Current Position:Home>>Antibodies>>Pathological Antibodies>> MLH1 Monoclonal Antibody
Catalog number:PA6124
Synonyms:MLH1
Reactivity: Human
Applications: IHC-P
Lead Time:Order now, ship in 3 daysWelcome to order from local distributors.
Add to cart Compare Bulk request ManualSize | 3mL/6mL(Ready-to-Use) 100μL/200μL(Concentrated) |
Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
Source | Mouse |
Reactivity | Human |
Application | IHC-P |
Background | MutL Protein Homolog 1(MLH1) is a mismatch repair gene, which is located on p-arm 21.3 of chromosome 3. And DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite reproducibility is caused by the slippage of the hinge misalignment during DNA replication, also known as microsatellite instability. The defects of these DNA repair pathways are related to some human tumors. The mutant mismatch repair gene is often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant genetic diseases. |