MSH2 Monoclonal Antibody

Name: MSH2 Monoclonal Antibody
Brand: Elabscience
SKU: PA6750
Price: 282 USD
Availability: InStock

Catalog number:PA6750

Synonyms:MSH2

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Price: $282

Reactivity: Human

Applications: IHC-P

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Size	3mL/6mL(Ready-to-Use) 100μL/200μL(Concentrated)
Storage	The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months.
Source	Mouse
Reactivity	Human
Application	IHC-P
Background	DNA mismatch repair (MMR) system is composed of enzyme molecules that specifically repair DNA base mismatch. The existence of this system can ensure the integrity and stability of genetic material, avoid the mutation of genetic material, and ensure the high fidelity of DNA replication. It is composed of hMLH1, hMSH2, hpms1, hPMS2 and other genes. HMSH2 is located in human chromosome 2p21-22, encoding a protein composed of 934 aa. The mutation of hMSH2 gene occurs in sporadic colorectal cancer. The mutation of microsatellite hMSH2 gene is related to 50% of familial and non-familial polyposis colorectal cancer (HNPCC).

Formalin-fixed, paraffin-embedded (FFPE) Human Colon cancer tissue with MSH2 Monoclonal Antibody.

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Cat. No	PA6750
Application