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Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit

Citations(284)Uniprot : P01375

  • Cat.No.:E-EL-H0109

  • Reactivity: Human
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Manual MSDS

To Purchase E-EL-H0109

Size:
  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $495
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Product Details

Properties

Assay type Sandwich-ELISA
Format 96T/48T/24
Assay time 3.5h
Detection range 7.81-500 pg/mL
Sensitivity 4.69 pg/mL
Sample type &Sample volume serum, plasma and other biological fluids; 100μL
Specificity This kit recognizes Human TNF-α in samples. No significant cross-reactivity or interference between Human TNF-α and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of Human TNF-α concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human TNF-α. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human TNF-α and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human TNF-α, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human TNF-α. You can calculate the concentration of Human TNF-α in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.
ItemSpecificationsStorage
Micro ELISA Plate(Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips 		-20℃, 12 months
Reference Standard 96T: 2 vials
48T: 1 vial
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL 		-20℃(Protect from light), 12 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 12 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL
HRP Conjugate Diluent 1 vial, 14 mL
Concentrated Wash Buffer (25×) 1 vial, 30 mL
Substrate Reagent 1 vial, 10 mL 2-8℃(Protect from light)
Stop Solution 1 vial, 10 mL 2-8°C
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human TNF-α were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human TNF-α were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 24.10 79.50 183.00 22.70 86.50 177.40
Standard deviation 1.50 3.80 9.70 1.20 4.00 7.60
CV (%) 6.22 4.78 5.30 5.29 4.62 4.28

Recovery

The recovery of Human TNF-α spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 86-100 92
EDTA plasma (n=8) 94-106 99
Cell culture media (n=8) 93-107 99

Linearity

Samples were spiked with high concentrations of Human TNF-α and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database LinksSwissProt:   P01375
SynonymsDIF, TNF-alpha, TNFA, TNFSF2
Research AreaCancer, Cardiovascular, Metabolism, Immunology, Signal transduction

Assay Procedures

elisa assay procedure 1

1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
elisa assay procedure 2

2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
elisa assay procedure 3

3. Aspirate and wash the plate for 3 times
elisa assay procedure 4

4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
elisa assay procedure 5

5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
elisa assay procedure 6

6. Add 50μL Stop Solution
elisa assay procedure 7

7. Read the plate at 450nm immediately. Calculation of the results

Citations

  1. Journal of Immunology Research (2021) IF: 4.818
    Moesin Is a Novel Biomarker of Endothelial Injury in Sepsis

    DOI: 10.1155/2021/6695679

    PMID: 33628853

    		 Sample: Cell Culture Supernatant(Hmecs)
  2. Oncotarget (2017) IF: 5.168
    RIP1 is a central signaling protein in regulation of TNF-α/TRAIL mediated apoptosis and necroptosis during Newcastle disease virus infection

    DOI: 10.18632/oncotarget.17970
    Sample: Hela Cell
  3. Cell Death Discovery (2017) IF: 5.241
    Immunohistochemistry Guide for Slide-mounted Paraffin Sections

    DOI: 10.1038/cddiscovery.2016.107
    Sample: Nucleus Pulposus (Np) Cell
  4. Frontiers in Pharmacology (2022) IF: 5.988
    MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation

    DOI: 10.3389/fphar.2022.978587

    PMID: 36091773

    		 Sample: U87 Cell
  5. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo

    DOI: 10.3390/ijms232416134
    Sample: Thp-1 Cells
  6. Genes & Diseases (2022) IF: 7.243
    FTO-mediated m6A modification alleviates autoimmune uveitis by regulating microglia phenotypes via the GPC4/TLR4/NF-κB signaling axis

    DOI: 10.1016/j.gendis.2022.09.008
    Sample: Hmc3 Cells
  7. JOURNAL OF ETHNOPHARMACOLOGY (2023) IF: 5.195
    Comparison study of Beninese and Chinese herbal medicines in treating COVID-19

    DOI: 10.1016/j.jep.2023.116172
    Sample: Beas-2B Cell
  8. BIOINORGANIC CHEMISTRY AND APPLICATIONS (2022) IF: 4.724
    Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer

    DOI: 10.1155/2022/6181448

    PMID: 36248627

    		 Sample: Pc3 Cell,Hsf Cell
  9. PHYTOTHERAPY RESEARCH (2021) IF: 5.882
    Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial

    DOI: 10.1002/ptr.7113

    PMID: 33899292

    		 Sample: Serum
  10. EBioMedicine (2018) IF: 6.183
    The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway

    DOI: 10.1016/j.ebiom.2018.11.015

    PMID: 30448228

    		 Sample: Cell Culture Supernatant
  11. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022) IF: 6.208
    In Vitro Evaluation of Anti-Inflammatory and Protective Potential of an Extract from Cornus mas L. Fruit against H2O2-Induced Oxidative Stress in Human Skin Keratinocytes and Fibroblasts

    DOI: 10.3390/ijms232213755
  12. LIVER INTERNATIONAL (2020) IF: 5.175
    Fontan protein‐losing enteropathy is associated with advanced liver disease and a proinflammatory intestinal and systemic state

    DOI: 10.1111/liv.14375
    Sample: Plasma
  13. Journal of Blood Medicine (2021)
    The Escalation of Osteosarcoma Stem Cells Apoptosis After the Co-Cultivation of Peripheral Blood Mononuclear Cells Sensitized with Mesenchymal Stem Cells Secretome and Colony Stimulating Factor-2 in vitro

    DOI: 10.2147/JBM.S305566
    Sample: Os-Scs Cells
  14. Sport Sciences for Health (2022)
    The effects of aerobic exercise and sertraline on pro-inflammatory indices and amelioration of neurotrophic factors in patients who have undergone CABG

    DOI: 10.1007/s11332-022-00992-3
    Sample: Plasma,Serum
  15. SCIENTIA PHARMACEUTICA (2022)
    Potential and Alternative Bioactive Compounds from Brown Agaricus bisporus Mushroom Extracts for Xerosis Treatment

    DOI: 10.3390/scipharm90040059
    Sample: Hacat Cells
  16. International Journal of Molecular and Cellular Medicine (2020)
    MicroRNAs as Immune Regulators of Inflammation in Children with Epilepsy

    DOI: 10.22088/IJMCM.BUMS.9.3.188
    Sample: Plasma
  17. Sports (2023)
    Long-Term Resistance–Endurance Combined Training Reduces Pro-Inflammatory Cytokines in Young Adult Females with Obesity

    DOI: 10.3390/sports11030054
    Sample: Serum
  18. BMC Research Notes (2020)
    Green coffee extract modifies body weight, serum lipids and TNF-α in high-fat diet-induced obese rats

    DOI: 10.1186/s13104-020-05052-y

    PMID: 32276657

    		 Sample: Serum
  19. Journal of Clinical and Experimental Hepatology (2022)
    Demonstration of gut-barrier dysfunction in early stages of non-alcoholic fatty liver disease: A proof-of-concept study

    DOI: 10.1016/j.jceh.2022.01.006
    Sample: Serum
  20. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi (2021) IF: 0.401
    Oxidative stress index can be a new marker related to disease severity in COVID-19

    DOI: 10.1515/tjb-2021-0013
    Sample: Serum
  21. Neurochemical Journal (2021) IF: 0.48
    Elevated Levels of Activin-A, TNF-Alpha and IL-6 in Acromegaly

    DOI: 10.1134/S181971242103003X
    Sample: Serum
  22. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2022) IF: 0.533
    Clinical efficacy and inflammatory factors in knee osteoarthritis with glucosamine hydrochloride plus meloxicam

    DOI: 10.4314/tjpr.v21i3.30
    Sample: Serum
  23. Revista da Associacao Medica Brasileira (2019) IF: 0.801
    TLR7 mediates increased vulnerability to ischemic acute kidney injury in diabetes

    DOI: 10.1590/1806-9282.65.8.1067

    PMID: 31531603

    		 Sample: Cell Culture Supernatant
  24. Genetic Testing and Molecular Biomarkers (2019) IF: 1.121
    Association of High Mobility Group Box Protein B1 Gene Polymorphisms with Pneumonia Susceptibility and Severity

    DOI: 10.1089/gtmb.2018.0174

    PMID: 30562142

    		 Sample: Plasma
  25. EUROPEAN NEUROLOGY (2020) IF: 1.182
    Effects of Edaravone on Neurological Function and Tumor Necrosis Factor Alpha and Interleukin 8 Levels in Patients with Cerebral Infarction

    DOI: 10.1159/000505776
    Sample: Serum
  26. Experimental and Therapeutic Medicine (2017) IF: 1.261
    Inhibition of miR‑27a suppresses the inflammatory response via the p38/MAPK pathway in intervertebral disc cells

    DOI: 10.3892/etm.2017.5053
    Sample: Cell Culture Supernatant
  27. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY (2019) IF: 1.267
    A label-free and sensitive impedimetric immunosensor for TNF α biomarker detection based on epoxysilane-modified disposable ITO-PET electrode

    DOI: 10.1080/03067319.2019.1679807
    Sample: Immunosensor Construction
  28. EPILEPTIC DISORDERS (2020) IF: 1.276
    HMGB‐1, TLR4, IL‐1R1, TNF‐α, and IL‐1β: novel epilepsy markers?

    DOI: 10.1684/epd.2020.1155
    Sample: Serum
  29. ANZ JOURNAL OF SURGERY (2020) IF: 1.355
    Effect of laparoscopic sleeve gastrectomy on renal function in obese patients

    DOI: 10.1111/ans.15767

    PMID: 32115876

    		 Sample: Serum,Urine
  30. Genetic Testing and Molecular Biomarkers (2020) IF: 1.378
    Correlation Between Single Nucleotide Polymorphisms at the 3′-UTR of the NFKB1 Gene and Acute Kidney Injury in Sepsis

    DOI: 10.1089/gtmb.2019.0222
    Sample: Cell Sample
  31. International Journal of Clinical and Experimental Pathology (2018) IF: 1.396
    MicroRNA-124 alleviates hyperoxia-induced inflammatory response in pulmonary epithelial cell by inhibiting TLR4/NF-κB/CCL2

    PMID: 31938089

    		 Sample: Beas2B Cells
  32. Experimental and Therapeutic Medicine (2018) IF: 1.41
    Role of miR‑589‑3p in human lumbar disc degeneration and its potential mechanism

    DOI: 10.3892/etm.2017.5593
    Sample: Cell Culture Supernatant
  33. Experimental and Therapeutic Medicine (2018) IF: 1.41
    N‑methyl pyrrolidone promotes ankle fracture healing by inhibiting inflammation via suppression of the mitogen‑activated protein kinase signaling pathway

    DOI: 10.3892/etm.2018.5842
    Sample: Peripheral Blood
  34. Experimental and Therapeutic Medicine (2018) IF: 1.41
    Leukocyte depletion does not affect the in vitro healing ability of platelet rich plasma

    DOI: 10.3892/etm.2018.5887
    Sample: Cell Culture Supernatant
  35. Experimental and Therapeutic Medicine (2018) IF: 1.41
    Anti‑inflammatory effect of Resolvin D1 on LPS‑treated MG‑63 cells Corrigendum in /10.3892/etm.2019.8021

    DOI: 10.3892/etm.2018.6721
    Sample: Serum
  36. Experimental and Therapeutic Medicine (2019) IF: 1.448
    Effects of propofol combined with remifentanil anesthesia on the NO, endothelin and inflammatory cytokines in the plasma of patients with liver cirrhosis during the perioperative period

    DOI: 10.3892/etm.2019.7367

    PMID: 30988754

    		 Sample: Plasma
  37. Journal of Burn Care & Research (2019) IF: 1.538
    Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Murine Model: Protective Effect of Cyclosporine-A

    DOI: 10.1093/jbcr/irz029

    PMID: 30926991

    		 Sample: Serum
  38. ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery (2021) IF: 1.538
    Clinical Efficacy and Possible Mechanism of Endoscopic Vidian Neurectomy for House Dust Mite-Sensitive Allergic Rhinitis

    DOI: 10.1159/000511711
    Sample: Serum
  39. MEDICINE (2020) IF: 1.552
    Regulatory role and mechanism of the inhibition of the Mcl-1 pathway during apoptosis and polarization of H37Rv-infected macrophages

    DOI: 10.1097/MD.0000000000022438

    PMID: 33080678

    		 Sample: Cell Culture Supernatant
  40. Molecular Medicine Reports (2017) IF: 1.692
    Tetrahydroxy stilbene glucoside ameliorates H2O2-induced human brain microvascular endothelial cell dysfunction in vitro by inhibiting oxidative stress and inflammatory responses

    DOI: 10.3892/mmr.2017.7225
    Sample: Cell Culture Supernatant
  41. TRANSPLANT IMMUNOLOGY (2021) IF: 1.708
    miR-1287-5p upregulation inhibits the EMT and pro-inflammatory cytokines in LPS-induced human nasal epithelial cells (HNECs)

    DOI: 10.1016/j.trim.2021.101429

    PMID: 34139308

    		 Sample: Hnecs Cells
  42. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Systematically transplanted human gingiva‑derived mesenchymal stem cells regulate lipid metabolism and inflammation in hyperlipidemic mice with periodontitis

    DOI: 10.3892/etm.2019.8256
    Sample: Serum
  43. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF‑α‑mediated osteoclast autophagy

    DOI: 10.3892/etm.2020.8903
    Sample: Cell Culture Supernatant
  44. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Application of dexmedetomidine-assisted intravertebral anesthesia in hip replacement and its influence on T-lymphocyte subsets

    DOI: 10.3892/etm.2020.8869
    Sample: Serum
  45. Evidence-based Complementary and Alternative Medicine (2020) IF: 1.813
    Rhubarb-Aconite Decoction (RAD) Drug-Containing Serum Alleviated Endotoxin-Induced Oxidative Stress Injury and Inflammatory Response in Caco-2 Cells In Vitro

    DOI: 10.1155/2020/5834502

    PMID: 32714409

    		 Sample: Cell Culture Supernatant
  46. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2015) IF: 1.859
    Decreased monocyte subsets and TLR4-mediated functions in patients with acute severe fever with thrombocytopenia syndrome (SFTS)

    DOI: 10.1016/j.ijid.2015.12.009
    Sample: Cell Culture Supernatant
  47. MEDICINE (2019) IF: 1.87
    TLR4/NF-κB signaling pathway gene single nucleotide polymorphisms alter gene expression levels and affect ARDS occurrence and prognosis outcomes

    DOI: 10.1097/MD.0000000000016029
    Sample: Plasma
  48. MEDICINE (2019) IF: 1.87
    A case-control study on the relationship between miRNAs single nucleotide polymorphisms and sepsis risk

    DOI: 10.1097/MD.0000000000016744
    Sample: Serum
  49. MEDICAL SCIENCE MONITOR (2018) IF: 1.894
    Sinomenine Regulates Inflammatory Response and Oxidative Stress via Nuclear Factor kappa B (NF-κB) and NF-E2-Related Factor 2 (Nrf2) Signaling Pathways in Ankle Fractures in Children

    DOI: 10.12659/MSM.910740
    Sample: Serum
  50. MEDICAL SCIENCE MONITOR (2018) IF: 1.894
    Propofol Promotes Ankle Fracture Healing in Children by Inhibiting Inflammatory Response

    DOI: 10.12659/MSM.908592
    Sample: Serum
  51. Brazilian Journal of Psychiatry (2020) IF: 1.904
    Lowered serum cesium levels in schizophrenia: association with immune-inflammatory biomarkers and cognitive impairments

    DOI: 10.1590/1516-4446-2020-0908

    PMID: 32556004

    		 Sample: Serum
  52. MEDICAL SCIENCE MONITOR (2020) IF: 1.918
    Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells

    DOI: 10.12659/MSM.921957

    PMID: 32463805

    		 Sample: Cell Culture Supernatant
  53. Molecular Medicine Reports (2018) IF: 1.922
    The shortening telomere length of T lymphocytes maybe associated with hyper‑function in servere aplastic anemia

    DOI: 10.3892/mmr.2017.8014
    Sample: Cell Culture Supernatant
  54. ARCHIVES OF ORAL BIOLOGY (2020) IF: 1.931
    Nec-1 attenuates inflammation and cytotoxicity induced by high glucose on THP-1 derived macrophages through RIP1

    DOI: 10.1016/j.archoralbio.2020.104858

    PMID: 32805637

    		 Sample: Cell Culture Supernatant
  55. Evidence-based Complementary and Alternative Medicine (2019) IF: 1.984
    In Vitro Immunomodulatory Effect of Food Supplement from Aloe vera

    DOI: 10.1155/2019/5961742

    PMID: 30941196

    		 Sample: Cell Culture Supernatant
  56. Cellular Reprogramming (2021) IF: 1.987
    Comparison of the Cytokine Profile in Mesenchymal Stem Cells from Human Adipose, Umbilical Cord, and Placental Tissues

    DOI: 10.1089/cell.2021.0043

    PMID: 34677101

    		 Sample: Mesenchymal Stem Cells (Mscs)
  57. POULTRY SCIENCE (2019) IF: 2.027
    The effect of different dietary ratios of arginine, methionine, and lysine on the performance, carcass traits, and immune status of turkeys

    DOI: 10.1016/j.psj.2019.10.008

    PMID: 32036960

    		 Sample: Plasma
  58. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2019) IF: 2.041
    Serum irisin level in myocardial infarction patients with or without heart failure

    DOI: 10.1139/cjpp-2018-0736
    Sample: Serum
  59. HUMAN & EXPERIMENTAL TOXICOLOGY (2020) IF: 2.067
    Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users:

    DOI: 10.1177/0960327120930057
    Sample: Plasma
  60. Molecular Medicine Reports (2020) IF: 2.1
    Penehyclidine hydrochloride alleviates lipopolysaccharide‑induced acute respiratory distress syndrome in cells via regulating autophagy‑related pathway

    DOI: 10.3892/mmr.2020.11739

    PMID: 33300058

    		 Sample: Cell Culture Supernatant
  61. AUTOIMMUNITY (2020) IF: 2.125
    Auto-reactivity against gut bacterial peptides in patients with late-onset diabetes

    DOI: 10.1080/08916934.2020.1818232

    PMID: 32924613

    		 Sample: Serum
  62. International Journal of General Medicine (2022) IF: 2.145
    Correlation of Inflammation and Coagulation Markers with the Incidence of Deep Vein Thrombosis in Cancer Patients with High Risk of Thrombosis

    DOI: 10.2147/IJGM.S372038

    PMID: 35898299

    		 Sample: Plasma
  63. Sleep and Breathing (2020) IF: 2.162
    Intermittent hypoxia induces tumor immune escape in murine S180 solid tumors via the upregulation of TGF-β 1 in mice

    DOI: 10.1007/s11325-020-02166-2

    PMID: 32840731

    		 Sample: Tissue Homogenate
  64. Biomed Research International (2019) IF: 2.197
    Nigella sativa Oil Mouth Rinse Improves Chemotherapy-Induced Oral Mucositis in Patients with Acute Myeloid Leukemia

    DOI: 10.1155/2019/3619357
    Sample: Salivary
  65. APMIS (2019) IF: 2.225
    Autoantibodies to a specific peptide epitope of human Hsp60 (ATVLA) with homology to Helicobacter pylori HspB in H. pylori‐infected patients

    DOI: 10.1111/apm.12925
    Sample: Cell Culture Supernatant
  66. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2020) IF: 2.251
    Heme is involved in the systemic inflammatory response following radiofrequency ablation of hepatic hemangiomas

    DOI: 10.1097/MEG.0000000000001636
    Sample: Serum
  67. INTERNATIONAL UROLOGY AND NEPHROLOGY (2022) IF: 2.266
    Evaluation of malnutrition and inflammation after total parathyroidectomy in patients on maintenance dialysis

    DOI: 10.1007/s11255-022-03436-6
    Sample: Serum
  68. Biomed Research International (2020) IF: 2.276
    Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial

    DOI: 10.1155/2020/8748934
    Sample: Serum
  69. Trials (2021) IF: 2.279
    Effect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial

    DOI: 10.1186/s13063-021-05529-6

    PMID: 34521466

    		 Sample: Blood
  70. Obesity Research & Clinical Practice (2021) IF: 2.288
    Roles and mechanisms of NRG1 in modulating the pathogenesis of NAFLD through ErbB3 signaling in hepatocytes (NRG1 modulates NAFLD through ErbB3 signaling)

    DOI: 10.1016/j.orcp.2021.01.003

    PMID: 33541789

    		 Sample: Cell Culture Supernatant
  71. BMC Cardiovascular Disorders (2022) IF: 2.298
    The abnormal distribution of peripheral B1 cells and transition B cells in patients with idiopathic dilated cardiomyopathy: a pilot study

    DOI: 10.1186/s12872-022-02461-8

    PMID: 35246021

    		 Sample: Plasma
  72. BMC Cardiovascular Disorders (2021) IF: 2.298
    MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1

    DOI: 10.1186/s12872-021-02228-7

    PMID: 34517822

    		 Sample: Vec
  73. JOURNAL OF MEDICAL VIROLOGY (2021) IF: 2.327
    Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19

    DOI: 10.1002/jmv.27294

    PMID: 34427934

    		 Sample: Serum
  74. PeerJ (2019) IF: 2.353
    The role of serum and urinary biomarkers in the diagnosis of early diabetic nephropathy in patients with type 2 diabetes

    DOI: 10.7717/peerj.7079
    Sample: Urinary,Serum
  75. Journal of Orthopaedic Surgery and Research (2022) IF: 2.359
    Circ_0043947 contributes to interleukin 1β-induced injury in chondrocytes by sponging miR-671-5p to up-regulate RTN3 expression in osteoarthritis pathology

    DOI: 10.1186/s13018-022-02970-4

    PMID: 35331286

    		 Sample: Chondrocytes
  76. CARDIOVASCULAR PATHOLOGY (2017) IF: 2.359
    C reactive protein and enzymatically modified LDL cooperatively promote dendritic cell-mediated T cell activation

    DOI: 10.1016/j.carpath.2017.03.009
    Sample: Cell Culture Supernatant
  77. CLINICAL RHEUMATOLOGY (2020) IF: 2.394
    The clinical value of interleukins-8, -10, and -17 in idiopathic granulomatous mastitis

    DOI: 10.1007/s10067-020-04925-8
    Sample: Blood
  78. MOLECULES (2015) IF: 2.416
    Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells

    DOI: 10.3390/molecules201219764
    Sample: Cell Lysate
  79. BIOLOGICAL TRACE ELEMENT RESEARCH (2019) IF: 2.431
    Study of Metal-Metal Interactions and Their Biomarkers Using an Intestinal Human Cell Line

    DOI: 10.1007/s12011-019-01831-2

    PMID: 31473895

    		 Sample: Cell Lysate
  80. COMPLEMENTARY THERAPIES IN MEDICINE (2022) IF: 2.446
    Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial

    DOI: 10.1016/j.ctim.2022.102819

    PMID: 35240291

    		 Sample: Serum
  81. Translational Pediatrics (2021) IF: 2.488
    Comparison of safety, effectiveness and serum inflammatory factor indexes of Saccharomyces boulardii versus Bifidobacterium triple viable in treating children with chronic diarrhea: a randomized trial

    DOI: 10.21037/tp-21-195
    Sample: Serum
  82. DIGESTIVE DISEASES (2020) IF: 2.493
    LncRNA PMS2L2 downregulates miR-24 through methylation to suppress cell apoptosis in ulcerative colitis

    DOI: 10.1159/000513330
    Sample: Hcnepcs
  83. PEDIATRIC PULMONOLOGY (2020) IF: 2.534
    Obstructive sleep apnea in children with hypothalamic obesity: Evaluation of possible related factors

    DOI: 10.1002/ppul.25097

    PMID: 32986303

    		 Sample: Plasma
  84. BIOSCIENCE REPORTS (2019) IF: 2.535
    Serum profile of cytokines and their genetic variants in metabolic syndrome and healthy subjects: a comparative study

    DOI: 10.1042/BSR20181202
    Sample: Serum
  85. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2020) IF: 2.575
    XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485

    DOI: 10.1080/13813455.2020.1789880

    PMID: 32669002

    		 Sample: Serum
  86. MICROBIAL PATHOGENESIS (2019) IF: 2.581
    Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles

    DOI: 10.1016/j.micpath.2019.103719

    PMID: 31493501

    		 Sample: Cell Culture Supernatant
  87. Canadian Journal of Infectious Diseases & Medical Microbiology (2022) IF: 2.585
    The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1 β Signaling Axis

    DOI: 10.1155/2022/5469236

    PMID: 35873363

    		 Sample: Ges-1 Cell
  88. Annals of Palliative Medicine (2021) IF: 2.595
    The effects of blood purification combined with antibiotics on extravascular lung water index, inflammatory factors, and prognosis of patients with severe acute pancreatitis complicated with acute respiratory distress syndrome.

    DOI: 10.21037/apm-21-2168
    Sample: Blood
  89. Annals of Palliative Medicine (2021) IF: 2.595
    Effect of probiotics supplementation combined with WeChat platform health management on nutritional status, inflammatory factors, and quality of life in patients with mild-to-moderate ulcerative colitis: a randomized trial.

    DOI: 10.21037/apm-21-1056
    Sample: Serum
  90. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019) IF: 2.606
    Intercalation of shRNA-plasmid in Mg–Al layered double hydroxide nanoparticles and its cellular internalization for possible treatment of neurodegenerative diseases

    DOI: 10.1016/j.jddst.2019.05.008
    Sample: Sh-Sy5Y Cells
  91. Dose-Response (2022) IF: 2.623
    Correlation of Ionized Magnesium with the Parameters of Oxidative Stress as Potential Biomarkers in Patients with Anxiety and Depression: A Pilot Study:

    DOI: 10.1177/15593258221116741
    Sample: Serum
  92. Evidence-based Complementary and Alternative Medicine (2021) IF: 2.63
    The Anti-Inflammatory Effect of Smilax china L. Extract on LPS-Stimulated THP-1 via Downregulation of MAPK and NF-κB Signaling Pathway

    DOI: 10.1155/2021/9958808
    Sample: Thp-1 Cells
  93. GENE (2019) IF: 2.638
    Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197

    DOI: 10.1016/j.gene.2019.05.012
    Sample: Human Umbilical Vein Endothelial Cells (Huvecs)
  94. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6.

    DOI: 10.1155/2022/9092311
    Sample: Human Nasal Epithelial Cell (Hnecs)
  95. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Efficacy of Ambroxol Hydrochloride Combined with Amoxicillin Potassium Clavulanate Combination on Children with Bronchopneumonia and Its Impact on the Level of Inflammatory Factors

    DOI: 10.1155/2022/2604114

    PMID: 36034961

    		 Sample: Serum
  96. ONCOLOGY REPORTS (2017) IF: 2.662
    PLD4 promotes M1 macrophages to perform antitumor effects in colon cancer cells

    DOI: 10.3892/or.2016.5216
    Sample: Macrophage
  97. Journal of Stroke & Cerebrovascular Diseases (2022) IF: 2.677
    Circ_0101874 overexpression strengthens PDE4D expression by targeting miR-335-5p to promote neuronal injury in ischemic stroke

    DOI: 10.1016/j.jstrokecerebrovasdis.2022.106817

    PMID: 36252429

    		 Sample: Sk-N-Sh Cells
  98. Applied Sciences-Basel (2021) IF: 2.679
    Biochemical Mapping of the Inflamed Human Dental Pulp

    DOI: 10.3390/app112110395
    Sample: Dental Pulp Lysates
  99. Applied Sciences-Basel (2022) IF: 2.679
    Assessment of Mineralization, Oxidative Stress, and Inflammation Mechanisms in the Pulp of Primary Teeth

    DOI: 10.3390/app12031554
    Sample: Dental Pulp Tissue
  100. Journal of Healthcare Engineering (2022) IF: 2.682
    Inhibition of microRNA-665 Alleviates Septic Acute Kidney Injury by Targeting Bcl-2

    DOI: 10.1155/2022/2961187

    PMID: 35281537

    		 Sample: Hk-2 Cell
  101. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019) IF: 2.705
    Long non-coding RNA MEG3 regulates CSE-induced apoptosis and inflammation via regulating miR-218 in 16HBE cells

    DOI: 10.1016/j.bbrc.2019.10.135

    PMID: 31668807

    		 Sample: Cell Culture Supernatant
  102. SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2020) IF: 2.717
    Early HIV infection is associated with reduced proportions of gamma delta T subsets as well as high creatinine and urea levels

    DOI: 10.1111/sji.12868

    PMID: 32052490

    		 Sample: Serum
  103. European Review for Medical and Pharmacological Sciences (2019) IF: 2.721
    Plasma concentration of ZCCHC14 contributes to prognostic efficacy in intracerebral hemorrhage patients.

    DOI: 10.26355/eurrev_201910_19167
    Sample: Plasma
  104. BURNS (2022) IF: 2.744
    A randomized controlled trial: Comparison of one-per-mil tumescent technique and tourniquet in surgery for burn hand contracture in creating clear operative field and assessment of functional outcome

    DOI: 10.1016/j.burns.2022.01.001

    PMID: 35016790

    		 Sample: Plasma
  105. BIOMEDICINE & PHARMACOTHERAPY (2017) IF: 2.759
    Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1–7) upregulation

    DOI: 10.1016/j.biopha.2017.11.151
    Sample: Cell Culture Supernatant,Serum
  106. PLoS One (2017) IF: 2.806
    High anti-human cytomegalovirus antibody levels are associated with the progression of essential hypertension and target organ damage in Han Chinese population

    DOI: 10.1371/journal.pone.0181440
    Sample: Serum
  107. BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2022) IF: 2.831
    Periodontal Ligament Stem Cells Reverse the High Glucose Level-Induced Inflammatory State of Macrophages

    DOI: 10.3967/bes2022.089

    PMID: 35945185

    		 Sample: Thp-1 Cell
  108. NEPHRON (2021) IF: 2.847
    XCL1 Aggravates Diabetic Nephropathy-Mediated Renal Glomerular Endothelial Cell Apoptosis and Inflammatory Response via Regulating p53/Nuclear Factor-Kappa B Pathway

    DOI: 10.1159/000518172

    PMID: 34518457

    		 Sample: Hrgecs
  109. Dermatologic Therapy (2021) IF: 2.851
    Carotid intima-media thickness and serum proinflammatory cytokine levels in rosacea patients without cardiovascular risk factors

    DOI: 10.1111/dth.14733

    PMID: 33389789

    		 Sample: Serum
  110. Odontology (2022) IF: 2.885
    Is adrenomedullin upregulation due to apical periodontitis independent of periodontal disease?

    DOI: 10.1007/s10266-022-00767-9
    Sample: Serum
  111. 3 Biotech (2022) IF: 2.893
    Nephroprotective effect of polyphenol-rich extract of Costus spicatus in cisplatin-induced nephrotoxicity in Wistar albino rats

    DOI: 10.1007/s13205-022-03233-z

    PMID: 35903285

    		 Sample: Kidney Tissue
  112. HUMAN & EXPERIMENTAL TOXICOLOGY (2022) IF: 2.903
    Fluorometholone inhibits high glucose-induced cellular senescence in human retinal endothelial cells:

    DOI: 10.1177/09603271221076107
    Sample: Human Retinal Endothelial Cell
  113. Molecular Medicine Reports (2021) IF: 2.952
    Transforming growth factor‑β1 functions as a competitive endogenous RNA that ameliorates intracranial hemorrhage injury by sponging microRNA‑93‑5p

    DOI: 10.3892/mmr.2021.12138

    PMID: 33955515

    		 Sample: Cell Culture Supernatant
  114. Gastroenterology Report (2020) IF: 2.96
    Effect of Helicobacter pylori-eradication therapy on hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomized–controlled pilot study

    DOI: 10.1093/gastro/goz058
    Sample: Serum
  115. PeerJ (2021) IF: 2.984
    Identification of key genes and crucial pathways for major depressive disorder using peripheral blood samples and chronic unpredictable mild stress rat models

    DOI: 10.7717/peerj.11694

    PMID: 34414022

    		 Sample: Plasma
  116. PeerJ (2022) IF: 2.984
    Human cytomegalovirus infection and its association with gestational diabetes mellitus during pregnancy

    DOI: 10.7717/peerj.12934

    PMID: 35186501

    		 Sample: Serum
  117. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020) IF: 2.985
    A novel human anti-TIGIT monoclonal antibody with excellent function in eliciting NK cell-mediated antitumor immunity

    DOI: 10.1016/j.bbrc.2020.12.013

    PMID: 33341068

    		 Sample: Cell Culture Supernatant
  118. NEUROTOXICITY RESEARCH (2020) IF: 2.992
    The Neuroimmune and Neurotoxic Fingerprint of Major Neurocognitive Psychosis or Deficit Schizophrenia: a Supervised Machine Learning Study

    DOI: 10.1007/s12640-019-00112-z
    Sample: Serum
  119. NEUROTOXICITY RESEARCH (2020) IF: 2.992
    Major Depression in Children with Transfusion-Dependent Thalassemia Is Strongly Associated with the Combined Effects of Blood Transfusion Rate, Iron Overload, and Increased Pro-inflammatory Cytokines

    DOI: 10.1007/s12640-020-00193-1

    PMID: 32335809

    		 Sample: Serum
  120. European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
    MiR-942-5p alleviates septic acute kidney injury by targeting FOXO3.

    DOI: 10.26355/eurrev_202006_21521
    Sample: Cell Culture Supernatant
  121. NEUROSCIENCE LETTERS (2022) IF: 3.046
    Role of CD36 rs1761667 AA genotype in the expression of inflammatory cytokines and Parkinson’s disease progression: A case-control study in a northern Han Chinese population

    DOI: 10.1016/j.neulet.2022.136736
    Sample: Plasma
  122. MOLECULES (2019) IF: 3.06
    Effect of Diosmin Administration in Patients with Chronic Venous Disorders on Selected Factors Affecting Angiogenesis

    DOI: 10.3390/molecules24183316
    Sample: Serum
  123. American Journal of Translational Research (2018) IF: 3.061
    LncRNA MALAT1 promotes relapse of breast cancer patients with postoperative fever

    PMID: 30416660

    		 Sample: Plasma
  124. INFLAMMATION RESEARCH (2019) IF: 3.061
    Common variants of genes encoding TLR4 and TLR4 pathway members TIRAP and IRAK1 are effective on MCP1, IL6, IL1β, and TNFα levels in type 2 diabetes and insulin resistance

    DOI: 10.1007/s00011-019-01263-7
    Sample: Serum
  125. MOLECULAR IMMUNOLOGY (2019) IF: 3.064
    IL-16 regulates macrophage polarization as a target gene of mir-145-3p

    DOI: 10.1016/j.molimm.2018.12.027

    PMID: 30634164

    		 Sample: Cell Lysate
  126. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021) IF: 3.105
    Circ_USP36 Silencing Attenuates Oxidized Low-Density Lipoprotein-Induced Dysfunction in Endothelial Cells in Atherosclerosis Through Mediating miR-197-3p/ROBO1 Axis

    DOI: 10.1097/FJC.0000000000001124

    PMID: 34369900

    		 Sample: Huvec Cells
  127. JOURNAL OF THE NEUROLOGICAL SCIENCES (2020) IF: 3.115
    Cytokine profile during pregnancy predicts relapses during pregnancy and postpartum in multiple sclerosis

    DOI: 10.1016/j.jns.2020.116811
    Sample: Serum
  128. INTERNATIONAL IMMUNOPHARMACOLOGY (2018) IF: 3.118
    S1P promotes inflammation-induced tube formation by HLECs via the S1PR1/NF-κB pathway

    DOI: 10.1016/j.intimp.2018.11.032

    PMID: 30476824

    		 Sample: Cell Culture Supernatant
  129. INTERNATIONAL IMMUNOPHARMACOLOGY (2018) IF: 3.118
    Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism

    DOI: 10.1016/j.intimp.2018.10.013
    Sample: Hepg2 Cells
  130. FISH & SHELLFISH IMMUNOLOGY (2018) IF: 3.185
    Molecular characterization and functional analysis of MyD88 from the tropical sea cucumber, Holothuria leucospilota

    DOI: 10.1016/j.fsi.2018.09.001
    Sample: Hek293T Cells
  131. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017) IF: 3.226
    The Pharmaceutical Device Prisma® Skin Promotes in Vitro Angiogenesis through Endothelial to Mesenchymal Transition during Skin Wound Healing

    DOI: 10.3390/ijms18081614
    Sample: Cell Culture Supernatant
  132. MEDIATORS OF INFLAMMATION (2017) IF: 3.232
    Short-Term Postoperative Cognitive Dysfunction and Inflammatory Response in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Pilot Study

    DOI: 10.1155/2017/3605350
    Sample: Serum
  133. LIFE SCIENCES (2018) IF: 3.234
    LncRNA PMS2L2 protects ATDC5 chondrocytes against lipopolysaccharide-induced inflammatory injury by sponging miR-203

    DOI: 10.1016/j.lfs.2018.12.020

    PMID: 30550887

    		 Sample: Cell Culture Supernatant
  134. DIABETES RESEARCH AND CLINICAL PRACTICE (2019) IF: 3.239
    Effect of Ramadan diurnal fasting on visceral adiposity and serum adipokines in overweight and obese individuals

    DOI: 10.1016/j.diabres.2019.05.023

    PMID: 31150725

    		 Sample: Serum
  135. PLoS One (2013) IF: 3.24
    Oxidative Burst of Circulating Neutrophils Following Traumatic Brain Injury in Human

    DOI: 10.1371/journal.pone.0068963
    Sample: Plasma
  136. PLoS One (2022) IF: 3.24
    Clinical characteristics and outcomes of COVID-19 patients in Bali, Indonesia

    DOI: 10.1371/journal.pone.0269026

    PMID: 35687545

    		 Sample: Serum
  137. Biomed Research International (2022) IF: 3.246
    Regulatory Effects of Fyn on Trophoblast Cell Behaviors and Function

    DOI: 10.1155/2022/6006981

    PMID: 36330453

    		 Sample: Htr-8/Svneo Cells,Jeg-3 Cells
  138. JOURNAL OF GENE MEDICINE (2020) IF: 3.258
    Human cytomegalovirus infection is correlated with atherosclerotic plaque vulnerability in carotid artery

    DOI: 10.1002/jgm.3236

    PMID: 32468600

    		 Sample: Serum
  139. Bioengineered (2022) IF: 3.269
    Nintedanib ameliorates oxidized low-density lipoprotein -induced inflammation and cellular senescence in vascular endothelial cells

    DOI: 10.1080/21655979.2022.2036913

    PMID: 35236245

    		 Sample: Huvecs
  140. Bioengineered (2021) IF: 3.269
    N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 3 or insulin like growth factor 2 mRNA binding protein 2 knockdown protects human bronchial epithelial cells from hypoxia/reoxygenation injury by inactivating p38 MAPK, AKT, ERK1/2, and

    DOI: 10.1080/21655979.2021.1999550
    Sample: Beas-2B Cell
  141. Bioengineered (2022) IF: 3.269
    Dihydroartemisinin targets fibroblast growth factor receptor 1 (FGFR1) to inhibit interleukin 17A (IL-17A)-induced hyperproliferation and inflammation of keratinocytes

    DOI: 10.1080/21655979.2021.2021701

    PMID: 35006038

    		 Sample: Hacat Cell
  142. Bioengineered (2022) IF: 3.269
    Circ_0001897 regulates high glucose-induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-29c-3p/transforming growth factor beta 2 axis

    DOI: 10.1080/21655979.2022.2070997

    PMID: 35510503

    		 Sample: Human Retinal Microvascular Endothelial Cell (Hrec
  143. Bioengineered (2021) IF: 3.269
    Carvedilol activates nuclear factor E2-related factor 2/ antioxidant response element pathway to inhibit oxidative stress and apoptosis of retinal pigment epithelial cells induced by high glucose

    DOI: 10.1080/21655979.2021.2012627

    PMID: 34898371

    		 Sample: Arpe-19 Cell
  144. CELLULAR IMMUNOLOGY (2019) IF: 3.291
    DosR antigen Rv1737c induces activation of macrophages dependent on the TLR2 pathway

    DOI: 10.1016/j.cellimm.2019.103947
    Sample: Thp-1 Cells
  145. MATERIALS TECHNOLOGY (2022) IF: 3.297
    Gold nanoparticles loaded TNF-α and CALNN peptide as a drug delivery system and promising therapeutic agent for breast cancer cells

    DOI: 10.1080/10667857.2022.2133073
    Sample: Mcf-7 Cell,Amj-13 Cell
  146. COMPLEMENTARY THERAPIES IN MEDICINE (2022) IF: 3.335
    Comparison of delta-tocotrienol and alpha-tocopherol effects on hepatic steatosis and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: A randomized double-blind active-controlled trial

    DOI: 10.1016/j.ctim.2022.102866

    PMID: 35933083

    		 Sample: Serum
  147. OncoTargets and Therapy (2020) IF: 3.337
    MiRNA505/NET1 Axis Acts as a CD8+ T-TIL Regulator in Non-Small Cell Lung Cancer

    DOI: 10.2147/OTT.S265859
    Sample: Cell Culture Supernatant
  148. TOXICOLOGY IN VITRO (2016) IF: 3.338
    Sublethal effects of zinc oxide nanoparticles on male reproductive cells

    DOI: 10.1016/j.tiv.2016.05.017
    Sample: Cell Culture Supernatant
  149. Clinical & Translational Oncology (2022) IF: 3.34
    Cancer cell-derived exosomal LINC00313 induces M2 macrophage differentiation in non-small cell lung cancer

    DOI: 10.1007/s12094-022-02907-7

    PMID: 35980503

    		 Sample: Thp-1 Cell,H1299 Cell
  150. Frontiers in Nutrition (2020) IF: 3.365
    A Novel 7-Days Prolonged Dietary Deprivation Regimen Improves ALT and UA After 3–6 Months Refeeding, Indicating Therapeutic Potential

    DOI: 10.3389/fnut.2020.00050
    Sample: Serum
  151. EXPERIMENTAL CELL RESEARCH (2020) IF: 3.383
    iTRAQ-based proteomics and in vitro experiments reveals essential roles of ACE and AP-N in the renin–angiotensin system-mediated congenital ureteropelvic junction obstruction

    DOI: 10.1016/j.yexcr.2020.112086
    Sample: Serum,Cell Sample
  152. International Journal of Environmental Research and Public Health (2021) IF: 3.39
    Assessment of Unstimulated Whole Salivary Tumor Necrosis Factor Alpha (TNF-α) and Cellular Micronuclei Levels in Snuff (Naswar) Users and Non-Users for Early Diagnosis of Oral Squamous Cell Carcinoma

    DOI: 10.3390/ijerph18147230

    PMID: 34299679

    		 Sample: Saliva
  153. MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2021) IF: 3.402
    Long non-coding RNA NEAT1 promotes lipopolysaccharide-induced injury in human tubule epithelial cells by regulating miR-93-5p/TXNIP axis

    DOI: 10.1007/s00430-021-00705-6

    PMID: 33885954

    		 Sample: Cell Culture Supernatant
  154. Journal of Medical Biochemistry (2022) IF: 3.402
    Cul4a attenuates LPS-induced acute kidney injury via blocking NF-kB signaling pathway in sepsis

    DOI: 10.5937/jomb0-33096
    Sample: Hk-2 Cell
  155. JOURNAL OF ETHNOPHARMACOLOGY (2019) IF: 3.414
    Notopterygium incisum extract (NRE) rescues cognitive deficits in APP/PS1 Alzhneimer's disease mice by attenuating amyloid-beta, tau, and neuroinflammation pathology

    DOI: 10.1016/j.jep.2019.112433

    PMID: 31783135

    		 Sample: Cell Culture Supernatant
  156. Frontiers in Pediatrics (2022) IF: 3.418
    Hyperoxia Induced Bronchopulmonary Dysplasia-Like Inflammation via miR34a-TNIP2-IL-1β Pathway

    DOI: 10.3389/fped.2022.805860
    Sample: Sputum
  157. JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448
    Eriodictyol inhibits survival and inflammatory responses and promotes apoptosis in rheumatoid arthritis fibroblast‐like synoviocytes through AKT/FOXO1 signaling

    DOI: 10.1002/jcb.28724
    Sample: Rheumatoid Arthritis (Ra) Fibroblast-Like Synovioc
  158. SHOCK (2021) IF: 3.454
    The Value of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) in Predicting the Severity and Prognosis of Patients After Cardiac Arrest: A Preliminary Observational Study

    DOI: 10.1097/SHK.0000000000001702

    PMID: 34276038

    		 Sample: Serum
  159. JOURNAL OF NEUROIMMUNOLOGY (2022) IF: 3.478
    Association between pro-inflammatory cytokines in cerebrospinal fluid and headache in patients with aneurysmal subarachnoid hemorrhage

    DOI: 10.1016/j.jneuroim.2022.577841

    PMID: 35279426

    		 Sample: Cerebrospinal Fluid (Csf)
  160. TOXICOLOGY IN VITRO (2021) IF: 3.5
    (3α)-3-(tiglinoyloxy)-ent-kaur-16-en-19-oic acid, isolated from Wedelia trilobata L., exerts an anti-inflammatory effect via the modulation of NF-κB, MAPK and mTOR pathway and autophagy in LPS-stimulated macrophages

    DOI: 10.1016/j.tiv.2021.105139

    PMID: 33705895

    		 Sample: Cell Culture Supernatant
  161. ACS Omega (2022) IF: 3.512
    Sarcococca saligna Hydroalcoholic Extract Ameliorates Arthritis in Complete Freund’s Adjuvant-Induced Arthritic Rats via Modulation of Inflammatory Biomarkers and Suppression of Oxidative Stress Markers

    DOI: 10.1021/acsomega.2c00619
    Sample: Serum
  162. JOURNAL OF PHARMACEUTICAL SCIENCES (2022) IF: 3.534
    Nanoparticles as a novel tool to inhibit inflammatory cytokines in human lymphocytes and macrophages of coronary artery disease

    DOI: 10.1016/j.xphs.2022.01.001

    PMID: 34999090

    		 Sample: Lymphocytes,Macrophages
  163. Nanoscale Research Letters (2020) IF: 3.578
    Nec-1 Attenuates Neurotoxicity Induced by Titanium Dioxide Nanomaterials on Sh-Sy5y Cells Through RIP1

    DOI: 10.1186/s11671-020-03300-5
    Sample: Sh-Sy5Y Cell
  164. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2022) IF: 3.657
    Early Diagnosis of Coronary Artery Disease by Inflammatory Biomarkers of Atherosclerosis in Patients with Angina

    DOI: 10.1089/jir.2022.0110

    PMID: 36121373

    		 Sample: Serum
  165. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2022) IF: 3.657
    Can the Prognosis of COVID-19 Disease Be Determined by Fecal Markers and Cytokines?

    DOI: 10.1089/jir.2022.0098

    PMID: 36179036

    		 Sample: Fecal
  166. APOPTOSIS (2015) IF: 3.685
    strain FP10

    DOI: 10.1007/s10495-015-1162-9
    Sample: Cell Culture Supernatant
  167. JOURNAL OF ETHNOPHARMACOLOGY (2020) IF: 3.69
    Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways

    DOI: 10.1016/j.jep.2020.113039

    PMID: 32497675

    		 Sample: Serum,Cell Culture Supernatant
  168. BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
    Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro

    DOI: 10.1016/j.biopha.2019.108706

    PMID: 30844656

    		 Sample: Wound Drainage Fluid
  169. SCHIZOPHRENIA RESEARCH (2020) IF: 3.759
    Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways

    DOI: 10.1016/j.schres.2020.05.003

    PMID: 32467068

    		 Sample: Serum
  170. Heliyon (2022) IF: 3.776
    Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles

    DOI: 10.1016/j.heliyon.2022.e11751
    Sample: A549 Cell
  171. Life-Basel (2021) IF: 3.817
    Establishing SW1353 Chondrocytes as a Cellular Model of Chondrolysis

    DOI: 10.3390/life11040272
    Sample: Sw1353 Cell
  172. INFLAMMOPHARMACOLOGY (2019) IF: 3.838
    Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein

    DOI: 10.1007/s10787-019-00628-y

    PMID: 31440860

    		 Sample: Serum
  173. JOURNAL OF AFFECTIVE DISORDERS (2020) IF: 3.892
    Construction of an exposure-pathway-phenotype in children with depression due to transfusion-dependent thalassemia: Results of (un)supervised machine learning.

    DOI: 10.1016/j.jad.2020.12.089
    Sample: Serum
  174. RESPIRATORY RESEARCH (2020) IF: 3.924
    Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

    DOI: 10.1186/s12931-020-01587-7
    Sample: Thp-1 Cell
  175. Annals of Translational Medicine (2021) IF: 3.932
    Combination of oncolytic adenovirus ZD55 harboring TRAIL-IETD-MnSOD and cytokine-induced killer cells against lung cancer

    DOI: 10.21037/atm-21-4479

    PMID: 34790733

    		 Sample: Serum,Beas-2B Cell
  176. Annals of Translational Medicine (2021) IF: 3.932
    A simple lectin-based biochip might display the potential clinical value of glycomics in patients with spontaneous intracerebral hemorrhage

    DOI: 10.21037/atm-20-7315

    PMID: 33987242

    		 Sample: Serum
  177. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice

    DOI: 10.1016/j.intimp.2020.106987

    PMID: 33217691

    		 Sample: Cell Culture Supernatant
  178. NEUROGASTROENTEROLOGY AND MOTILITY (2022) IF: 3.96
    Somatization is associated with altered serum levels of vitamin D, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome

    DOI: 10.1111/nmo.14512
    Sample: Serum
  179. APOPTOSIS (2018) IF: 3.967
    MiRNA-126 expression inhibits IL-23R mediated TNF-α or IFN-γ production in fibroblast-like synoviocytes in a mice model of collagen-induced rheumatoid arthritis

    DOI: 10.1007/s10495-018-1474-7
    Sample: Serum
  180. CELLULAR SIGNALLING (2020) IF: 3.968
    HDAC1 promotes artery injury through activation of VAV3 by binding to miR-182-5p in atherosclerotic mice model

    DOI: 10.1016/j.cellsig.2020.109840

    PMID: 33221374

    		 Sample: Cell Culture Supernatant
  181. NEUROCHEMICAL RESEARCH (2021) IF: 3.996
    Silencing of UCA1 Protects Against MPP+-Induced Cytotoxicity in SK-N-SH Cells via Modulating KCTD20 Expression by Sponging miR-423-5p

    DOI: 10.1007/s11064-020-03214-9
    Sample: Cell Culture Supernatant
  182. Scientific Reports (2020) IF: 3.998
    Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits

    DOI: 10.1038/s41598-020-68543-9

    PMID: 32669704

    		 Sample: Cell Culture Supernatant
  183. Pediatric Obesity (2021) IF: 4
    The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial

    DOI: 10.1111/ijpo.12872

    PMID: 34881510

    		 Sample: Serum
  184. Frontiers in Neurology (2022) IF: 4.003
    The Effects of Enriched Rehabilitation on Cognitive Function and Serum Glutamate Levels Post-stroke

    DOI: 10.3389/fneur.2022.829090

    PMID: 35370905

    		 Sample: Serum
  185. JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2020) IF: 4.018
    Inhibition of TLR2/TLR4 alleviates the Neisseria gonorrhoeae infection damage in human endometrial epithelial cells via Nrf2 and NF-Kβsignaling

    DOI: 10.1016/j.jri.2020.103192

    PMID: 32950783

    		 Sample: Cell Culture Supernatant
  186. INFLAMMATION (2022) IF: 4.092
    LncRNA FLG-AS1 Mitigates Diabetic Retinopathy by Regulating Retinal Epithelial Cell Inflammation, Oxidative Stress, and Apoptosis via miR-380-3p/SOCS6 Axis

    DOI: 10.1007/s10753-022-01665-6

    PMID: 35461393

    		 Sample: Arpe-19 Cell
  187. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021) IF: 4.101
    A functional polymorphism at the miR‑491‑5p binding site in the 3'‑untranslated region of the MMP‑9 gene increases the risk of developing ventilator‑associated pneumonia

    DOI: 10.3892/ijmm.2021.5050

    PMID: 34664683

    		 Sample: Peripheral Blood
  188. ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
    LncRNA MEG3 ameliorates NiO nanoparticles-induced pulmonary inflammatory damage via suppressing the p38 mitogen activated protein kinases pathway

    DOI: 10.1002/tox.23464

    PMID: 35006638

    		 Sample: A549 Cell
  189. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021) IF: 4.223
    Occupational exposure of rural workers to pesticides in a vegetable-producing region in Brazil

    DOI: 10.1007/s11356-021-12444-5

    PMID: 33469792

    		 Sample: Plasma
  190. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021) IF: 4.223
    Biochemical investigation of human exposure to aflatoxin M1 and its association with risk factors of diabetes mellitus

    DOI: 10.1007/s11356-021-14871-w

    PMID: 34216342

    		 Sample: Serum
  191. Frontiers in Pharmacology (2020) IF: 4.225
    NRF2 -617 C/A Polymorphism Impacts Proinflammatory Cytokine Levels, Survival, and Transplant-Related Mortality After Hematopoietic Stem Cell Transplantation in Adult Patients Receiving Busulfan-Based Conditioning Regimens

    DOI: 10.3389/fphar.2020.563321

    PMID: 33384597

    		 Sample: Plasma
  192. International Journal of Nanomedicine (2017) IF: 4.3
    Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo

    DOI: 10.2147/IJN.S134897
    Sample: Cell Culture Supernatant,Serum
  193. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019) IF: 4.328
    Inflammation-dependent ISG15 upregulation mediates MIA-induced dendrite damages and depression by disrupting NEDD4/Rap2A signaling

    DOI: 10.1016/j.bbadis.2019.02.020

    PMID: 30826466

    		 Sample: Serum
  194. Epigenomics (2023) IF: 4.357
    Low-dose 5-aza-2′-deoxycytidine protects against early renal injury by increasing klotho expression

    DOI: 10.2217/epi-2022-0430
    Sample: Serum,Hk-2 Cell
  195. DRUG DEVELOPMENT RESEARCH (2021) IF: 4.36
    CircTHBS1 facilitates the progression of interstitial cystitis depending on the regulation of miR-139-5p/MFN2 axis

    DOI: 10.1002/ddr.21864

    PMID: 34368980

    		 Sample: Serum
  196. Journal of Atherosclerosis and Thrombosis (2022) IF: 4.394
    Oxygenized Low-Density Lipoprotein-Induced ASMC Dysregulation Depends on circ_0000345-Mediated Regulatory Mechanism

    DOI: 10.5551/jat.63327

    PMID: 36171087

    		 Sample: Asmcs
  197. PLoS Neglected Tropical Diseases (2021) IF: 4.411
    Anaphylatoxins orchestrate Th17 response via interactions between CD16+ monocytes and pleural mesothelial cells in tuberculous pleural effusion

    DOI: 10.1371/journal.pntd.0009508

    PMID: 34237073

    		 Sample: Pleural Fluid
  198. JOURNAL OF PERIODONTAL RESEARCH (2022) IF: 4.419
    Gingival crevicular fluid lipocalin-2 and semaphorin3A in stage III periodontitis: Non-surgical periodontal treatment effects

    DOI: 10.1111/jre.12995

    PMID: 35468224

    		 Sample: Gingival Crevicular Fluid (Gcf)
  199. EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 4.432
    Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs

    DOI: 10.1016/j.ejphar.2019.172797
    Sample: Huvecs Cells
  200. Cancer Biology & Medicine (2019) IF: 4.467
    TNFα inhibitor C87 sensitizes EGFRvIII transfected glioblastoma cells to gefitinib by a concurrent blockade of TNFα signaling

    DOI: 10.20892/j.issn.2095-3941.2019.0011
    Sample: Cell Sample
  201. INFLAMMOPHARMACOLOGY (2022) IF: 4.473
    Sarcococca saligna extract attenuates formaldehyde-induced arthritis in Wistar rats via modulation of pro-inflammatory and inflammatory biomarkers

    DOI: 10.1007/s10787-022-00929-9

    PMID: 35218463

    		 Sample: Blood
  202. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis

    DOI: 10.1016/j.biopha.2020.110326
    Sample: Cell Culture Supernatant
  203. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    LncRNA SNHG5 regulates cell apoptosis and inflammation by miR-132/PTEN axis in COPD

    DOI: 10.1016/j.biopha.2020.110016

    PMID: 32145584

    		 Sample: Cell Culture Supernatant
  204. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020) IF: 4.556
    Short-Term Physiological Effects of a Very Low-Calorie Ketogenic Diet: Effects on Adiponectin Levels and Inflammatory States

    DOI: 10.3390/ijms21093228
    Sample: Serum
  205. FISH & SHELLFISH IMMUNOLOGY (2020) IF: 4.581
    Molecular characterization, inducible expression and functional analysis of an IKKβ from the tropical sea cucumber Holothuria leucospilota

    DOI: 10.1016/j.fsi.2020.06.024

    PMID: 32585358

    		 Sample: Cell Culture Supernatant
  206. Oxidative Medicine and Cellular Longevity (2017) IF: 4.593
    ROS-Dependent Activation of Autophagy through the PI3K/Akt/mTOR Pathway Is Induced by Hydroxysafflor Yellow A-Sonodynamic Therapy in THP-1 Macrophages

    DOI: 10.1155/2017/8519169
    Sample: Cell Culture Supernatant
  207. International Journal of Environmental Research and Public Health (2022) IF: 4.614
    Effects of Microencapsulated Ferulic Acid or Its Prodrug Methyl Ferulate on Neuroinflammation Induced by Muramyl Dipeptide

    DOI: 10.3390/ijerph191710609

    PMID: 36078325

    		 Sample: Pc12 Cell
  208. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021) IF: 4.799
    The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis

    DOI: 10.1167/iovs.62.9.12

    PMID: 34236384

    		 Sample: Hcecs Cells
  209. Journal of Immunology Research (2021) IF: 4.818
    Remote Inflammatory Preconditioning Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Inhibition of Intrinsic Apoptosis in Rats

    DOI: 10.1155/2021/1125199

    PMID: 34595242

    		 Sample: Serum
  210. BIOCONJUGATE CHEMISTRY (2017) IF: 4.818
    Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages and Promote Beneficial Antiatherosclerotic Mechanisms

    DOI: 10.1021/acs.bioconjchem.6b00600
    Sample: Cell Culture Supernatant
  211. Aging-US (2020) IF: 4.831
    In situ self-assembly of Au-antimiR-155 nanocomplexes mediates TLR3-dependent apoptosis in hepatocellular carcinoma cells.

    DOI: 10.18632/aging.103799
    Sample: Cell Culture Medium
  212. JOURNAL OF IMMUNOLOGY (2020) IF: 4.886
    CALML6 Controls TAK1 Ubiquitination and Confers Protection against Acute Inflammation

    DOI: 10.4049/jimmunol.1901042

    PMID: 32303555

    		 Sample: Cell Culture Supernatant
  213. INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 4.932
    Arsenic trioxide improves Treg and Th17 balance by modulating STAT3 in treatment-naïve rheumatoid arthritis patients

    DOI: 10.1016/j.intimp.2019.05.001
    Sample: Pbmcs Cells
  214. JOURNAL OF LEUKOCYTE BIOLOGY (2022) IF: 4.962
    Periodontal ligament stem cells promote polarization of M2 macrophages

    DOI: 10.1002/JLB.1MA1220-853RR

    PMID: 34982483

    		 Sample: Thp-1 Cell
  215. JOURNAL OF LEUKOCYTE BIOLOGY (2021) IF: 4.962
    Leptin correlates with monocytes activation and severe condition in COVID-19 patients

    DOI: 10.1002/JLB.5HI1020-704R

    PMID: 33404078

    		 Sample: Serum
  216. PPAR Research (2021) IF: 4.964
    PPAR-Alpha Agonist Fenofibrate Combined with Octreotide Acetate in the Treatment of Acute Hyperlipidemia Pancreatitis

    DOI: 10.1155/2021/6629455

    PMID: 33968146

    		 Sample: Serum
  217. Scientific Reports (2022) IF: 4.996
    Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis

    DOI: 10.1038/s41598-022-21816-x
    Sample: Serum
  218. CELL PROLIFERATION (2019) IF: 5.039
    Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function

    DOI: 10.1111/cpr.12673
    Sample: Caco2 Cells，Ht‐29 Cell
  219. Journal of Functional Foods (2022) IF: 5.223
    High fiber multigrain supplementation improved disease activity score, circulating inflammatory and oxidative stress biomarkers in rheumatoid arthritis (RA) patients: A randomized human clinical trial

    DOI: 10.1016/j.jff.2022.105392
    Sample: Blood
  220. CLINICAL SCIENCE (2020) IF: 5.223
    Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function

    DOI: 10.1042/CS20200047

    PMID: 32219341

    		 Sample: Cell Culture Supernatant
  221. Biomaterials Science (2019) IF: 5.251
    Silk fibroin-alginate based beads for human mesenchymal stem cell differentiation in 3D

    DOI: 10.1039/C9BM01000A
    Sample: Thp-1 Cells
  222. Frontiers in Cellular and Infection Microbiology (2016) IF: 5.293
    Positive Feedback Cycle of TNFα Promotes Staphylococcal Enterotoxin B-Induced THP-1 Cell Apoptosis

    DOI: 10.3389/fcimb.2016.00109
    Sample: Cell Culture Supernatant
  223. Frontiers in Cellular and Infection Microbiology (2021) IF: 5.293
    GLUT3 as an Intersection of Glycerophospholipid Metabolism and the Innate Immune Response to Candida albicans

    DOI: 10.3389/fcimb.2021.648988
    Sample: Thp-1 Cells
  224. MOLECULAR NUTRITION & FOOD RESEARCH (2020) IF: 5.309
    Quercetin‐3‐O‐Glucuronide Alleviates Cognitive Deficit and Toxicity in Aβ1‐42‐Induced AD‐Like Mice and SH‐SY5Y Cells

    DOI: 10.1002/mnfr.202000660
    Sample: Cell Culture Supernatant
  225. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
    Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fission

    DOI: 10.1111/jcmm.17062

    PMID: 34786826

    		 Sample: Serum
  226. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
    Downregulation of p300/CBP-associated factor inhibits cardiomyocyte apoptosis via suppression of NF-κB pathway in ischaemia/reperfusion injury rats

    DOI: 10.1111/jcmm.16959

    PMID: 34601814

    		 Sample: Myocardial Tissue,Blood
  227. Food & Function (2022) IF: 5.396
    A randomised, double-blind, placebo-controlled trial of Bifidobacterium bifidum CCFM16 for manipulation of gut microbiota and relief from chronic constipation

    DOI: 10.1039/D1FO03896F
    Sample: Serum
  228. JOURNAL OF IMMUNOLOGY (2022) IF: 5.422
    Fungal Patterns Induce Cytokine Expression through Fluxes of Metabolic Intermediates That Support Glycolysis and Oxidative Phosphorylation

    DOI: 10.4049/jimmunol.2100666

    PMID: 35688467

    		 Sample: Human Monocyte-Derived Dendritic Cells (Dcs)
  229. OSTEOARTHRITIS AND CARTILAGE (2018) IF: 5.454
    Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis

    DOI: 10.1016/j.joca.2018.05.003
    Sample: Serum
  230. JOURNAL OF CELLULAR PHYSIOLOGY (2020) IF: 5.546
    Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post-coculture with activated neutrophils

    DOI: 10.1002/jcp.29713

    PMID: 32385929

    		 Sample: Cell Culture Supernatant
  231. Scientific Reports (2015) IF: 5.578
    The role of miR-19b in the inhibition of endothelial cell apoptosis and its relationship with coronary artery disease

    DOI: 10.1038/srep15132
    Sample: Serum
  232. Molecular Therapy-Nucleic Acids (2018) IF: 5.66
    miR-93-5p-Containing Exosomes Treatment Attenuates Acute Myocardial Infarction-Induced Myocardial Damage

    DOI: 10.1016/j.omtn.2018.01.010
    Sample: Serum
  233. Aging-US (2022) IF: 5.682
    The TLR4/NF-κB/MAGI-2 signaling pathway mediates postoperative delirium

    DOI: 10.18632/aging.203955
    Sample: Plasma,Cerebrospinal Fluid
  234. MOLECULAR NEUROBIOLOGY (2022) IF: 5.682
    Acrylamide Induces Neurotoxicity in SH-SY5Y Cells via NLRP3-mediated Pyroptosis

    DOI: 10.1007/s12035-022-03098-6
  235. Cell Communication and Signaling (2022) IF: 5.712
    The ROCK-ezrin signaling pathway mediates LPS-induced cytokine production in pulmonary alveolar epithelial cells

    DOI: 10.1186/s12964-022-00879-3

    PMID: 35551614

    		 Sample: A549 Cell
  236. INTERNATIONAL IMMUNOPHARMACOLOGY (2023) IF: 5.714
    Escin alleviates stress-induced intestinal dysfunction to protect brain injury by regulating the gut-brain axis in ischemic stroke rats

    DOI: 10.1016/j.intimp.2022.109659
    Sample: Caco-2 Cell
  237. INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 5.714
    CircVAPA contributes to hyper-proliferation and inflammation of keratinocytes through miR-125b-5p/sirt6 axis in psoriasis

    DOI: 10.1016/j.intimp.2022.109632
    Sample: Hacat Cells
  238. WORLD JOURNAL OF GASTROENTEROLOGY (2021) IF: 5.742
    Serum soluble suppression of tumorigenicity 2 as a novel inflammatory marker predicts the severity of acute pancreatitis

    DOI: 10.3748/wjg.v27.i38.6489

    PMID: 34720537

    		 Sample: Serum
  239. WORLD JOURNAL OF GASTROENTEROLOGY (2016) IF: 5.742
    Inhibitory effect of miR-125b on hepatitis C virus core protein-induced TLR2/MyD88 signaling in THP-1 cells

    DOI: 10.3748/wjg.v22.i17.4354
    Sample: Cell Culture Supernatant
  240. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291
    miR-122–5p regulates hepatocytes damage caused by BaP and DBP co-exposure through SOCS1/STAT3 signaling in vitro

    DOI: 10.1016/j.ecoenv.2021.112570
    Sample: L02 Cell
  241. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022) IF: 6.291
    GSDMD-miR-223-NLRP3 axis involved in B(a)P-induced inflammatory injury of alveolar epithelial cells

    DOI: 10.1016/j.ecoenv.2022.113286

    PMID: 35144130

    		 Sample: A549 Cell
  242. Antioxidants (2021) IF: 6.313
    Correlations between Salivary Immuno-Biochemical Markers and HbA1c in Type 2 Diabetes Subjects before and after Dental Extraction

    DOI: 10.3390/antiox10111741

    PMID: 34829612

    		 Sample: Saliva
  243. Food & Function (2022) IF: 6.317
    Whole grain germinated brown rice regulates intestinal immune homeostasis and gastrointestinal hormones in type 2 diabetic patients—a randomized control trial

    DOI: 10.1039/D2FO00477A
    Sample: Serum
  244. ENVIRONMENTAL RESEARCH (2021) IF: 6.498
    Changes in genotoxicity, inflammatory and oxidative stress parameters of workers in marble processing plants

    DOI: 10.1016/j.envres.2021.111209

    PMID: 33895109

    		 Sample: Plasma
  245. Pharmaceutics (2022) IF: 6.525
    In Vitro Antibacterial and Anti-Inflammatory Activity of Arctostaphylos uva-ursi Leaf Extract against Cutibacterium acnes

    DOI: 10.3390/pharmaceutics14091952

    PMID: 36145700

    		 Sample: Hacat Cell
  246. BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
    Compound Danshen Dripping Pill inhibits doxorubicin or isoproterenol-induced cardiotoxicity

    DOI: 10.1016/j.biopha.2021.111531

    PMID: 34311530

    		 Sample: Serum
  247. Oxidative Medicine and Cellular Longevity (2021) IF: 6.543
    Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

    DOI: 10.1155/2021/5584447

    PMID: 34239691

    		 Sample: Np Cells
  248. ANALYTICA CHIMICA ACTA (2021) IF: 6.558
    Simple and facile carbon dots based electrochemical biosensor for TNF-α targeting in cancer patient's sample

    DOI: 10.1016/j.aca.2021.338909

    PMID: 34602194

    		 Sample: Serum
  249. Frontiers in Nutrition (2022) IF: 6.59
    Different oral and gut microbial profiles in those with Alzheimer's disease consuming anti-inflammatory diets.

    DOI: 10.3389/fnut.2022.974694
    Sample: Serum
  250. Nutrients (2022) IF: 6.706
    Thymoquinone Effect on Monocyte-Derived Macrophages, Cell-Surface Molecule Expression, and Phagocytosis

    DOI: 10.3390/nu14245240
    Sample: Macrophage
  251. Nutrients (2023) IF: 6.706
    Safety and Effects of Lactobacillus paracasei TISTR 2593 Supplementation on Improving Cholesterol Metabolism and Atherosclerosis-Related Parameters in Subjects with Hypercholesterolemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    DOI: 10.3390/nu15030661
    Sample: Serum
  252. Nutrients (2022) IF: 6.706
    Relationship between the Dietary Inflammatory Index Score and Cytokine Levels in Chinese Pregnant Women during the Second and Third Trimesters

    DOI: 10.3390/nu15010194
    Sample: Serum
  253. Nutrients (2022) IF: 6.706
    Alteration in Gut Microbiota Associated with Zinc Deficiency in School-Age Children

    DOI: 10.3390/nu14142895

    PMID: 35889856

    		 Sample: Serum
  254. ELECTROCHIMICA ACTA (2021) IF: 6.901
    MoS2 nanoflower based electrochemical biosensor for TNF alpha detection in cancer patients

    DOI: 10.1016/j.electacta.2021.139736
    Sample: Serum
  255. Journal of Inflammation Research (2021) IF: 6.922
    Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells

    DOI: 10.2147/JIR.S317182
    Sample: U937 Cell
  256. JOURNAL OF PERIODONTOLOGY (2021) IF: 6.993
    Evaluation of galectin-3, peptidylarginine deiminase-4 and tumor necrosis factor-α levels in gingival crevicular fluid for periodontal health, gingivitis and stage III grade C periodontitis: A pilot study

    DOI: 10.1002/JPER.21-0137

    PMID: 33913157

    		 Sample: Gingival Crevicular Fluid
  257. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2023) IF: 7.129
    Acute liver injury induced by carbon tetrachloride reversal by Gandankang aqueous extracts through nuclear factor erythroid 2-related factor 2 signaling pathway

    DOI: 10.1016/j.ecoenv.2023.114527
    Sample: Hepg2 Cell
  258. JOURNAL OF INVESTIGATIVE DERMATOLOGY (2020) IF: 7.143
    MicroRNA-101-3p Downregulates TLR2 Expression, Leading to Reduction in Cytokine Production by Treponema pallidum–Stimulated Macrophages

    DOI: 10.1016/j.jid.2019.12.012
    Sample: Plasma,Thp-1 Cell
  259. BRAIN BEHAVIOR AND IMMUNITY (2021) IF: 7.217
    Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial

    DOI: 10.1016/j.bbi.2021.11.023

    PMID: 34875345

    		 Sample: Serum
  260. Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
    Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury

    DOI: 10.1155/2022/3576892

    PMID: 35855864

    		 Sample: Serum
  261. Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
    Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial.

    DOI: 10.1155/2022/4631983
    Sample: Plasma
  262. Journal of Intensive Care (2023) IF: 7.52
    Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study

    DOI: 10.1186/s40560-023-00653-8
    Sample: Serum
  263. Frontiers in Immunology (2022) IF: 7.561
    TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage-Related Neutrophilic Inflammation in Asthma.

    DOI: 10.3389/fimmu.2022.883885
    Sample: Thp-1 Monocytes
  264. Frontiers in Immunology (2021) IF: 7.561
    Lactobacillus plantarum CCFM1143 Alleviates Chronic Diarrhea via Inflammation Regulation and Gut Microbiota Modulation: A Double-Blind, Randomized, Placebo-Controlled Study

    DOI: 10.3389/fimmu.2021.746585

    PMID: 34721416

    		 Sample: Serum
  265. Antioxidants (2022) IF: 7.675
    Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis

    DOI: 10.3390/antiox11112172
  266. Antioxidants (2022) IF: 7.675
    Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia

    DOI: 10.3390/antiox12010074
    Sample: Hmc3 Cells
  267. OncoImmunology (2017) IF: 7.719
    Exploiting a new strategy to induce immunogenic cell death to improve dendritic cell-based vaccines for lymphoma immunotherapy

    DOI: 10.1080/2162402X.2017.1356964
    Sample: Cell Culture Supernatant
  268. Nanoscale (2021) IF: 7.79
    Rational design of a prodrug to inhibit self-inflammation for cancer treatment

    DOI: 10.1039/D1NR00132A

    PMID: 33710220

    		 Sample: Serum,Cell Culture Supernatant(Dendritic Cells,4T1
  269. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
    Physicochemical properties and protective effects on UVA-induced photoaging in Hs68 cells of Pleurotus ostreatus polysaccharides by fractional precipitation

    DOI: 10.1016/j.ijbiomac.2022.12.254
    Sample: Hs68 Cell
  270. ACS Applied Materials & Interfaces (2019) IF: 8.456
    Red Blood Cells-Derived Vesicles for Delivery of Lipophilic Drug Camptothecin

    DOI: 10.1021/acsami.9b04827
    Sample: Thp-1 Cells
  271. Cell Death & Disease (2021) IF: 8.469
    Circular RNA circACSL1 aggravated myocardial inflammation and myocardial injury by sponging miR-8055 and regulating MAPK14 expression

    DOI: 10.1038/s41419-021-03777-7

    PMID: 33986259

    		 Sample: Cell Culture Supernatant
  272. CANCER LETTERS (2022) IF: 8.679
    Decreased CXCR2 expression on circulating monocytes of colorectal cancer impairs recruitment and induces Re-education of tumor-associated macrophages

    DOI: 10.1016/j.canlet.2022.01.004

    PMID: 34999169

    		 Sample: Serum,Thp-1 Cell,Human Circulating Cd14+ Monocytes
  273. EXPERIMENTAL AND MOLECULAR MEDICINE (2022) IF: 8.718
    CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia–reperfusion injury

    DOI: 10.1038/s12276-021-00720-w
    Sample: Cardiac Microvascular Endothelial Cell (Cmecs),Car
  274. Molecular Therapy-Nucleic Acids (2021) IF: 8.886
    Interfering microRNA-410 attenuates atherosclerosis via the HDAC1/KLF5/IKBα/NF-κB axis

    DOI: 10.1016/j.omtn.2021.03.009

    PMID: 33981482

    		 Sample: Plasma
  275. Molecular Therapy-Nucleic Acids (2021) IF: 8.886
    Enhancer RNA lnc-CES1-1 inhibits decidual cell migration by interacting with RNA-binding protein FUS and activating PPARγ in URPL

    DOI: 10.1016/j.omtn.2021.02.018

    PMID: 33738142

    		 Sample: Cell Culture Supernatant(Htr-8/Svneo Cells,Jeg-3 C
  276. Journal of Neuroinflammation (2022) IF: 9.587
    Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell death of neurons in vitro

    DOI: 10.1186/s12974-022-02535-6

    PMID: 35768823

    		 Sample: Cerebrospinal Fluid (Csf),Peripheral Monocytes
  277. ENVIRONMENTAL POLLUTION (2022) IF: 9.988
    Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line

    DOI: 10.1016/j.envpol.2022.120217

    PMID: 36155221

    		 Sample: Hmc3 Cell
  278. Journal of Crohns & Colitis (2022) IF: 10.02
    Association of neutrophil extracellular traps with fistula healing in patients with complex perianal fistulising Crohn’s disease

    DOI: 10.1093/ecco-jcc/jjac171
    Sample: Perianal Fistula
  279. JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
    Biodegradable MoSe2-polyvinylpyrrolidone nanoparticles with multi-enzyme activity for ameliorating acute pancreatitis

    DOI: 10.1186/s12951-022-01288-x

    PMID: 35248068

    		 Sample: Serum
  280. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020) IF: 11.161
    MiRNA-340-5p mediates the functional and infiltrative promotion of tumor-infiltrating CD8 + T lymphocytes in human diffuse large B cell lymphoma

    DOI: 10.1186/s13046-020-01752-2

    PMID: 33168024

    		 Sample: Cell Culture Supernatant
  281. Theranostics (2021) IF: 11.556
    A SCID mouse-human lung xenograft model of SARS-CoV-2 infection

    DOI: 10.7150/thno.58321

    PMID: 33995679

    		 Sample: Tissue Homogenate
  282. ACS Nano (2017) IF: 13.942
    Overcoming the Heat Endurance of Tumor Cells by Interfering with the Anaerobic Glycolysis Metabolism for Improved Photothermal Therapy

    DOI: 10.1021/acsnano.6b06658
    Sample: Cell Culture Supernatant
  283. HEPATOLOGY (2020) IF: 17.425
    Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD

    DOI: 10.1002/hep.31056

    PMID: 31808577

    		 Sample: Serum
  284. CELL (2020) IF: 38.637
    Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output

    DOI: 10.1016/j.cell.2020.08.009

    PMID: 33015716

    		 Sample: Cell Culture Medium
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Reviews/Q&A

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Verified Customer

P******* Submitted [ Jan 17 2023 ]

  • Species:Human
  • Description:Can I get this kit in Nigeria?
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Q

a***lSubmitted [ Jul 17 2024 ]

Asked: Do the protocol needs high speed centrifugation? What is the rpm to spin?

Reply

A

adminSubmitted [ Jul 17 2024 ]

Answered: Lyophilized Standard requires high-speed centrifugation, Centrifuge the standard at 10,000×g for 1 min.

Q

a***lSubmitted [ Jul 17 2024 ]

Asked: Do the protocol needs high speed centrifugation? What is the rpm to spin?

Reply

A

adminSubmitted [ Jul 17 2024 ]

Answered: Lyophilized Standard requires high-speed centrifugation, Centrifuge the standard at 10,000×g for 1 min.

Q

Z******rSubmitted [ Jun 30 2024 ]

Asked: For how many subjects is one kit enough?

Reply

A

adminSubmitted [ Jun 30 2024 ]

Answered: Hello Zvonimir, Thanks for your question. I will send email to you about the answer details. Please check your email later. Have a nice day! Best regards, Sophie International Sales Manager Email: sophie@elabscience.com www.linkedin.com/in/elabscience Elabscience Bionovation Inc. www.elabscience.com US Tel: 240-252-7368 China Tel: 86-27-87385095 Fax: +1 832 243 6017 Mobile: +86 136 5989 1476 (WhatsApp, Wechat, Skype) l 14780 Memorial Drive, Suite 105, Houston, Texas 77079

Q

S***aSubmitted [ Feb 14 2023 ]

Asked: \"For the kit E-EL-H0109, we have validated healthy human serum samples with the kit, the reference values of healthy human serum samples are below 30 pg/mL with individual differences.\" Is there any references that I can look up to?

Reply

A

adminSubmitted [ Feb 14 2023 ]

Answered: Hi，Sofia. I have replied you by email. Pls check the attachment of your mailbox.

Q

A***********nSubmitted [ Aug 08 2022 ]

Asked: Is there a reference range for normal individuals for this KIT?

Reply

A

adminSubmitted [ Aug 08 2022 ]

Answered: For the kit E-EL-H0109, we have validated healthy human serum samples with the kit, the reference values of healthy human serum samples are below 30 pg/mL with individual differences.

Q

S*********nSubmitted [ Aug 05 2021 ]

Asked: My kit got expired in April 2020. Shall we perform the experiment with the kit?

Reply

A

adminSubmitted [ Aug 05 2021 ]

Answered: Thanks for your message. The expired kit can be used to perform experiment anymore. By the way, where did you ordered the kit from?

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