Current Position:Home>>Antibodies>>Pathological Antibodies>> Her-2 Monoclonal Antibody
Catalog number:PA6637
Synonyms:Her-2
Reactivity: Human
Applications: IHC-P
Lead Time:Order now, ship in 3 daysWelcome to order from local distributors.
Add to cart Compare Bulk request ManualSize | 3mL/6mL(Ready-to-Use) 100μL/200μL(Concentrated) |
Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
Source | Mouse |
Reactivity | Human |
Application | IHC-P |
Background | HER2 (also known as HER2 / neu, C-erbB2, erbB2 or neu) is a transmembrane receptor tyrosine kinase, which is a carcinogenic gene. Its activation will cause malignant transformation and increase the malignant potential of cells (cell proliferation, invasion, etc.). HER-2 is over expressed in 15-25% of primary breast cancer. HER-2 can also be found in gastrointestinal cancer, gastroesophageal cancer, ovarian cancer, well differentiated endometrial cancer and some salivary duct tumors. HER2-expressed breast cancer is usually associated with estrogen and progesterone receptor negative. Therefore, the poor prognosis is related to the expression of HER2. |