Tract via the mTOR Pathway in a Rat P-MCAO Model.

DOI: 10.1155/2022/3470685
	Sample: Brain

BRAIN RESEARCH (2022) IF: 3.252

Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement

DOI: 10.1016/j.brainres.2022.147958
PMID: 35654119	Sample: Brain

INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 3.361

The role of netrin-1 in the mouse cornea during Aspergillus fumigatus infection

DOI: 10.1016/j.intimp.2019.03.047
PMID: 30952101	Sample: Tissue Homogenate,Cell Lysate

International Journal of Environmental Research and Public Health (2021) IF: 3.39

Assessment of Unstimulated Whole Salivary Tumor Necrosis Factor Alpha (TNF-α) and Cellular Micronuclei Levels in Snuff (Naswar) Users and Non-Users for Early Diagnosis of Oral Squamous Cell Carcinoma

DOI: 10.3390/ijerph18147230
PMID: 34299679	Sample: Saliva

PLACENTA (2021) IF: 3.481

The effect of gestational diabetes on the expression of mitochondrial fusion proteins in placental tissue

DOI: 10.1016/j.placenta.2021.09.015
PMID: 34600274	Sample: Placenta

MICROVASCULAR RESEARCH (2021) IF: 3.514

MiR-221-3p targets HIPK2 to promote diabetic wound healing

DOI: 10.1016/j.mvr.2021.104306
PMID: 34973299	Sample: Huvec

TOXICOLOGY (2019) IF: 3.547

Ethanol increases manganese—Induced spatial learning and memory deficits via oxidative/nitrosative stress induced p53 dependent/independent hippocampal apoptosis

DOI: 10.1016/j.tox.2019.03.001
	Sample: Tissue

Adipocyte (2022) IF: 3.553

Salvianolic acid A promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes through regulation of the AMPK-PGC1α signalling pathway

DOI: 10.1080/21623945.2022.2116790
PMID: 36053001	Sample: 3T3-L1 Adipocytes

LIFE SCIENCES (2020) IF: 3.647

Naringin ameliorates type 2 diabetes mellitus-induced steatohepatitis by inhibiting RAGE/NF-κB mediated mitochondrial apoptosis

DOI: 10.1016/j.lfs.2020.118118
	Sample: Liver,Hepg2 Cell

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021) IF: 3.652

Proanthocyanidins attenuate the high glucose-induced damage of retinal pigment epithelial cells by attenuating oxidative stress and inhibiting activation of the NLRP3 inflammasome

DOI: 10.1002/jbt.22845
PMID: 34338401	Sample: Arpe-19 Cell

CHEMICO-BIOLOGICAL INTERACTIONS (2020) IF: 3.723

Anti-inflammation of Erianin in dextran sulphate sodium-induced ulcerative colitis mice model via collaborative regulation of TLR4 and STAT3

DOI: 10.1016/j.cbi.2020.109089
	Sample: Colons

IMMUNOLOGY AND CELL BIOLOGY (2020) IF: 3.764

Dimethyl itaconate protects against fungal keratitis by activating the Nrf2/HO‐1 signaling pathway

DOI: 10.1111/imcb.12316
	Sample: Cell Culture Supernatant,Tissue Homogenate

JOURNAL OF PHARMACY AND PHARMACOLOGY (2021) IF: 3.765

Gallic acid attenuates isoniazid and rifampicin-induced liver injury by improving hepatic redox homeostasis through influence on Nrf2 and NF-κB signalling cascades in Wistar Rats

DOI: 10.1093/jpp/rgaa048
	Sample: Liver

CELLULAR AND MOLECULAR NEUROBIOLOGY (2019) IF: 3.811

SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5

DOI: 10.1007/s10571-019-00710-7
	Sample: Lumbar Spinal Cords,Ipsilateral L3–L5 Dorsal Root

Stem Cells International (2019) IF: 3.902

PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function

DOI: 10.1155/2019/4686132
	Sample: Bm-Mscs Cells

EXPERIMENTAL CELL RESEARCH (2018) IF: 3.905

A chimeric protein PTEN-L-p53 enters U251 cells to repress proliferation and invasion

DOI: 10.1016/j.yexcr.2018.05.023
	Sample: Hek293T Cells,U251 Cells

ENDOCRINE (2022) IF: 3.925

Acetate restores hypothalamic-adipose kisspeptin status in a rat model of PCOS by suppression of NLRP3 immunoreactivity

DOI: 10.1007/s12020-022-03191-9
PMID: 36114434	Sample: Hypothalamic Tissue And Vat

NEUROTOXICITY RESEARCH (2023) IF: 3.978

Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice

DOI: 10.1007/s12640-023-00637-4
	Sample: Brain

POULTRY SCIENCE (2022) IF: 4.014

The adiponectin receptor agonist, AdipoRon, promotes reproductive hormone secretion and gonadal development via the hypothalamic-pituitary-gonadal axis in chickens

DOI: 10.1016/j.psj.2022.102319
	Sample: Leydig Cell,Swfs

EXPERIMENTAL GERONTOLOGY (2021) IF: 4.032

Polyphenolic-rich Cissus quadrangularis extract ameliorates insulin resistance by activating AdipoR1 in peri-/post-menopausal rats

DOI: 10.1016/j.exger.2021.111681
PMID: 34973346	Sample: Liver

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2022) IF: 4.052

Evaluation of testicular torsion management in Ogbomoso, South-Western Nigeria and surgical detorsion-augmented treatment with phytochemical fractions of Corchorus olitorius leaf in experimental rats

DOI: 10.1016/j.sjbs.2022.103495
	Sample: Testicular Tissue

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2020) IF: 4.101

LINC00473 rescues human bone marrow mesenchymal stem cells from apoptosis induced by dexamethasone through the PEBP1‑mediated Akt/Bad/Bcl‑2 signaling pathway

DOI: 10.3892/ijmm.2020.4788
	Sample: Cell Lysate

ONCOLOGY REPORTS (2023) IF: 4.136

The PTBP1‑NCOA4 axis promotes ferroptosis in liver cancer cells

DOI: 10.3892/or.2023.8482
	Sample: Hep3B Cell-Xenograft,Huh-7 Cell,Hep3B Cell,Hepg2 C

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019) IF: 4.183

Anti-Diabetic Nephropathy Activities of Polysaccharides Obtained from Termitornyces albuminosus via Regulation of NF-κB Signaling in db/db Mice

DOI: 10.3390/ijms20205205
PMID: 31640118	Sample: Tissue Homogenate

GENOMICS (2022) IF: 4.31

CircEML1 facilitates the steroid synthesis in follicular granulosa cells of chicken through sponging gga-miR-449a to release IGF2BP3 expression

DOI: 10.1016/j.ygeno.2022.110540
	Sample: Granulosa Cells (Gcs)

Drug Design Development and Therapy (2023) IF: 4.319

Effects and Potential Mechanism of Zhuyu Pill Against Atherosclerosis: Network Pharmacology and Experimental Validation

DOI: 10.2147/DDDT.S398808
	Sample: Arterial Blood Vessel Tissues

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2022) IF: 4.369

BMSC-EVs overexpressing PD-L1 ameliorate DSS-induced ulcerative colitis in rats by regulating Th17/Treg cell balance through PTEN/PI3K/AKT/mTOR axis

DOI: 10.1111/jgh.15987
	Sample: Colon Tissue

Scientific Reports (2022) IF: 4.38

NLRP3 inflammasome in rosmarinic acid-afforded attenuation of acute kidney injury in mice

DOI: 10.1038/s41598-022-04785-z
PMID: 35079027	Sample: Kidney

JOURNAL OF PERIODONTAL RESEARCH (2022) IF: 4.419

Semaphorin 3A attenuates the hypoxia suppression of osteogenesis in periodontal ligament stem cells

DOI: 10.1111/jre.12973
PMID: 35037251	Sample: Periodontal Ligament Stem Cell (Pdlscs)

BMC CANCER (2022) IF: 4.43

Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers

DOI: 10.1186/s12885-022-09366-x
PMID: 35291954	Sample: Serum -Isolated Exosome

EUROPEAN JOURNAL OF PHARMACOLOGY (2021) IF: 4.432

Gypenoside XLIX loaded nanoparticles targeting therapy for renal fibrosis and its mechanism

DOI: 10.1016/j.ejphar.2021.174501
PMID: 34529980	Sample: Kidney Tissue,Hk2 Cell

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020) IF: 4.556

Isoforsythiaside Attenuates Alzheimer’s Disease via Regulating Mitochondrial Function Through the PI3K/AKT Pathway

DOI: 10.3390/ijms21165687
	Sample: Hippocampus Tissue,U251 Cell

Frontiers in Physiology (2022) IF: 4.566

Long-Term Wi-Fi Exposure From Pre-Pubertal to Adult Age on the Spermatogonia Proliferation and Protective Effects of Edible Bird’s Nest Supplementation

DOI: 10.3389/fphys.2022.828578
	Sample: Testis

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019) IF: 4.658

MicroRNA‐638 inhibits human aortic valve interstitial cell calcification by targeting Sp7

DOI: 10.1111/jcmm.14405
	Sample: Human Aortic Valve Interstitial Cells (Havics)

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019) IF: 4.784

Anti-inflammatory effect of epidermal growth factor conjugated silk fibroin immobilized polyurethane ameliorates diabetic burn wound healing

DOI: 10.1016/j.ijbiomac.2019.09.219
PMID: 31647938	Sample: Serum,Tissue Homogenate

INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932

Hypoxia and Porphyromonas gingivalis-lipopolysaccharide synergistically induce NLRP3 inflammasome activation in human gingival fibroblasts

DOI: 10.1016/j.intimp.2021.107456
PMID: 33588175	Sample: Cell Culture Supernatant

INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932

High-density lipoprotein reduces microglia activation and protects against experimental autoimmune encephalomyelitis in mice

DOI: 10.1016/j.intimp.2022.108566
PMID: 35101849	Sample: Spinal Cord,Bv2 Microglial Cell

LIFE SCIENCES (2021) IF: 5.037

6,7-Dihydroxycoumarin ameliorates crystal-induced necroptosis during crystal nephropathies by inhibiting MLKL phosphorylation

DOI: 10.1016/j.lfs.2021.119193
PMID: 33577856	Sample: Cell Sample

CHEMICO-BIOLOGICAL INTERACTIONS (2021) IF: 5.194

Lysionotin induces apoptosis of hepatocellular carcinoma cells via caspase-3 mediated mitochondrial pathway

DOI: 10.1016/j.cbi.2021.109500
PMID: 33989594	Sample: Cell Sample

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31

Alginate oligosaccharide alleviates D-galactose-induced cardiac ageing via regulating myocardial mitochondria function and integrity in mice

DOI: 10.1111/jcmm.16746
PMID: 34227740	Sample: Heart

Chinese Medicine (2021) IF: 5.455

Systems pharmacology and transcriptomics reveal the mechanisms of Sanhuang decoction enema in the treatment of ulcerative colitis with additional Candida albicans infection

DOI: 10.1186/s13020-021-00487-2
PMID: 34376226	Sample: Colonic Tissue

Aging-US (2022) IF: 5.682

ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function

DOI: 10.18632/aging.204111
PMID: 35680568	Sample: Colorectal Tumor

PHYTOTHERAPY RESEARCH (2021) IF: 5.882

Eleutheroside B-loaded poly (lactic-co-glycolic acid) nanoparticles protect against renal fibrosis via Smad3-dependent mechanism

DOI: 10.1002/ptr.7293
PMID: 34585457	Sample: Kidney,Hk2 Cell

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208

Biophysical Evaluation of Water-Soluble Curcumin Encapsulated in β-Cyclodextrins on Colorectal Cancer Cells

DOI: 10.3390/ijms232112866
	Sample: Sw480 Cells,Hct116 Cells

BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53

Curcumin nano-micelle induced testicular toxicity in healthy rats; evidence for oxidative stress and failed homeostatic response by heat shock proteins 70-2a and 90

DOI: 10.1016/j.biopha.2021.111945
PMID: 34311173	Sample: Cauda Epididymis

Cancers (2021) IF: 6.639

High Antitumor Activity of the Dual Topoisomerase Inhibitor P8-D6 in Breast Cancer

DOI: 10.3390/cancers14010002
	Sample: Mcf-7 Cell,Skbr3 Cell,Mda-Mb-231 Cell,Uf-182 Cell

Nutrients (2022) IF: 6.706

The Antidiabetic Activities of Neocryptotanshinone: Screened by Molecular Docking and Related to the Modulation of PTP1B

DOI: 10.3390/nu14153031
PMID: 35893885	Sample: Liver,Muscle

Nutrients (2023) IF: 6.706

Anti-Obesity Effect of Auricularia delicate Involves Intestinal-Microbiota-Mediated Oxidative Stress Regulation in High-Fat-Diet-Fed Mice

DOI: 10.3390/nu15040872
	Sample: Liver

Nutrients (2022) IF: 6.706

Anti-Gouty Arthritis and Anti-Hyperuricemia Properties of Sanghuangporus vaninii and Inonotus hispidus in Rodent Models

DOI: 10.3390/nu14204421
PMID: 36297105	Sample: Livers

INFLAMMATION RESEARCH (2023) IF: 6.986

HMGB1/TLR4 signaling pathway enhances abdominal aortic aneurysm progression in mice by upregulating necroptosis

DOI: 10.1007/s00011-023-01694-3
	Sample: Aortic Tissues

Journal of Materials Chemistry B (2022) IF: 7.571

Oxidized chondroitin sulfate eye drops ameliorate the prognosis of fungal keratitis with anti-inflammatory and antifungal effects

DOI: 10.1039/D2TB00114D
PMID: 36070420	Sample: Corneas

Cell Reports (2019) IF: 7.815

SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE

DOI: 10.1016/j.celrep.2019.06.002
	Sample: Cell Sample

Frontiers in Immunology (2022) IF: 8.786

Cuproptosis status affects treatment options about immunotherapy and targeted therapy for patients with kidney renal clear cell carcinoma.

DOI: 10.3389/fimmu.2022.954440
	Sample: Hk-2 Cell,Caki-1 Cell,786-O Cell

Nano Research (2016) IF: 8.893

The influence of nanotopography on organelle organization and communication

DOI: 10.1007/s12274-016-1129-3
	Sample: Cell Lysate

BIOMATERIALS (2019) IF: 10.273

MnFe2O4 nanoparticles accelerate the clearance of mutant huntingtin selectively through ubiquitin-proteasome system

DOI: 10.1016/j.biomaterials.2019.119248
	Sample: Neuro 2A Cells

JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435

Effects of iron oxide nanoparticles as T2-MRI contrast agents on reproductive system in male mice

DOI: 10.1186/s12951-022-01291-2
PMID: 35236363	Sample: Testes

MATRIX BIOLOGY (2022) IF: 10.447

RIPK3-MLKL signaling activates mitochondrial CaMKII and drives intrarenal extracellular matrix production during CKD

DOI: 10.1016/j.matbio.2022.08.005
PMID: 35964866	Sample: Kidney Tissue,L929 Cell

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022) IF: 11.161

TEAD4 functions as a prognostic biomarker and triggers EMT via PI3K/AKT pathway in bladder cancer

DOI: 10.1186/s13046-022-02377-3
PMID: 35581606	Sample: T24 Cell,5637 Cell,Tccsup Cell,Sv-Huc1 Cell,Biu-87

Molecular Neurodegeneration (2021) IF: 14.195

Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing

DOI: 10.1186/s13024-021-00485-w
PMID: 34551807	Sample: Brain,293T Cell,N2A Cell

Nature Catalysis (2022) IF: 41.813

Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi

DOI: 10.1038/s41929-022-00762-x
	Sample: Human Umbilical Vein Endothelial Cell

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