Current Position:Home>>Antibodies>>Pathological Antibodies>> MSH6 Monoclonal Antibody
Catalog number:PA6196
Synonyms:MSH6
Reactivity: Human
Applications: IHC-P
Lead Time:Order now, ship in 3 daysWelcome to order from local distributors.
Add to cart Compare Bulk request ManualSize | 3mL/6mL(Ready-to-Use) 100μL/200μL(Concentrated) |
Storage | The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months. |
Source | Mouse |
Reactivity | Human |
Application | IHC-P |
Background | MSH6, known as MutS homolog 6 (E.coli), is a mismatch repair gene. DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite's reproducibility is caused by the slippage of the hinge misalignment during DNA replication, which is also called microsatellite instability. Mutant mismatch repair proteins are often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal cancer (HNPCC), and sporadic (MSI-H) colorectal cancer. MLH1, MSH2, MSH6 antibodies can be used to screen the disease in patients and their families. |