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Human IL-8(Interleukin 8) ELISA Kit

Citations(87)Uniprot : P10145

Cat.No.:E-EL-H6008
Reactivity: Human

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48T
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96T*5
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Product Details

Properties

Assay type	Sandwich-ELISA
Format	96T/48T/24
Assay time	3.5h
Detection range	7.81-500 pg/mL
Sensitivity	4.69 pg/mL
Sample type &Sample volume	serum, plasma and other biological fluids; 100μL
Specificity	This kit recognizes Human IL-8 in samples. No significant cross-reactivity or interference between Human IL-8 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are < 10%.
Application	This ELISA kit applies to the in vitro quantitative determination of Human IL-8 concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-8. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human IL-8 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human IL-8, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human IL-8. You can calculate the concentration of Human IL-8 in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.

Item	Specifications	Storage
Micro ELISA Plate(Dismountable)	96T: 8 wells ×12 strips 48T: 8 wells ×6 strips	-20℃, 12 months
Reference Standard	96T: 2 vials 48T: 1 vial
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 48T: 1 vial, 60 μL	-20℃(Protect from light), 12 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 12 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL
HRP Conjugate Diluent	1 vial, 14 mL
Concentrated Wash Buffer (25×)	1 vial, 30 mL
Substrate Reagent	1 vial, 10 mL	2-8℃(Protect from light)
Stop Solution	1 vial, 10 mL	2-8°C
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human IL-8 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human IL-8 were tested on 3 different plates, 20 replicates in each plate.

	Intra-assay Precision			Inter-assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	20	20	20
Mean (pg/mL)	20.34	60.67	245.62	24.62	56.15	233.52
Standard deviation	1.21	2.80	12.26	1.39	2.80	9.69
CV (%)	5.95	4.62	4.99	5.65	4.99	4.15

Recovery

The recovery of Human IL-8 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type	Range (%)	Average Recovery (%)
Serum(n=8)	87-99	94
EDTA plasma (n=8)	95-102	98
Cell culture media (n=8)	98-106	102

Linearity

Samples were spiked with high concentrations of Human IL-8 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database Links	SwissProt: P10145
Synonyms	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, 3-10C, AMCF-I, K60
Research Area	Cancer, Cardiovascular, Immunology

Assay Procedures

	1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
	2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
	3. Aspirate and wash the plate for 3 times
	4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
	5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
	6. Add 50μL Stop Solution
	7. Read the plate at 450nm immediately. Calculation of the results

Citations

CHEMICO-BIOLOGICAL INTERACTIONS (2021) IF: 5.194

A novel glyceroglycolipid from brown algae Ishige okamurae improve photoaging and counteract inflammation in UVB-induced HaCaT cells

DOI: 10.1016/j.cbi.2021.109737
PMID: 34740599	Sample: Hacat Cells

COLLOIDS AND SURFACES B-BIOINTERFACES (2023) IF: 5.999

Multifunctional barrier membranes promote bone regeneration by scavenging H2O2, generating O2, eliminating inflammation, and regulating immune response

DOI: 10.1016/j.colsurfb.2023.113147
	Sample: Periodontal Ligament Stem Cells (Pdlscs)

ACTA CLINICA BELGICA (2019) IF: 0.96

Interleukin 8 as predictive factor for response to chemotherapy in colorectal cancer patients

DOI: 10.1080/17843286.2019.1680133
	Sample: Serum

TRANSPLANT IMMUNOLOGY (2021) IF: 1.708

miR-1287-5p upregulation inhibits the EMT and pro-inflammatory cytokines in LPS-induced human nasal epithelial cells (HNECs)

DOI: 10.1016/j.trim.2021.101429
PMID: 34139308	Sample: Hnecs Cells

ARCHIVES OF ORAL BIOLOGY (2020) IF: 1.931

Nec-1 attenuates inflammation and cytotoxicity induced by high glucose on THP-1 derived macrophages through RIP1

DOI: 10.1016/j.archoralbio.2020.104858
PMID: 32805637	Sample: Cell Culture Supernatant

Innate Immunity (2019) IF: 2.173

Functional characterisation of Holothuria leucospilota Fas-associated death domain in the innate immune-related signalling pathways:

DOI: 10.1177/1753425919877680
	Sample: Cell Culture Supernatant

INTERNATIONAL DAIRY JOURNAL (2018) IF: 2.201

Glutathione biosynthesis is essential for antioxidant and anti-inflammatory effects of Streptococcus thermophilus

DOI: 10.1016/j.idairyj.2018.08.012
	Sample: Cell Culture Supernatant

BRAZILIAN JOURNAL OF MICROBIOLOGY (2022) IF: 2.214

In vitro characterization of lactic acid bacterial strains isolated from fermented foods with anti-inflammatory and dipeptidyl peptidase-IV inhibition potential

DOI: 10.1007/s42770-022-00872-5
	Sample: Caco-2 Cell

ACTA ODONTOLOGICA SCANDINAVICA (2019) IF: 2.331

Leptin induces IL-6 and IL-8 expression through leptin receptor Ob-Rb in human dental pulp fibroblasts

DOI: 10.1080/00016357.2018.1536280
PMID: 30600742	Sample: Cell Culture Supernatant

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017) IF: 2.341

Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes

DOI: 10.3892/ijmm.2017.3109
	Sample: Cell Culture Supernatant

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2020) IF: 2.352

A case of asthma with Behcet’s disease: successful treatment with omalizumab and its effects on recurrent aphthous lesions

DOI: 10.1080/08923973.2020.1789656
	Sample: Serum

Journal of Orthopaedic Surgery and Research (2022) IF: 2.359

Circ_0043947 contributes to interleukin 1β-induced injury in chondrocytes by sponging miR-671-5p to up-regulate RTN3 expression in osteoarthritis pathology

DOI: 10.1186/s13018-022-02970-4
PMID: 35331286	Sample: Chondrocytes

MEDICAL MYCOLOGY (2017) IF: 2.377

A fucose specific lectin from Aspergillus flavus induced interleukin-8 expression is mediated by mitogen activated protein kinase p38

DOI: 10.1093/mmy/myw066
	Sample: Human L-132 Cell,Human Monocyte Cell Line (U937),P

CLINICAL RHEUMATOLOGY (2020) IF: 2.394

The clinical value of interleukins-8, -10, and -17 in idiopathic granulomatous mastitis

DOI: 10.1007/s10067-020-04925-8
	Sample: Blood

Experimental and Therapeutic Medicine (2021) IF: 2.447

Mediators of extracellular matrix degradation and inflammation: A new team of possible biomarkers for oral squamous cell carcinoma stage

DOI: 10.3892/etm.2021.10309
PMID: 34194555	Sample: Oral Cancer Tissue

ACTA TROPICA (2018) IF: 2.509

Assessment of chemokine and cytokine signatures in patients with dengue infection: A hospital-based study in Kolkata, India

DOI: 10.1016/j.actatropica.2018.10.017
PMID: 30395811	Sample: Serum

BIOSCIENCE REPORTS (2019) IF: 2.535

Association of IL-6, IL-8, MMP-13 gene polymorphisms with knee osteoarthritis susceptibility in the Chinese Han population

DOI: 10.1042/BSR20181346
PMID: 30635366	Sample: Tissue Homogenate

Clinical Respiratory Journal (2021) IF: 2.57

Adhesion molecules as diagnostic and severity biomarkers in pediatric community-acquired pneumonia

DOI: 10.1111/crj.13334
PMID: 33484111	Sample: Whole Blood,Serum

MICROBIAL PATHOGENESIS (2019) IF: 2.581

Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles

DOI: 10.1016/j.micpath.2019.103719
PMID: 31493501	Sample: Cell Culture Supernatant

Annals of Palliative Medicine (2021) IF: 2.595

The effects of blood purification combined with antibiotics on extravascular lung water index, inflammatory factors, and prognosis of patients with severe acute pancreatitis complicated with acute respiratory distress syndrome.

DOI: 10.21037/apm-21-2168
	Sample: Blood

Annals of Palliative Medicine (2021) IF: 2.595

Effect of probiotics supplementation combined with WeChat platform health management on nutritional status, inflammatory factors, and quality of life in patients with mild-to-moderate ulcerative colitis: a randomized trial.

DOI: 10.21037/apm-21-1056
	Sample: Serum

Dose-Response (2022) IF: 2.623

Immune Cell and Biochemical Biomarkers in Advanced Laryngeal Cancer:

DOI: 10.1177/15593258221115537
	Sample: Serum

Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65

Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6.

DOI: 10.1155/2022/9092311
	Sample: Human Nasal Epithelial Cell (Hnecs)

ONCOLOGY REPORTS (2017) IF: 2.662

PLD4 promotes M1 macrophages to perform antitumor effects in colon cancer cells

DOI: 10.3892/or.2016.5216
	Sample: Macrophage

Food & Function (2016) IF: 2.686

Antidiabetic (type 2) effects of Lactobacillus G15 and Q14 in rats through regulation of intestinal permeability and microbiota

DOI: 10.1039/C6FO00831C
	Sample: Plasma,Serum

EUROPEAN JOURNAL OF DERMATOLOGY (2022) IF: 2.805

Role of the long non-coding RNA, SPRR2C, based on an in vitro psoriatic keratinocyte cell model

DOI: 10.1684/ejd.2022.4247
PMID: 35866915	Sample: Ker-Ct Cell,Hacat Cell

HUMAN & EXPERIMENTAL TOXICOLOGY (2022) IF: 2.903

Fluorometholone inhibits high glucose-induced cellular senescence in human retinal endothelial cells:

DOI: 10.1177/09603271221076107
	Sample: Human Retinal Endothelial Cell

MICROBIAL PATHOGENESIS (2020) IF: 2.914

Curcumin ameliorates Staphylococcus aureus-induced mastitis injury through attenuating TLR2-mediated NF−κB activation

DOI: 10.1016/j.micpath.2020.104054
	Sample: Serum

Oncology Letters (2021) IF: 2.967

Association between the serum concentrations and mutational status of IL‑8, IL‑27 and VEGF and the expression levels of the hERG potassium channel gene in patients with colorectal cancer

DOI: 10.3892/ol.2021.12926
	Sample: Serum

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2019) IF: 3.091

Nisin reduces uterine inflammation in rats by modulating concentrations of pro‐ and anti‐inflammatory cytokines

DOI: 10.1111/aji.13096
	Sample: Serum

Oncology Letters (2022) IF: 3.111

A role for serum cytokines and cell adhesion molecules in the non‑invasive diagnosis of colorectal cancer

DOI: 10.3892/ol.2022.13443
	Sample: Serum

Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2021) IF: 3.168

Inflammatory Biomarkers Levels in T2DM Emirati Patients with Diabetic Neuropathy

DOI: 10.2147/DMSO.S319863
PMID: 34345175	Sample: Serum

FEBS LETTERS (2015) IF: 3.169

The lncRNA MALAT1 protects the endothelium against ox‐LDL‐induced dysfunction via upregulating the expression of the miR‐22‐3p target genes CXCR2 and AKT

DOI: 10.1016/j.febslet.2015.08.046
	Sample: Cell Culture Supernatant

LIFE SCIENCES (2018) IF: 3.234

LncRNA PMS2L2 protects ATDC5 chondrocytes against lipopolysaccharide-induced inflammatory injury by sponging miR-203

DOI: 10.1016/j.lfs.2018.12.020
PMID: 30550887	Sample: Cell Culture Supernatant

PLoS One (2022) IF: 3.24

Clinical characteristics and outcomes of COVID-19 patients in Bali, Indonesia

DOI: 10.1371/journal.pone.0269026
PMID: 35687545	Sample: Serum

Bioengineered (2022) IF: 3.269

Nintedanib ameliorates oxidized low-density lipoprotein -induced inflammation and cellular senescence in vascular endothelial cells

DOI: 10.1080/21655979.2022.2036913
PMID: 35236245	Sample: Huvecs

Bioengineered (2021) IF: 3.269

Apremilast mitigates interleukin (IL)-13-induced inflammatory response and mucin production in human nasal epithelial cells (hNECs)

DOI: 10.1080/21655979.2021.1987818
PMID: 34607526	Sample: Human Nasal Epithelial Cells (Hnecs)

Food & Function (2018) IF: 3.289

Probiotic attributes and prevention of LPS-induced pro-inflammatory stress in RAW264.7 macrophages and human intestinal epithelial cell line (Caco-2) by newly isolated Weissella cibaria strains

DOI: 10.1039/C7FO00469A
	Sample: Caco-2 Cells

CELLULAR IMMUNOLOGY (2019) IF: 3.291

DosR antigen Rv1737c induces activation of macrophages dependent on the TLR2 pathway

DOI: 10.1016/j.cellimm.2019.103947
	Sample: Thp-1 Cells

JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448

Eriodictyol inhibits survival and inflammatory responses and promotes apoptosis in rheumatoid arthritis fibroblast‐like synoviocytes through AKT/FOXO1 signaling

DOI: 10.1002/jcb.28724
	Sample: Rheumatoid Arthritis (Ra) Fibroblast-Like Synovioc

JOURNAL OF NEUROIMMUNOLOGY (2022) IF: 3.478

Association between pro-inflammatory cytokines in cerebrospinal fluid and headache in patients with aneurysmal subarachnoid hemorrhage

DOI: 10.1016/j.jneuroim.2022.577841
PMID: 35279426	Sample: Cerebrospinal Fluid (Csf)

ACS Omega (2021) IF: 3.512

Roflumilast Reduced the IL-18-Induced Inflammatory Response in Fibroblast-Like Synoviocytes (FLS)

DOI: 10.1021/acsomega.0c05281
PMID: 33521454	Sample: Cell Culture Supernatant

Nanoscale Research Letters (2020) IF: 3.578

Nec-1 Attenuates Neurotoxicity Induced by Titanium Dioxide Nanomaterials on Sh-Sy5y Cells Through RIP1

DOI: 10.1186/s11671-020-03300-5
	Sample: Sh-Sy5Y Cell

TOXICOLOGY LETTERS (2017) IF: 3.858

MicroRNA-218 acts by repressing TNFR1-mediated activation of NF-κB, which is involved in MUC5AC hyper-production and inflammation in smoking-induced bronchiolitis of COPD

DOI: 10.1016/j.toxlet.2017.08.079
	Sample: Serum,Cell Culture Supernatant

Annals of Translational Medicine (2021) IF: 3.932

The liver X receptor agonist T0901317 reduces the inflammation of alveolar epithelial cells induced by polyhexamethylene guanidine through inhibition of the NFκB signaling pathway

DOI: 10.21037/atm-21-6501
	Sample: A549 Cell

Annals of Translational Medicine (2022) IF: 3.932

Advanced platelet-rich fibrin promotes the paracrine function and proliferation of adipose-derived stem cells and contributes to micro-autologous fat transplantation by modulating HIF-1α and VEGF

DOI: 10.21037/atm-21-6812
	Sample: Adipose-Derived Stem Cell (Ascs)

INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943

Mammalian Ste20-like kinase 4 inhibits the inflammatory response in Aspergillus fumigatus keratitis

DOI: 10.1016/j.intimp.2020.107021
PMID: 33182037	Sample: Cell Lysate

NEUROGASTROENTEROLOGY AND MOTILITY (2022) IF: 3.96

Somatization is associated with altered serum levels of vitamin D, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome

DOI: 10.1111/nmo.14512
	Sample: Serum

Scientific Reports (2020) IF: 3.998

Validation of Salivary Markers, IL-1β, IL-8 and Lgals3bp for Detection of Oral Squamous Cell Carcinoma in an Indian Population

DOI: 10.1038/s41598-020-64494-3
	Sample: Saliva

Pediatric Obesity (2021) IF: 4

The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial

DOI: 10.1111/ijpo.12872
PMID: 34881510	Sample: Serum

ORAL DISEASES (2022) IF: 4.068

Lycium barbarum polysaccharide-glycoprotein promotes osteogenesis in hPDLSCs via ERK activation

DOI: 10.1111/odi.14409
	Sample: Hpdlscs

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021) IF: 4.223

Occupational exposure of rural workers to pesticides in a vegetable-producing region in Brazil

DOI: 10.1007/s11356-021-12444-5
PMID: 33469792	Sample: Plasma

Frontiers in Pharmacology (2020) IF: 4.225

Sodium Tanshinone II Sulfonate A Ameliorates Hypoxia-Induced Pulmonary Hypertension

DOI: 10.3389/fphar.2020.00687
PMID: 32508639	Sample: Tissue Homogenate

Frontiers in Pharmacology (2020) IF: 4.225

NRF2 -617 C/A Polymorphism Impacts Proinflammatory Cytokine Levels, Survival, and Transplant-Related Mortality After Hematopoietic Stem Cell Transplantation in Adult Patients Receiving Busulfan-Based Conditioning Regimens

DOI: 10.3389/fphar.2020.563321
PMID: 33384597	Sample: Plasma

International Journal of Nanomedicine (2017) IF: 4.3

Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo

DOI: 10.2147/IJN.S134897
	Sample: Cell Culture Supernatant,Serum

DRUG DEVELOPMENT RESEARCH (2021) IF: 4.36

CircTHBS1 facilitates the progression of interstitial cystitis depending on the regulation of miR-139-5p/MFN2 axis

DOI: 10.1002/ddr.21864
PMID: 34368980	Sample: Serum

JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36

Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways

DOI: 10.1016/j.jep.2021.114791
PMID: 34737112	Sample: Mh7A Cell

JOURNAL OF PERIODONTAL RESEARCH (2022) IF: 4.419

Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-κB signaling pathway

DOI: 10.1111/jre.12987
PMID: 35426130	Sample: Human Gingival Fibroblasts (Hgfs)

Nutrients (2020) IF: 4.546

Effect of Lactobacillus acidophilus Fermented Broths Enriched with Eruca sativa Seed Extracts on Intestinal Barrier and Inflammation in a Co-Culture System of an Enterohemorrhagic Escherichia coli and Human Intestinal Cells

DOI: 10.3390/nu12103064
PMID: 33036498	Sample: Cell Culture Supernatant

Frontiers in Genetics (2022) IF: 4.599

ILF2 Contributes to Hyperproliferation of Keratinocytes and Skin Inflammation in a KLHDC7B-DT-Dependent Manner in Psoriasis

DOI: 10.3389/fgene.2022.890624
	Sample: Keratinocytes

International Journal of Environmental Research and Public Health (2022) IF: 4.614

A Randomized Controlled Trial Evaluating the Levels of the Biomarkers hs-CRP, IL-6, and IL-8 in Patients with Temporomandibular Disorder Treated with LLLT, Traditional Conservative Treatment, and a Combination of Both

DOI: 10.3390/ijerph19158987
PMID: 35897358	Sample: Serum

Frontiers in Genetics (2022) IF: 4.772

Downregulation of miRNA miR-1305 and upregulation of miRNA miR-6785-5p may be associated with psoriasis

DOI: 10.3389/fgene.2022.891465
	Sample: Nhek Cell

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019) IF: 4.784

Surface-layer protein from Lactobacillus acidophilus NCFM attenuates tumor necrosis factor-α-induced intestinal barrier dysfunction and inflammation

DOI: 10.1016/j.ijbiomac.2019.06.041
	Sample: Caco-2 Cells

Biomolecules (2021) IF: 4.879

Grape Pomace for Topical Application: Green NaDES Sustainable Extraction, Skin Permeation Studies, Antioxidant and Anti-Inflammatory Activities Characterization in 3D Human Keratinocytes

DOI: 10.3390/biom11081181
PMID: 34439847	Sample: Hacat Keratinocytes

CELL PROLIFERATION (2019) IF: 5.039

Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function

DOI: 10.1111/cpr.12673
	Sample: Caco2 Cells，Ht‐29 Cell

CLINICAL SCIENCE (2020) IF: 5.223

Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function

DOI: 10.1042/CS20200047
PMID: 32219341	Sample: Cell Culture Supernatant

Scientific Reports (2016) IF: 5.228

TLR3-/4-Priming Differentially Promotes Ca 2+ Signaling and Cytokine Expression and Ca 2+ -Dependently Augments Cytokine Release in hMSCs

DOI: 10.1038/srep23103
	Sample: Cell Culture Supernatant

OSTEOARTHRITIS AND CARTILAGE (2018) IF: 5.454

Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis

DOI: 10.1016/j.joca.2018.05.003
	Sample: Serum

JOURNAL OF CELLULAR PHYSIOLOGY (2020) IF: 5.546

Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post-coculture with activated neutrophils

DOI: 10.1002/jcp.29713
PMID: 32385929	Sample: Cell Culture Supernatant

ENVIRONMENTAL POLLUTION (2019) IF: 5.714

Activation of NF-κB pathways mediating the inflammation and pulmonary diseases associated with atmospheric methylamine exposure

DOI: 10.1016/j.envpol.2019.06.059
PMID: 31252119	Sample: Cell Culture Supernatant

Frontiers in Pharmacology (2022) IF: 5.811

Inflammation Affects Liver Function and the Metabolism of Voriconazole to Voriconazole-N-Oxide in Adult and Elderly Patients

DOI: 10.3389/fphar.2022.835871
PMID: 35462904	Sample: Plasma

EBioMedicine (2018) IF: 6.183

The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway

DOI: 10.1016/j.ebiom.2018.11.015
PMID: 30448228	Sample: Cell Culture Supernatant

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208

In Vitro Evaluation of Anti-Inflammatory and Protective Potential of an Extract from Cornus mas L. Fruit against H2O2-Induced Oxidative Stress in Human Skin Keratinocytes and Fibroblasts

DOI: 10.3390/ijms232213755

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208

Fermented Chinese Taiwanofungus camphoratus Extract Ameliorates Psoriasis-Associated Response in HaCaT Cells via Modulating NF-𝜅B and mTOR Pathways

DOI: 10.3390/ijms232314623

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291

Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness

DOI: 10.1016/j.ecoenv.2021.112440
PMID: 34175826	Sample: Hasmcs Cells

Food & Function (2022) IF: 6.317

Whole grain germinated brown rice regulates intestinal immune homeostasis and gastrointestinal hormones in type 2 diabetic patients—a randomized control trial

DOI: 10.1039/D2FO00477A
	Sample: Serum

Pharmaceutics (2022) IF: 6.525

In Vitro Antibacterial and Anti-Inflammatory Activity of Arctostaphylos uva-ursi Leaf Extract against Cutibacterium acnes

DOI: 10.3390/pharmaceutics14091952
PMID: 36145700	Sample: Hacat Cell

Cancers (2023) IF: 6.575

Salivary Interleukin Levels in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia: Findings from a Sri Lankan Study

DOI: 10.3390/cancers15051510
	Sample: Saliva

PHYTOMEDICINE (2022) IF: 6.656

Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro

DOI: 10.1016/j.phymed.2022.154339
PMID: 35870375	Sample: Mh7A Cell

Frontiers in Cell and Developmental Biology (2020) IF: 6.684

EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma

DOI: 10.3389/fcell.2020.574940
PMID: 33363140	Sample: Tissue Homogenate

BRITISH JOURNAL OF CANCER (2022) IF: 7.64

Cathepsin F and Fibulin-1 as novel diagnostic biomarkers for brain metastasis of non-small cell lung cancer

DOI: 10.1038/s41416-022-01744-3
PMID: 35217799	Sample: Serum

Cell Death & Disease (2022) IF: 8.469

A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer

DOI: 10.1038/s41419-022-04734-8
PMID: 35365616	Sample: Hct-116 Cell,Ht-29 Cell

CANCER LETTERS (2022) IF: 8.679

Decreased CXCR2 expression on circulating monocytes of colorectal cancer impairs recruitment and induces Re-education of tumor-associated macrophages

DOI: 10.1016/j.canlet.2022.01.004
PMID: 34999169	Sample: Serum,Thp-1 Cell,Human Circulating Cd14+ Monocytes

Frontiers in Immunology (2022) IF: 8.786

METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m6A-dependent manner

DOI: 10.3389/fimmu.2022.905211
PMID: 35936005	Sample: Rpe Cell

Journal of Neuroinflammation (2022) IF: 9.587

Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell death of neurons in vitro

DOI: 10.1186/s12974-022-02535-6
PMID: 35768823	Sample: Cerebrospinal Fluid (Csf),Peripheral Monocytes

Theranostics (2021) IF: 11.556

A SCID mouse-human lung xenograft model of SARS-CoV-2 infection

DOI: 10.7150/thno.58321
PMID: 33995679	Sample: Tissue Homogenate

CELL (2020) IF: 38.637

Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output

DOI: 10.1016/j.cell.2020.08.009
PMID: 33015716	Sample: Cell Culture Supernatant

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